Lipoxygenase and cyclooxygenase metabolism: new insights in treatment and chemoprevention of pancreatic cancer - Wikidata - awgldk - TriplyDB

Lipoxygenase and cyclooxygenase metabolism: new insights in treatment and chemoprevention of pancreatic cancer

Lipoxygenase and cyclooxygenase metabolism: new insights in treatment and chemoprevention of pancreatic cancer

http://www.wikidata.org/entity/Q24800010

about

Molecular Targeted Intervention for Pancreatic Cancer BLT2 is expressed in PanINs, IPMNs, pancreatic cancer and stimulates tumour cell proliferation Exploring the functions of RNA interference pathway proteins: some functions are more RISCy than others?Meta-analysis of microarray data on pancreatic cancer defines a set of commonly dysregulated genes.A triple combination of atorvastatin, celecoxib and tipifarnib strongly inhibits pancreatic cancer cells and xenograft pancreatic tumors Phenotype and genotype of pancreatic cancer cell lines Biological approaches to therapy of pancreatic cancer.Pancreatic cancer: molecular pathogenesis and new therapeutic targets.Chemoprevention strategies for pancreatic cancer Effect of 15-lipoxygenase metabolites on angiogenesis: 15(S)-HPETE is angiostatic and 15(S)-HETE is angiogenic.Metabolomic evaluation of Mitomycin C and rapamycin in a personalized treatment of pancreatic cancer.Celecoxib and GABA cooperatively prevent the progression of pancreatic cancer in vitro and in xenograft models of stress-free and stress-exposed mice The Kaposi's sarcoma-associated herpesvirus (KSHV)-induced 5-lipoxygenase-leukotriene B4 cascade plays key roles in KSHV latency, monocyte recruitment, and lipogenesis.Urinary prostaglandin E2 metabolite and pancreatic cancer risk: case-control study in urban Shanghai Mucin 1 Regulates Cox-2 Gene in Pancreatic Cancer.Synthesis and Biological Evaluation of New Phthalazinone Derivatives as Anti-Inflammatory and Anti-Proliferative Agents.15-lipoxygenase-1 production is lost in pancreatic cancer and overexpression of the gene inhibits tumor cell growth.What are cyclooxygenases and lipoxygenases doing in the driver's seat of carcinogenesis?Acyl-CoA synthetase-4, a new regulator of mTOR and a potential therapeutic target for enhanced estrogen receptor function in receptor-positive and -negative breast cancer Risk factors and therapeutic targets in pancreatic cancer.Novel dual cyclooxygenase and lipoxygenase inhibitors targeting hyaluronan-CD44v6 pathway and inducing cytotoxicity in colon cancer cells.Molecular changes in pancreatic cancer.Role of abnormal lipid metabolism in development, progression, diagnosis and therapy of pancreatic cancer.Neurotransmitter receptors as central regulators of pancreatic cancer Eicosanoids in inflammation and cancer: the role of COX-2.Dietary phytochemicals alter epigenetic events and signaling pathways for inhibition of metastasis cascade: phytoblockers of metastasis cascade.Regulation of vascular endothelial growth factor by metabolic context of the cell.Synthesis and Biological Evaluation of N-(5-(pyridin-2-yl)-1,3,4-thiadiazol-2-yl)benzamide Derivatives as Lipoxygenase Inhibitor with Potential Anticancer Activity.Hepatitis B virus X protein promotes liver cell proliferation via a positive cascade loop involving arachidonic acid metabolism and p-ERK1/2.Curcumin augments gemcitabine cytotoxic effect on pancreatic adenocarcinoma cell lines.Anti-apoptotic effects of arachidonic acid and prostaglandin E2 in pancreatic beta-cells.Extracellular matrix stimulates reactive oxygen species production and increases pancreatic cancer cell survival through 5-lipoxygenase and NADPH oxidase.The effect of n-3/n-6 polyunsaturated fatty acids on acute reflux esophagitis in rats.Convergent oxygenation of arachidonic acid by 5-lipoxygenase and cyclooxygenase-2.Arachidonic Acid Metabolite as a Novel Therapeutic Target in Breast Cancer Metastasis.Ras-induced invasion and metastasis are regulated by a leukotriene B4 receptor BLT2-linked pathway.

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Lipoxygenase and cyclooxygenase metabolism: new insights in treatment and chemoprevention of pancreatic cancer

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2003年の論文

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Lipoxygenase and cyclooxygenas ...... revention of pancreatic cancer

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Lipoxygenase and cyclooxygenas ...... revention of pancreatic cancer

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Lipoxygenase and cyclooxygenas ...... revention of pancreatic cancer

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Lipoxygenase and cyclooxygenas ...... revention of pancreatic cancer

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Molecular Cancer

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Lipoxygenase and cyclooxygenas ...... revention of pancreatic cancer

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Rene Hennig

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Thomas E Adrian

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Xian-Zhong Ding

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P2860

Platelet-type 12-lipoxygenase in a human prostate carcinoma stimulates angiogenesis and tumor growth

COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression

Chronic immune activation and inflammation as the cause of malignancy

5-Lipoxygenase and leukotriene B(4) receptor are expressed in human pancreatic cancers but not in pancreatic ducts in normal tissue

Increased expression of cyclooxygenase-2 in human pancreatic neoplasms and potential for chemoprevention by cyclooxygenase inhibitors

Aspirin inhibits matrix metalloproteinase-2 activity, increases E-cadherin production, and inhibits in vitro invasion of tumor cells

Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacologic, and clinical issues

Association between nonsteroidal anti-inflammatory drug use and the incidence of pancreatic cancer

Prostaglandins and leukotrienes: advances in eicosanoid biology

Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues

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