Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle - Wikidata - awgldk - TriplyDB

Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle

Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle

http://www.wikidata.org/entity/Q24685655

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Molecular mechanisms for survival regulation of chronic myeloid leukemia stem cells Analyzing cold tolerance mechanism in transgenic zebrafish (Danio rerio)Characterization of human SCD2, an oligomeric desaturase with improved stability and enzyme activity by cross-linking in intact cells Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria The role of the small intestine in the development of dietary fat-induced obesity and insulin resistance in C57BL/6J mice.Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver.Reduced levels of SCD1 accentuate palmitate-induced stress in insulin-producing β-cells.Stearoyl-CoA desaturase-2 gene expression is required for lipid synthesis during early skin and liver development Loss of stearoyl-CoA desaturase 1 rescues cardiac function in obese leptin-deficient mice.Role of stearoyl-coenzyme A desaturase in regulating lipid metabolism Stearoyl-CoA desaturase-1 is associated with insulin resistance in morbidly obese subjects.Prospective association of fatty acids in the de novo lipogenesis pathway with risk of type 2 diabetes: the Cardiovascular Health Study.Biochemical and physiological function of stearoyl-CoA desaturase.Stearoyl-coenzyme A desaturase 1 inhibition and the metabolic syndrome: considerations for future drug discovery Atypical antipsychotic medications increase postprandial triglyceride and glucose levels in male rats: relationship with stearoyl-CoA desaturase activity Hepatic oleate regulates adipose tissue lipogenesis and fatty acid oxidation.Omega-3 fatty acid deficiency increases stearoyl-CoA desaturase expression and activity indices in rat liver: positive association with non-fasting plasma triglyceride levels.Vitamin A as a key regulator of obesity & its associated disorders: Evidences from an obese rat model.Metformin inhibits nuclear receptor TR4-mediated hepatic stearoyl-CoA desaturase 1 gene expression with altered insulin sensitivity.Insulin Sensitivity in Adipose and Skeletal Muscle Tissue of Dairy Cows in Response to Dietary Energy Level and 2,4-Thiazolidinedione (TZD).Dietary cystine level affects metabolic rate and glycaemic control in adult mice Scd1 plays a tumor-suppressive role in survival of leukemia stem cells and the development of chronic myeloid leukemia.Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion.Omega-3 fatty acid deficiency augments risperidone-induced hepatic steatosis in rats: positive association with stearoyl-CoA desaturase.Sterculic Oil, a Natural SCD1 Inhibitor, Improves Glucose Tolerance in Obese ob/ob Mice Estimated plasma stearoyl co-A desaturase-1 activity and risk of incident diabetes: the Atherosclerosis Risk in Communities (ARIC) study Thermogenic and metabolic antiobesity drugs: rationale and opportunities.The role of muscle insulin resistance in the pathogenesis of atherogenic dyslipidemia and nonalcoholic fatty liver disease associated with the metabolic syndrome.Stearoyl-CoA desaturase-1 deficiency attenuates obesity and insulin resistance in leptin-resistant obese mice.The role of skeletal muscle sphingolipids in the development of insulin resistance Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet.Skin-specific deletion of stearoyl-CoA desaturase-1 alters skin lipid composition and protects mice from high fat diet-induced obesity.A very low carbohydrate ketogenic diet improves glucose tolerance in ob/ob mice independently of weight loss.Stearoyl-CoA desaturase inhibitors: update on patented compounds.Fenretinide induces ubiquitin-dependent proteasomal degradation of stearoyl-CoA desaturase in human retinal pigment epithelial cells.Diabetes area participation analysis: a review of companies and targets described in the 2008 - 2010 patent literature.Stearoyl CoA desaturase 1: role in cellular inflammation and stress The role of stearoyl-CoA desaturase in obesity, insulin resistance, and inflammation.Role of stearoyl-CoA desaturase-1 in skeletal muscle function and metabolism.

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Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle

http://www.wikidata.org/entity/Q24685655

description

2003 nî lūn-bûn

@nan

2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Stearoyl-CoA desaturase 1 defi ...... osine phosphatase 1B in muscle

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Stearoyl-CoA desaturase 1 defi ...... osine phosphatase 1B in muscle

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Stearoyl-CoA desaturase 1 defi ...... osine phosphatase 1B in muscle

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type

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Stearoyl-CoA desaturase 1 defi ...... osine phosphatase 1B in muscle

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Stearoyl-CoA desaturase 1 defi ...... osine phosphatase 1B in muscle

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Stearoyl-CoA desaturase 1 defi ...... osine phosphatase 1B in muscle

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Stearoyl-CoA desaturase 1 defi ...... osine phosphatase 1B in muscle

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Stearoyl-CoA desaturase 1 defi ...... osine phosphatase 1B in muscle

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Stearoyl-CoA desaturase 1 defi ...... osine phosphatase 1B in muscle

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Proceedings of the National Academy of Sciences of the United States of America

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Stearoyl-CoA desaturase 1 defi ...... osine phosphatase 1B in muscle

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Agnieszka Dobrzyn

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James M Ntambi

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Makoto Miyazaki

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Pawel Dobrzyn

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Seong-Ho Lee

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Shaikh Mizanoor Rahman

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P2860

Insulin stimulates the kinase activity of RAC-PK, a pleckstrin homology domain containing ser/thr kinase

Disruption of IRS-2 causes type 2 diabetes in mice

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Human stearoyl-CoA desaturase: alternative transcripts generated from a single gene by usage of tandem polyadenylation sites

Differentiation-induced gene expression in 3T3-L1 preadipocytes. A second differentially expressed gene encoding stearoyl-CoA desaturase

Potential mechanism of insulin action on glucose transport in the isolated rat adipose cell. Apparent translocation of intracellular transport systems to the plasma membrane

Impaired glucose transport as a cause of decreased insulin-stimulated muscle glycogen synthesis in type 2 diabetes

The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1

Mechanism for differential effect of protein-tyrosine phosphatase 1B on Akt versus mitogen-activated protein kinase in 3T3-L1 adipocytes

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10.1073/PNAS.1934571100

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100

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12960377

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