The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides
about
5'-UTR RNA G-quadruplexes: translation regulation and targetingG4 resolvase 1 binds both DNA and RNA tetramolecular quadruplex with high affinity and is the major source of tetramolecular quadruplex G4-DNA and G4-RNA resolving activity in HeLa cell lysatesIn vivo veritas: using yeast to probe the biological functions of G-quadruplexesThermal difference spectra: a specific signature for nucleic acid structures.Formation of the G-quadruplex and i-motif structures in retinoblastoma susceptibility genes (Rb)Resolution of a structural competition involving dimeric G-quadruplex and its C-rich complementary strand.Zika Virus Genomic RNA Possesses Conserved G-Quadruplexes Characteristic of the Flaviviridae FamilyMethods for Improving Aptamer Binding AffinityMolecular Selection, Modification and Development of Therapeutic Oligonucleotide AptamersThe exception that confirms the rule: a higher-order telomeric G-quadruplex structure more stable in sodium than in potassium.Metal Cations in G-Quadruplex Folding and StabilityExon array analyses across the NCI-60 reveal potential regulation of TOP1 by transcription pausing at guanosine quartets in the first intronGuanines are a quartet's best friend: impact of base substitutions on the kinetics and stability of tetramolecular quadruplexes.Preliminary nanopore cheminformatics analysis of aptamer-target binding strengthA sequence-independent study of the influence of short loop lengths on the stability and topology of intramolecular DNA G-quadruplexes.UV Melting of G-Quadruplexes.QGRS-Conserve: a computational method for discovering evolutionarily conserved G-quadruplex motifs.Fluorescence-based duplex-quadruplex competition test to screen for telomerase RNA quadruplex ligandsAn RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation.How long is too long? Effects of loop size on G-quadruplex stability.Engineering the quadruplex fold: nucleoside conformation determines both folding topology and molecularity in guanine quadruplexes.NMR solution structures of LNA (locked nucleic acid) modified quadruplexes.Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer.Enhanced anti-HIV-1 activity of G-quadruplexes comprising locked nucleic acids and intercalating nucleic acidsProspect of bioflavonoid fisetin as a quadruplex DNA ligand: a biophysical approach.Explaining the varied glycosidic conformational, G-tract length and sequence preferences for anti-parallel G-quadruplexesRudimentary G-quadruplex-based telomere capping in Saccharomyces cerevisiaeA role for WRN in telomere-based DNA damage responses.G-quadruplexes: from guanine gels to chemotherapeuticsBiophysical Characterization of G-Quadruplex Recognition in the PITX1 mRNA by the Specificity Domain of the Helicase RHAU.The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivoA mixed mirror-image DNA/RNA aptamer inhibits glucagon and acutely improves glucose tolerance in models of type 1 and type 2 diabetes.A G-quadruplex stabilizer induces M-phase cell cycle arrestStability of intramolecular quadruplexes: sequence effects in the central loop.G-quadruplexes-novel mediators of gene function.High-resolution three-dimensional NMR structure of the KRAS proto-oncogene promoter reveals key features of a G-quadruplex involved in transcriptional regulation.G-quadruplex induced stabilization by 2'-deoxy-2'-fluoro-D-arabinonucleic acids (2'F-ANA).Stability and bioactivity of thrombin binding aptamers modified with D-/L-isothymidine in the loop regions.5-Hydroxymethyl-2'-deoxyuridine residues in the thrombin binding aptamer: investigating anticoagulant activity by making a tiny chemical modification.Unfolding and conformational variations of thrombin-binding DNA aptamers: synthesis, circular dichroism and molecular dynamics simulations.
P2860
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P2860
The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides
description
2005 nî lūn-bûn
@nan
2005 թուականին հրատարակուած գիտական յօդուած
@hyw
2005 թվականին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The effect of chemical modific ...... uplex-forming oligonucleotides
@ast
The effect of chemical modific ...... uplex-forming oligonucleotides
@en
The effect of chemical modific ...... uplex-forming oligonucleotides
@nl
type
label
The effect of chemical modific ...... uplex-forming oligonucleotides
@ast
The effect of chemical modific ...... uplex-forming oligonucleotides
@en
The effect of chemical modific ...... uplex-forming oligonucleotides
@nl
prefLabel
The effect of chemical modific ...... uplex-forming oligonucleotides
@ast
The effect of chemical modific ...... uplex-forming oligonucleotides
@en
The effect of chemical modific ...... uplex-forming oligonucleotides
@nl
P2860
P50
P3181
P356
P1476
The effect of chemical modific ...... uplex-forming oligonucleotides
@en
P2093
Barbara Saccà
P2860
P304
P3181
P356
10.1093/NAR/GKI257
P407
P577
2005-02-24T00:00:00Z