Controlling signaling with a specifically designed Gi-coupled receptor
about
Molecular characterization of the melanin-concentrating-hormone receptorEvolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligandEngineered G protein coupled receptors reveal independent regulation of internalization, desensitization and acute signalingDREADDs: novel tools for drug discovery and developmentInvestigating striatal function through cell-type-specific manipulationsMarking embryonic stem cells with a 2A self-cleaving peptide: a NKX2-5 emerald GFP BAC reporterG(i)-coupled GPCR signaling controls the formation and organization of human pluripotent coloniesOptogenetic and Chemogenetic Approaches for Studying Astrocytes and GliotransmittersThe receptors and coding logic for bitter tasteEngineering GPCR signaling pathways with RASSLsCharacterization of human recombinant alpha(2A)-adrenoceptors expressed in Chinese hamster lung cells using intracellular Ca(2+) changes: evidence for cross-talk between recombinant alpha(2A)- and native alpha(1)-adrenoceptorsNeoceptor concept based on molecular complementarity in GPCRs: a mutant adenosine A(3) receptor with selectively enhanced affinity for amine-modified nucleosidesModifying ligand-induced and constitutive signaling of the human 5-HT4 receptorLight-emitting channelrhodopsins for combined optogenetic and chemical-genetic control of neuronsClozapine N-Oxide Administration Produces Behavioral Effects in Long-Evans Rats: Implications for Designing DREADD Experiments.Disrupted bone remodeling leads to cochlear overgrowth and hearing loss in a mouse model of fibrous dysplasia.Morphological and behavioral changes in the pathogenesis of a novel mouse model of communicating hydrocephalus.Conditional expression of a Gi-coupled receptor causes ventricular conduction delay and a lethal cardiomyopathy.Osteoblast expression of an engineered Gs-coupled receptor dramatically increases bone mass.Synergistic Ca2+ responses by G{alpha}i- and G{alpha}q-coupled G-protein-coupled receptors require a single PLC{beta} isoform that is sensitive to both G{beta}{gamma} and G{alpha}q.DREADDs in Drosophila: a pharmacogenetic approach for controlling behavior, neuronal signaling, and physiology in the fly.Ghrelin modulates physiologic and pathologic retinal angiogenesis through GHSR-1aOpioid agonists modify breast cancer cell proliferation by blocking cells to the G2/M phase of the cycle: involvement of cytoskeletal elements.Engineering the melanocortin-4 receptor to control constitutive and ligand-mediated G(S) signaling in vivo.Luciferase activity under direct ligand-dependent control of a muscarinic acetylcholine receptor.Gs-DREADD Knock-In Mice for Tissue-Specific, Temporal Stimulation of Cyclic AMP SignalingSearch for the "ideal analgesic" in pain treatment by engineering the mu-opioid receptor.Tools for resolving functional activity and connectivity within intact neural circuits.Clostridium difficile toxin B differentially affects GPCR-stimulated Ca2+ responses in macrophages: independent roles for Rho and PLA2.Evolution: a guide to perturb protein function and networksCryptotanshinone inhibits cancer cell proliferation by suppressing Mammalian target of rapamycin-mediated cyclin D1 expression and Rb phosphorylation.Adenoviral vectors can impair adrenocortical steroidogenesis: clinical implications for natural infections and gene therapySubstitution of 5-HT1A receptor signaling by a light-activated G protein-coupled receptorNaloxone can act as an analgesic agent without measurable chronic side effects in mice with a mutant mu-opioid receptor expressed in different sites of pain pathway.Xanthatin induces cell cycle arrest at G2/M checkpoint and apoptosis via disrupting NF-κB pathway in A549 non-small-cell lung cancer cells.Beyond the bolus: transgenic tools for investigating the neurophysiology of learning and memory.Enhanced proliferation of cultured human vascular smooth muscle cells linked to increased function of RNA-binding protein HuRTransgenic mice: beyond the knockoutHomology modeling of opioid receptor-ligand complexes using experimental constraintsImaging LDL receptor oligomerization during endocytosis using a co-internalization assay.
P2860
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P2860
Controlling signaling with a specifically designed Gi-coupled receptor
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Controlling signaling with a specifically designed Gi-coupled receptor
@ast
Controlling signaling with a specifically designed Gi-coupled receptor
@en
Controlling signaling with a specifically designed Gi-coupled receptor
@nl
type
label
Controlling signaling with a specifically designed Gi-coupled receptor
@ast
Controlling signaling with a specifically designed Gi-coupled receptor
@en
Controlling signaling with a specifically designed Gi-coupled receptor
@nl
prefLabel
Controlling signaling with a specifically designed Gi-coupled receptor
@ast
Controlling signaling with a specifically designed Gi-coupled receptor
@en
Controlling signaling with a specifically designed Gi-coupled receptor
@nl
P2093
P2860
P3181
P356
P1476
Controlling signaling with a specifically designed Gi-coupled receptor
@en
P2093
B R Conklin
P2860
P3181
P356
10.1073/PNAS.95.1.352
P407
P577
1998-01-06T00:00:00Z