Mechanistic features of CAG*CTG repeat contractions in cultured cells revealed by a novel genetic assay
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Zinc-finger directed double-strand breaks within CAG repeat tracts promote repeat instability in human cellsInstability of CTG repeats is governed by the position of a DNA base lesion through base excision repairNucleotide excision repair, mismatch repair, and R-loops modulate convergent transcription-induced cell death and repeat instabilityNon-B DNA structure-induced genetic instability and evolution.CAG*CTG repeat instability in cultured human astrocytesReplication in mammalian cells recapitulates the locus-specific differences in somatic instability of genomic GAA triplet-repeatsContracting CAG/CTG repeats using the CRISPR-Cas9 nickase.DNA mismatch repair complex MutSβ promotes GAA·TTC repeat expansion in human cellsHuman mismatch repair protein hMutLα is required to repair short slipped-DNAs of trinucleotide repeats.Advances in Huntington's disease diagnostics: development of a standard reference material.Trinucleotide repeat expansions catalyzed by human cell-free extractsCoordinated processing of 3' slipped (CAG)n/(CTG)n hairpins by DNA polymerases β and δ preferentially induces repeat expansions.Methods to determine DNA structural alterations and genetic instability.Proofreading and secondary structure processing determine the orientation dependence of CAG x CTG trinucleotide repeat instability in Escherichia coli.MutSβ abundance and Msh3 ATP hydrolysis activity are important drivers of CTG•CAG repeat expansions.Non-LTR retrotransposons and microsatellites: Partners in genomic variation
P2860
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P2860
Mechanistic features of CAG*CTG repeat contractions in cultured cells revealed by a novel genetic assay
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2005 nî lūn-bûn
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2005 թուականին հրատարակուած գիտական յօդուած
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2005 թվականին հրատարակված գիտական հոդված
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2005年の論文
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2005年論文
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2005年論文
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2005年論文
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2005年論文
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2005年論文
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2005年论文
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name
Mechanistic features of CAG*CT ...... ealed by a novel genetic assay
@ast
Mechanistic features of CAG*CT ...... ealed by a novel genetic assay
@en
Mechanistic features of CAG*CT ...... ealed by a novel genetic assay
@nl
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label
Mechanistic features of CAG*CT ...... ealed by a novel genetic assay
@ast
Mechanistic features of CAG*CT ...... ealed by a novel genetic assay
@en
Mechanistic features of CAG*CT ...... ealed by a novel genetic assay
@nl
prefLabel
Mechanistic features of CAG*CT ...... ealed by a novel genetic assay
@ast
Mechanistic features of CAG*CT ...... ealed by a novel genetic assay
@en
Mechanistic features of CAG*CT ...... ealed by a novel genetic assay
@nl
P2093
P2860
P3181
P356
P1476
Mechanistic features of CAG*CT ...... ealed by a novel genetic assay
@en
P2093
Brian T Farrell
Juan José Miret
Richard Pelletier
Robert S Lahue
P2860
P304
P3181
P356
10.1093/NAR/GKI880
P407
P577
2005-01-01T00:00:00Z