Suppression of cell transformation by the cyclin-dependent kinase inhibitor p57KIP2 requires binding to proliferating cell nuclear antigen
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Mutations in the PCNA-binding domain of CDKN1C cause IMAGe syndromeThe cell cycle-regulated B-Myb transcription factor overcomes cyclin-dependent kinase inhibitory activity of p57(KIP2) by interacting with its cyclin-binding domainp15(PAF), a novel PCNA associated factor with increased expression in tumor tissuesInactivation of p57KIP2 by regional promoter hypermethylation and histone deacetylation in human tumorsDirect interaction of proliferating cell nuclear antigen with the small subunit of DNA polymerase deltaGain of function in CDKN1Cp57(Kip2) cooperates with Nurr1 in developing dopamine cellsCommon and specific roles of the related CDK inhibitors p27 and p57 revealed by a knock-in mouse modelCellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15(INK4b)Intrinsic structural disorder and sequence features of the cell cycle inhibitor p57Kip2Global increase in replication fork speed during a p57KIP2-regulated erythroid cell fate switchExpression of p57(KIP2) potently blocks the growth of human astrocytomas and induces cell senescenceThe cyclin-dependent kinase inhibitor p27(Kip1) induces N-terminal proteolytic cleavage of cyclin A.Host genes controlling the susceptibility and resistance to squamous cell carcinoma of the tongue in a rat model.A novel role in DNA metabolism for the binding of Fen1/Rad27 to PCNA and implications for genetic risk.Ubiquitin-mediated proteolysis of vertebrate G1- and S-phase regulators.A novel variant in CDKN1C is associated with intrauterine growth restriction, short stature, and early-adulthood-onset diabetesSilencing of imprinted CDKN1C gene expression is associated with loss of CpG and histone H3 lysine 9 methylation at DMR-LIT1 in esophageal cancer.SLUG-induced elevation of D1 cyclin in breast cancer cells through the inhibition of its ubiquitination.Imprinting disruption of the CDKN1C/KCNQ1OT1 domain: the molecular mechanisms causing Beckwith-Wiedemann syndrome and cancer.Cyclin-dependent kinase 4 phosphorylates and positively regulates PAX3-FOXO1 in human alveolar rhabdomyosarcoma cellsp27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex.Increased protein stability of CDKN1C causes a gain-of-function phenotype in patients with IMAGe syndromeThe cyclin-dependent kinase inhibitor p57Kip2 regulates cell cycle exit, differentiation, and migration of embryonic cerebral cortical precursors.p57(KIP2) is not mutated in hepatoblastoma but shows increased transcriptional activity in a comparative analysis of the three imprinted genes p57(KIP2), IGF2, and H19Characterization, tissue expression, and imprinting analysis of the porcine CDKN1C and NAP1L4 genes.Biochemical and cellular mechanisms of mammalian CDK inhibitors: a few unresolved issues.PAX3-FOXO1 controls expression of the p57Kip2 cell-cycle regulator through degradation of EGR1.Cell survival after UV radiation stress in the unicellular chlorophyte Dunaliella tertiolecta is mediated by DNA repair and MAPK phosphorylationCyclin-dependent kinase inhibitors in yeast, animals, and plants: a functional comparison.A theory for controlling cell cycle dynamics using a reversibly binding inhibitorEpigenetic Characterization of CDKN1C in Placenta Samples from Non-syndromic Intrauterine Growth Restriction.Regulation of cell division by intrinsically unstructured proteins: intrinsic flexibility, modularity, and signaling conduits.Insulin signaling and the regulation of insect diapause.Cyclic changes in gene expression induced by Peg-interferon alfa-2b plus ribavirin in peripheral blood monocytes (PBMC) of hepatitis C patients during the first 10 weeks of treatment.Molecular basis for skeletal variation: insights from developmental genetic studies in mice.Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation.The multiple roles of the cyclin-dependent kinase inhibitory protein p57(KIP2) in cerebral cortical neurogenesis.Epigenetic and genetic alterations of the imprinting disorder Beckwith-Wiedemann syndrome and related disorders.Elevated CO2 alleviates high PAR and UV stress in the unicellular chlorophyte Dunaliella tertiolecta.
P2860
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P2860
Suppression of cell transformation by the cyclin-dependent kinase inhibitor p57KIP2 requires binding to proliferating cell nuclear antigen
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Suppression of cell transforma ...... iferating cell nuclear antigen
@ast
Suppression of cell transforma ...... iferating cell nuclear antigen
@en
Suppression of cell transforma ...... iferating cell nuclear antigen
@nl
type
label
Suppression of cell transforma ...... iferating cell nuclear antigen
@ast
Suppression of cell transforma ...... iferating cell nuclear antigen
@en
Suppression of cell transforma ...... iferating cell nuclear antigen
@nl
prefLabel
Suppression of cell transforma ...... iferating cell nuclear antigen
@ast
Suppression of cell transforma ...... iferating cell nuclear antigen
@en
Suppression of cell transforma ...... iferating cell nuclear antigen
@nl
P2093
P2860
P3181
P356
P1476
Suppression of cell transforma ...... iferating cell nuclear antigen
@en
P2093
H Watanabe
N Schreiber-Agus
R A DePinho
P2860
P304
P3181
P356
10.1073/PNAS.95.4.1392
P407
P577
1998-02-17T00:00:00Z