A T-stem slip in human mitochondrial tRNALeu(CUN) governs its charging capacity
about
A new mechanism for mtDNA pathogenesis: impairment of post-transcriptional maturation leads to severe depletion of mitochondrial tRNASer(UCN) caused by T7512C and G7497A point mutations.Accurate energies of hydrogen bonded nucleic acid base pairs and triplets in tRNA tertiary interactions.Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetaseA deafness-associated tRNAHis mutation alters the mitochondrial function, ROS production and membrane potential.In vivo identification of essential nucleotides in tRNALeu to its functions by using a constructed yeast tRNALeu knockout strain.Degenerate connective polypeptide 1 (CP1) domain from human mitochondrial leucyl-tRNA synthetase.The Mitonuclear Dimension of Neanderthal and Denisovan Ancestry in Modern Human Genomes.Multilevel functional and structural defects induced by two pathogenic mitochondrial tRNA mutations.A naturally occurring nonapeptide functionally compensates for the CP1 domain of leucyl-tRNA synthetase to modulate aminoacylation activity.A hypertension-associated mitochondrial DNA mutation alters the tertiary interaction and function of tRNALeu(UUR).A natural non-Watson-Crick base pair in human mitochondrial tRNAThr causes structural and functional susceptibility to local mutations.
P2860
Q24810699-967AF7BC-39D0-4A4B-A1A4-18D2157C6C53Q25257425-67226359-899E-4003-A4AC-80AC10ED1199Q27679720-79AF5306-DE16-4D4B-B15C-F03B25E460EBQ33843127-F5ACFC0A-3C83-4F62-A749-CEF57175363CQ34392129-E610C8C1-ACBF-44B9-B1F0-84267A80CAE6Q36115847-EB48A080-2F6F-4265-8D21-290EDDE27E03Q38601986-FD8A97A5-53A9-443E-A587-69DFB0474E44Q39427538-9054287D-69FD-4A1C-AFF0-47A3BB0E652AQ39658077-A7980772-24DB-42A0-AE70-ADC73EA11EAAQ40146692-513DFC76-3CFE-48FE-8085-14F1CB5BBD9FQ52691120-A9DFECBC-8499-44FB-81E3-DD56A0A3C9AD
P2860
A T-stem slip in human mitochondrial tRNALeu(CUN) governs its charging capacity
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
A T-stem slip in human mitochondrial tRNALeu(CUN) governs its charging capacity
@ast
A T-stem slip in human mitochondrial tRNALeu(CUN) governs its charging capacity
@en
A T-stem slip in human mitochondrial tRNALeu(CUN) governs its charging capacity
@nl
type
label
A T-stem slip in human mitochondrial tRNALeu(CUN) governs its charging capacity
@ast
A T-stem slip in human mitochondrial tRNALeu(CUN) governs its charging capacity
@en
A T-stem slip in human mitochondrial tRNALeu(CUN) governs its charging capacity
@nl
prefLabel
A T-stem slip in human mitochondrial tRNALeu(CUN) governs its charging capacity
@ast
A T-stem slip in human mitochondrial tRNALeu(CUN) governs its charging capacity
@en
A T-stem slip in human mitochondrial tRNALeu(CUN) governs its charging capacity
@nl
P2093
P2860
P356
P1476
A T-stem slip in human mitochondrial tRNALeu(CUN) governs its charging capacity
@en
P2093
En-Duo Wang
Ming-Wei Zhao
Yong-Neng Yao
Zhan-Xi Hao
P2860
P304
P356
10.1093/NAR/GKI677
P407
P577
2005-06-22T00:00:00Z