Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle
about
Analysis of mitotic phosphorylation of borealinHistone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis.Molecular analysis of survivin isoforms: evidence that alternatively spliced variants do not play a role in mitosisSpatio-temporal composition of the mitotic Chromosomal Passenger Complex detected using in situ proximity ligation assayCENP-V is required for centromere organization, chromosome alignment and cytokinesis.The Survivin-Crm1 interaction is essential for chromosomal passenger complex localization and functionProteome analysis of the human mitotic spindleThe Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesisThe GAR domain of GAS2L3 mediates binding to the chromosomal passenger complex and is required for localization of GAS2L3 to the constriction zone during abscissionSurvivin mediates targeting of the chromosomal passenger complex to the centromere and midbodyRecruitment of MKLP1 to the spindle midzone/midbody by INCENP is essential for midbody formation and completion of cytokinesis in human cellsUncoupling the central spindle-associated function of the chromosomal passenger complex from its role at centromeresCentromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENPAblation of PRC1 by small interfering RNA demonstrates that cytokinetic abscission requires a central spindle bundle in mammalian cells, whereas completion of furrowing does notEssential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formationThe 3Ms of central spindle assembly: microtubules, motors and MAPsDeath receptor-induced apoptosis reveals a novel interplay between the chromosomal passenger complex and CENP-C during interphaseBub1 is essential for assembly of the functional inner centromere.Centromere RNA is a key component for the assembly of nucleoproteins at the nucleolus and centromereParallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targetsThe Dawn of Aurora Kinase Research: From Fly Genetics to the ClinicThe Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint SignalingDNA damage associated with mitosis and cytokinesis failureAurora B hyperactivation by Bub1 overexpression promotes chromosome missegregationCell division: control of the chromosomal passenger complex in time and spaceReed-Sternberg cells form by abscission failure in the presence of functional Aurora B kinaseThe Aurora Kinase in Trypanosoma brucei plays distinctive roles in metaphase-anaphase transition and cytokinetic initiationThe mitotic regulator Survivin binds as a monomer to its functional interactor BorealinOptimization of Imidazo[4,5- b ]pyridine-Based Kinase Inhibitors: Identification of a Dual FLT3/Aurora Kinase Inhibitor as an Orally Bioavailable Preclinical Development Candidate for the Treatment of Acute Myeloid LeukemiaMolecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres.A novel role for the CBF3 kinetochore-scaffold complex in regulating septin dynamics and cytokinesis.Nbl1p: a Borealin/Dasra/CSC-1-like protein essential for Aurora/Ipl1 complex function and integrity in Saccharomyces cerevisiaeTargeting survivin in cancer therapyDirect association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-CIdentification of a novel chromosomal passenger complex and its unique localization during cytokinesis in Trypanosoma bruceiThe chromosomal passenger complex activates Polo kinase at centromeresSequential assembly of centromeric proteins in male mouse meiosisMERTK Inhibition Induces Polyploidy and Promotes Cell Death and Cellular Senescence in Glioblastoma MultiformeDeducing protein function by forensic integrative cell biologyAurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex
P2860
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P2860
Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Borealin: a novel chromosomal ...... of the bipolar mitotic spindle
@ast
Borealin: a novel chromosomal ...... of the bipolar mitotic spindle
@en
Borealin: a novel chromosomal ...... of the bipolar mitotic spindle
@nl
type
label
Borealin: a novel chromosomal ...... of the bipolar mitotic spindle
@ast
Borealin: a novel chromosomal ...... of the bipolar mitotic spindle
@en
Borealin: a novel chromosomal ...... of the bipolar mitotic spindle
@nl
prefLabel
Borealin: a novel chromosomal ...... of the bipolar mitotic spindle
@ast
Borealin: a novel chromosomal ...... of the bipolar mitotic spindle
@en
Borealin: a novel chromosomal ...... of the bipolar mitotic spindle
@nl
P2093
P2860
P50
P3181
P356
P1476
Borealin: a novel chromosomal ...... of the bipolar mitotic spindle
@en
P2093
Alexander J Henzing
Damien F Hudson
Dietlind L Gerloff
Reiko Honda
Sandrine Ruchaud
P2860
P304
P3181
P356
10.1083/JCB.200404001
P407
P577
2004-07-19T00:00:00Z