Microarray analysis reveals genetic pathways modulated by tipifarnib in acute myeloid leukemia - Wikidata - awgldk - TriplyDB

Microarray analysis reveals genetic pathways modulated by tipifarnib in acute myeloid leukemia

Microarray analysis reveals genetic pathways modulated by tipifarnib in acute myeloid leukemia

http://www.wikidata.org/entity/Q24805262

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The clinically relevant pharmacogenomic changes in acute myelogenous leukemia Multiple Transcriptome Data Analysis Reveals Biologically Relevant Atopic Dermatitis Signature Genes and Pathways Mechanistic exploration of phthalimide neovascular factor 1 using network analysis tools.Suicide candidate genes associated with bipolar disorder and schizophrenia: an exploratory gene expression profiling analysis of post-mortem prefrontal cortex Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via logistic mixed models.Genomic and geographic distribution of private SNPs and pathways in human populations Driven to death: Inhibition of farnesylation increases Ras activity and promotes growth arrest and cell death [corrected]Successful in vitro expansion and differentiation of cord blood derived CD34+ cells into early endothelial progenitor cells reveals highly differential gene expression iTRAQ: a method to elucidate cellular responses to mycotoxin zearalenone.Targeting of CD34+CD38- cells using Gemtuzumab ozogamicin (Mylotarg) in combination with tipifarnib (Zarnestra) in Acute Myeloid Leukaemia.Combined proteomics and pathways analysis of collecting duct reveals a protein regulatory network activated in vasopressin escape.Validation of MIMGO: a method to identify differentially expressed GO terms in a microarray dataset Network of brain protein level changes in glutaminase deficient fetal mice Lipid posttranslational modifications. Farnesyl transferase inhibitors.Metagenomic analysis on seasonal microbial variations of activated sludge from a full-scale wastewater treatment plant over 4 years.Opposing effects of monomeric and pentameric C-reactive protein on endothelial progenitor cells.Multi-institutional phase 2 clinical and pharmacogenomic trial of tipifarnib plus etoposide for elderly adults with newly diagnosed acute myelogenous leukemia Inter-chromosomal variation in the pattern of human population genetic structure.A phase II trial of capecitabine in combination with the farnesyltransferase inhibitor tipifarnib in patients with anthracycline-treated and taxane-resistant metastatic breast cancer: an Eastern Cooperative Oncology Group Study (E1103).Computational characterization of proteins.Tipifarnib-mediated suppression of T-bet-dependent signaling pathways.Development of the farnesyltransferase inhibitor tipifarnib for therapy of hematologic malignancies.Development of farnesyltransferase inhibitors for clinical cancer therapy: focus on hematologic malignancies.Farnesyltransferase inhibitors and their potential role in therapy for myelodysplastic syndromes and acute myeloid leukaemia.Combined p21-activated kinase and farnesyltransferase inhibitor treatment exhibits enhanced anti-proliferative activity on melanoma, colon and lung cancer cell lines.Motif-specific sampling of phosphoproteomes.Farnesyltransferase inhibitor R115777 inhibits cell growth and induces apoptosis in mantle cell lymphoma.Applications of microarray technology to Acute Myelogenous Leukemia Tipifarnib in the treatment of newly diagnosed acute myelogenous leukemia.Recent advances in platelet proteomics.Tipifarnib in the treatment of acute myeloid leukemia.Pharmacologic profiling of transcriptional targets deciphers promoter logic.Distinct set of kinases induced after retrieval of spatial memory discriminate memory modulation processes in the mouse hippocampus.Strain-independent global effect of hippocampal proteins in mice trained in the Morris water maze.

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Microarray analysis reveals genetic pathways modulated by tipifarnib in acute myeloid leukemia

http://www.wikidata.org/entity/Q24805262

description

2004 nî lūn-bûn

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2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2004 թվականի օգոստոսին հրատարակված գիտական հոդված

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Microarray analysis reveals ge ...... rnib in acute myeloid leukemia

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Microarray analysis reveals ge ...... rnib in acute myeloid leukemia

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Microarray analysis reveals ge ...... rnib in acute myeloid leukemia

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Microarray analysis reveals ge ...... rnib in acute myeloid leukemia

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Microarray analysis reveals ge ...... rnib in acute myeloid leukemia

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Microarray analysis reveals ge ...... rnib in acute myeloid leukemia

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David Atkins

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Jeffrey E Lancet

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Judith E Karp

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Mitch Raponi

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Robert T Belly

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Yixin Wang

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P2860

Farnesyltransferase inhibitor tipifarnib is well tolerated, induces stabilization of disease, and inhibits farnesylation and oncogenic/tumor survival pathways in patients with advanced multiple myeloma

Cell-cycle-dependent activation of mitogen-activated protein kinase kinase (MEK-1/2) in myeloid leukemia cell lines and induction of growth inhibition and apoptosis by inhibitors of RAS signaling

Characterization of the antitumor effects of the selective farnesyl protein transferase inhibitor R115777 in vivo and in vitro.

The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis

K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors.

Farnesyltransferase inhibitors: promises and realities.

Farnesyl transferase inhibitors as anticancer agents.

Clinical development of farnesyltransferase inhibitors in leukemias and myelodysplastic syndrome.

Farnesyltransferase inhibitors in hematologic malignancies: new horizons in therapy.

Global modulation of cellular transcription by human cytomegalovirus is initiated by viral glycoprotein B.

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10.1186/1471-2407-4-56

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1036401277

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516036

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