Dido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stability
about
Dido3 PHD Modulates Cell Differentiation and DivisionRED, a spindle pole-associated protein, is required for kinetochore localization of MAD1, mitotic progression, and activation of the spindle assembly checkpoint.Centromere-localized breaks indicate the generation of DNA damage by the mitotic spindle.Merotelic attachments and non-homologous end joining are the basis of chromosomal instability.PHD and TFIIS-Like domains of the Bye1 transcription factor determine its multivalent genomic distribution.Dido mutations trigger perinatal death and generate brain abnormalities and behavioral alterations in surviving adult mice.Ablation of Dido3 compromises lineage commitment of stem cells in vitro and during early embryonic developmentLinking abnormal mitosis to the acquisition of DNA damageSteroidogenic factor 1 (NR5A1) maintains centrosome homeostasis in steroidogenic cells by restricting centrosomal DNA-dependent protein kinase activationThe death-inducer obliterator 1 (Dido1) gene regulates embryonic stem cell self-renewal.Dido3-dependent HDAC6 targeting controls cilium size.DIDO as a Switchboard that Regulates Self-Renewal and Differentiation in Embryonic Stem Cells.Death inducer-obliterator 1 (Dido1) is a BMP target gene and promotes BMP-induced melanoma progression.CSE1L, DIDO1 and RBM39 in colorectal adenoma to carcinoma progression.
P2860
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P2860
Dido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stability
description
2007 nî lūn-bûn
@nan
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Dido disruption leads to centr ...... promising chromosome stability
@ast
Dido disruption leads to centr ...... promising chromosome stability
@en
Dido disruption leads to centr ...... promising chromosome stability
@nl
type
label
Dido disruption leads to centr ...... promising chromosome stability
@ast
Dido disruption leads to centr ...... promising chromosome stability
@en
Dido disruption leads to centr ...... promising chromosome stability
@nl
prefLabel
Dido disruption leads to centr ...... promising chromosome stability
@ast
Dido disruption leads to centr ...... promising chromosome stability
@en
Dido disruption leads to centr ...... promising chromosome stability
@nl
P2093
P2860
P356
P1476
Dido disruption leads to centr ...... promising chromosome stability
@en
P2093
Agnes Fütterer
Astrid Alonso Guerrero
Carlos Martínez-A
Karel H M van Wely
Varvara Trachana
P2860
P304
P356
10.1073/PNAS.0611132104
P407
P577
2007-02-20T00:00:00Z