The function of the human homolog of Saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light - Wikidata - awgldk - TriplyDB

The function of the human homolog of Saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light

The function of the human homolog of Saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light

http://www.wikidata.org/entity/Q24681973

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Interactions in the error-prone postreplication repair proteins hREV1, hREV3, and hREV7 Misinsertion and bypass of thymine-thymine dimers by human DNA polymerase iota Separate roles of structured and unstructured regions of Y-family DNA polymerases Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance Ribozyme-mediated REV1 inhibition reduces the frequency of UV-induced mutations in the human HPRT gene The BRCT domain of mammalian Rev1 is involved in regulating DNA translesion synthesis Vertebrate DNA damage tolerance requires the C-terminus but not BRCT or transferase domains of REV1 Structural basis for recruitment of translesion DNA polymerase Pol IV/DinB to the -clamp Structure and Functional Analysis of the BRCT Domain of Translesion Synthesis DNA Polymerase Rev1 NMR Structure and Dynamics of the C-Terminal Domain from Human Rev1 and Its Complex with Rev1 Interacting Region of DNA Polymerase η The mechanisms of UV mutagenesis.Saccharomyces cerevisiae polymerase zeta functions in mitochondria.Balancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?Genomic structure, chromosomal localization and identification of mutations in the xeroderma pigmentosum variant (XPV) gene Structure and enzymatic properties of a stable complex of the human REV1 and REV7 proteins Deoxycytidyl transferase activity of the human REV1 protein is closely associated with the conserved polymerase domain Mammalian translesion DNA synthesis across an acrolein-derived deoxyguanosine adduct. Participation of DNA polymerase eta in error-prone synthesis in human cells Role of single-stranded DNA in targeting REV1 to primer termini Interaction of hREV1 with three human Y-family DNA polymerases Mechanisms of dCMP transferase reactions catalyzed by mouse Rev1 protein Error-free and error-prone lesion bypass by human DNA polymerase kappa in vitro.Response of human REV1 to different DNA damage: preferential dCMP insertion opposite the lesion.The vital role of polymerase ζ and REV1 in mutagenic, but not correct, DNA synthesis across benzo[a]pyrene-dG and recruitment of polymerase ζ by REV1 to replication-stalled site REV1 is implicated in the development of carcinogen-induced lung cancer.Mutagenesis in eukaryotes dependent on DNA polymerase zeta and Rev1p Human DNA polymerase kappa synthesizes DNA with extraordinarily low fidelity.Quantitative measurement of translesion replication in human cells: evidence for bypass of abasic sites by a replicative DNA polymerase.Identification of a protein essential for a major pathway used by human cells to avoid UV- induced DNA damage Transcriptome analysis reveals cyclobutane pyrimidine dimers as a major source of UV-induced DNA breaks.Response of human REV3 gene to gastric cancer inducing carcinogen N-methyl-N'-nitro-N-nitrosoguanidine and its role in mutagenesis.DNA damage control by novel DNA polymerases: translesion replication and mutagenesis.DNA polymerases and somatic hypermutation of immunoglobulin genes Error-prone translesion synthesis mediates acquired chemoresistance Rev1, Rev3, or Rev7 siRNA Abolishes Ultraviolet Light-Induced Translesion Replication in HeLa Cells: A Comprehensive Study Using Alkaline Sucrose Density Gradient Sedimentation.The DNA polymerase activity of Saccharomyces cerevisiae Rev1 is biologically significant.Emerging links between hypermutation of antibody genes and DNA polymerases.The critical mutagenic translesion DNA polymerase Rev1 is highly expressed during G(2)/M phase rather than S phase DNA polymerase zeta (pol zeta) in higher eukaryotes.Sequential assembly of translesion DNA polymerases at UV-induced DNA damage sites A nucleotide binding rectification Brownian ratchet model for translocation of Y-family DNA polymerases

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The function of the human homolog of Saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light

http://www.wikidata.org/entity/Q24681973

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2000 nî lūn-bûn

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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2000 թվականի ապրիլին հրատարակված գիտական հոդված

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2000年の論文

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年學術文章

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The function of the human homo ...... utagenesis induced by UV light

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The function of the human homo ...... utagenesis induced by UV light

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The function of the human homo ...... utagenesis induced by UV light

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The function of the human homo ...... utagenesis induced by UV light

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Proceedings of the National Academy of Sciences of the United States of America

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The function of the human homo ...... utagenesis induced by UV light

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C W Lawrence

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P E Gibbs

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T P McManus

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V M Maher

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W G McGregor

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X D Wang

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Z Li

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P2860

hRAD30 mutations in the variant form of xeroderma pigmentosum

The human REV1 gene codes for a DNA template-dependent dCMP transferase

A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

Deoxycytidyl transferase activity of yeast REV1 protein.

Mutants of yeast defective in mutation induced by ultraviolet light

Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta.

Thymine-thymine dimer bypass by yeast DNA polymerase zeta.

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4186-91

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2026047

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10.1073/PNAS.97.8.4186

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8

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97

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2000-04-11T00:00:00Z

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12556706

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10760286

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Saccharomyces cerevisiae

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18191

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