DNA damage and replication stress induced transcription of RNR genes is dependent on the Ccr4-Not complex. - Wikidata - awgldk - TriplyDB

DNA damage and replication stress induced transcription of RNR genes is dependent on the Ccr4-Not complex.

DNA damage and replication stress induced transcription of RNR genes is dependent on the Ccr4-Not complex.

http://www.wikidata.org/entity/Q24815044

about

Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth Involvement of the SMRT/NCoR-HDAC3 complex in transcriptional repression by the CNOT2 subunit of the human Ccr4-Not complex Human Ccr4-Not complexes contain variable deadenylase subunits Ccr4-Not complex: the control freak of eukaryotic cells The Not4 RING E3 Ligase: A Relevant Player in Cotranslational Quality Control A SAGA-independent function of SPT3 mediates transcriptional deregulation in a mutant of the Ccr4-not complex in Saccharomyces cerevisiae.A genetic screen for increased loss of heterozygosity in Saccharomyces cerevisiae.The multifunctional Ccr4-Not complex directly promotes transcription elongation Suppression of intragenic transcription requires the MOT1 and NC2 regulators of TATA-binding protein Phosphorylation of Not4p functions parallel to BUR2 to regulate resistance to cellular stresses in Saccharomyces cerevisiae Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction.Genome-wide analysis of factors affecting transcription elongation and DNA repair: a new role for PAF and Ccr4-not in transcription-coupled repair.Comparative genome-wide screening identifies a conserved doxorubicin repair network that is diploid specific in Saccharomyces cerevisiae Functional dissection of a HECT ubiquitin E3 ligase.Multifunctional roles of the mammalian CCR4-NOT complex in physiological phenomena.Ubc4 and Not4 regulate steady-state levels of DNA polymerase-α to promote efficient and accurate DNA replication.Defining genetic factors that modulate intergenerational CAG repeat instability in Drosophila melanogaster Alpha-synuclein functions in the nucleus to protect against hydroxyurea-induced replication stress in yeast.Analyzing the dose-dependence of the Saccharomyces cerevisiae global transcriptional response to methyl methanesulfonate and ionizing radiation.Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotype Quantitative proteomics of the yeast Hsp70/Hsp90 interactomes during DNA damage reveal chaperone-dependent regulation of ribonucleotide reductase.Modulation of Ubc4p/Ubc5p-mediated stress responses by the RING-finger-dependent ubiquitin-protein ligase Not4p in Saccharomyces cerevisiae Oxidative-stress-induced nuclear to cytoplasmic relocalization is required for Not4-dependent cyclin C destruction Increased tRNA modification and gene-specific codon usage regulate cell cycle progression during the DNA damage response Novel connections between DNA replication, telomere homeostasis, and the DNA damage response revealed by a genome-wide screen for TEL1/ATM interactions in Saccharomyces cerevisiae.Yeast Rap1 contributes to genomic integrity by activating DNA damage repair genes The cellular roles of Ccr4-NOT in model and pathogenic fungi-implications for fungal virulence Deadenylation: enzymes, regulation, and functional implications.Divergence of the expression and subcellular localization of CCR4-associated factor 1 (CAF1) deadenylase proteins in Oryza sativa.Caf1 regulates translocation of ribonucleotide reductase by releasing nucleoplasmic Spd1-Suc22 assembly.Regulation of histone H3K4 tri-methylation and PAF complex recruitment by the Ccr4-Not complex.Ribonucleotide reductase regulation in response to genotoxic stress in Arabidopsis.The Ccr4-Not Complex: Architecture and Structural Insights.Def1 interacts with TFIIH and modulates RNA polymerase II transcription.Genotoxicity of chemical compounds identification and assessment by yeast cells transformed with GFP reporter constructs regulated by the PLM2 or DIN7 promoter.Beyond the known functions of the CCR4-NOT complex in gene expression regulatory mechanisms: New structural insights to unravel CCR4-NOT mRNA processing machinery.Reparameterization of PAM50 expression identifies novel breast tumor dimensions and leads to discovery of a genomewide significant breast cancer locus at 12q15.Degradation of a novel DNA damage response protein, tankyrase 1 binding protein 1 (Tab182), following adenovirus infection.Transcriptome analysis reveals new microRNAs-mediated pathway involved in anther development in male sterile wheat.Upregulation of dNTP Levels After Telomerase Inactivation Influences Telomerase-Independent Telomere Maintenance Pathway Choice in

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DNA damage and replication stress induced transcription of RNR genes is dependent on the Ccr4-Not complex.

http://www.wikidata.org/entity/Q24815044

description

2005 nî lūn-bûn

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2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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name

DNA damage and replication str ...... endent on the Ccr4-Not complex

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DNA damage and replication str ...... ndent on the Ccr4-Not complex.

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DNA damage and replication str ...... ndent on the Ccr4-Not complex.

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DNA damage and replication str ...... endent on the Ccr4-Not complex

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DNA damage and replication str ...... ndent on the Ccr4-Not complex.

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DNA damage and replication str ...... ndent on the Ccr4-Not complex.

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DNA damage and replication str ...... endent on the Ccr4-Not complex

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DNA damage and replication str ...... ndent on the Ccr4-Not complex.

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DNA damage and replication str ...... ndent on the Ccr4-Not complex.

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Nucleic Acids Research

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DNA damage and replication str ...... endent on the Ccr4-Not complex

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H Th Marc Timmers

http://www.w3.org/2001/XMLSchema#string

Klaas W Mulder

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P2860

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits.

CCR4, a 3'-5' poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase.

Repression of promoter activity by CNOT2, a subunit of the transcription regulatory Ccr4-not complex

An altered-specificity ubiquitin-conjugating enzyme/ubiquitin-protein ligase pair

The structure of the C4C4 ring finger of human NOT4 reveals features distinct from those of C3HC4 RING fingers

Rnr4p, a novel ribonucleotide reductase small-subunit protein

The Ccr4-Not complex independently controls both Msn2-dependent transcriptional activation--via a newly identified Glc7/Bud14 type I protein phosphatase module--and TFIID promoter distribution.

Genetic evidence supports a role for the yeast CCR4-NOT complex in transcriptional elongation.

Cell cycle progression in G1 and S phases is CCR4 dependent following ionizing radiation or replication stress in Saccharomyces cerevisiae.

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10.1093/NAR/GKI938

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