Hedgehog signal transduction proteins: contacts of the Fused kinase and Ci transcription factor with the kinesin-related protein Costal2.
about
The FU gene and its possible protein isoformsMice deficient in the fused homolog do not exhibit phenotypes indicative of perturbed hedgehog signaling during embryonic developmentSuppressor of fused regulates Gli activity through a dual binding mechanismCYK4 promotes antiparallel microtubule bundling by optimizing MKLP1 neck conformationCostal2 functions as a kinesin-like protein in the hedgehog signal transduction pathwayHedgehog signaling downregulates suppressor of fused through the HIB/SPOP-Crn axis in Drosophila.Gli2a protein localization reveals a role for Iguana/DZIP1 in primary ciliogenesis and a dependence of Hedgehog signal transduction on primary cilia in the zebrafish.KIF7 mutations cause fetal hydrolethalus and acrocallosal syndromes.Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail.Regulation of Hedgehog signaling: a complex story.The role of kinases in the Hedgehog signalling pathway.Hedgehog activates fused through phosphorylation to elicit a full spectrum of pathway responsesContributions of Costal 2-Fused interactions to Hedgehog signaling in DrosophilaA Comparison of Ci/Gli Activity as Regulated by Sufu in Drosophila and Mammalian Hedgehog ResponseA Genetic Screen for Mutations Affecting Cell Division in the Arabidopsis thaliana Embryo Identifies Seven Loci Required for Cytokinesis.Fused-Costal2 protein complex regulates Hedgehog-induced Smo phosphorylation and cell-surface accumulationExtramacrochaetae imposes order on the Drosophila eye by refining the activity of the Hedgehog signaling gradientThe Kinesin-related protein Costal2 associates with membranes in a Hedgehog-sensitive, Smoothened-independent manner.An intramolecular association between two domains of the protein kinase Fused is necessary for Hedgehog signaling.Non-cell-autonomous signaling by Shh in tumors: challenges and opportunities for therapeutic targets.The Hedgehog signal transduction network.Transcriptional regulation of graded Hedgehog signalingMicrotubule Motors Drive Hedgehog Signaling in Primary Cilia.Costal 2 interactions with Cubitus interruptus (Ci) underlying Hedgehog-regulated Ci processingBiophysical characterisation of the novel zinc binding property in Suppressor of Fused.Regulation of mammalian Gli proteins by Costal 2 and PKA in Drosophila reveals Hedgehog pathway conservation.Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog.Over-expression of a novel nuclear interactor of Suppressor of fused, the Drosophila myelodysplasia/myeloid leukaemia factor, induces abnormal morphogenesis associated with increased apoptosis and DNA synthesis.
P2860
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P2860
Hedgehog signal transduction proteins: contacts of the Fused kinase and Ci transcription factor with the kinesin-related protein Costal2.
description
2002 nî lūn-bûn
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2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
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2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Hedgehog signal transduction p ...... inesin-related protein Costal2
@nl
Hedgehog signal transduction p ...... nesin-related protein Costal2.
@ast
Hedgehog signal transduction p ...... nesin-related protein Costal2.
@en
type
label
Hedgehog signal transduction p ...... inesin-related protein Costal2
@nl
Hedgehog signal transduction p ...... nesin-related protein Costal2.
@ast
Hedgehog signal transduction p ...... nesin-related protein Costal2.
@en
prefLabel
Hedgehog signal transduction p ...... inesin-related protein Costal2
@nl
Hedgehog signal transduction p ...... nesin-related protein Costal2.
@ast
Hedgehog signal transduction p ...... nesin-related protein Costal2.
@en
P2093
P2860
P356
P1476
Hedgehog signal transduction p ...... nesin-related protein Costal2.
@en
P2093
Anne Plessis
Karen S Ho
Matthew P Scott
Matthieu Sanial
Véronique Monnier
P2860
P2888
P356
10.1186/1471-213X-2-4
P407
P577
2002-03-19T00:00:00Z
P6179
1034322166