2'-deoxy-2'-fluoro-beta-D-arabinonucleic acid (2'F-ANA) modified oligonucleotides (ON) effect highly efficient, and persistent, gene silencing
about
Improvements in siRNA properties mediated by 2'-deoxy-2'-fluoro-beta-D-arabinonucleic acid (FANA)The solution structure of double helical arabino nucleic acids (ANA and 2'F-ANA): effect of arabinoses in duplex-hairpin interconversionEltrombopag modulates reactive oxygen species and decreases acute myeloid leukemia cell survivalImpact of sugar pucker on base pair and mispair stability.Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencingStructure/affinity studies in the bicyclo-DNA series: Synthesis and properties of oligonucleotides containing bc(en)-T and iso-tricyclo-T nucleosides.Regulating gene expression in human leukemia cells using light-activated oligodeoxynucleotides.Effects of local mRNA structure on posttranscriptional gene silencing.The versatility of oligonucleotides as potential therapeutics.Carrier-free Gene Silencing by Amphiphilic Nucleic Acid Conjugates in Differentiated Intestinal Cells.Enzymatic recognition of 2'-modified ribonucleoside 5'-triphosphates: towards the evolution of versatile aptamers.Nucleic acid drugs in the clinic.G-quadruplex induced stabilization by 2'-deoxy-2'-fluoro-D-arabinonucleic acids (2'F-ANA).Structure variations of TBA G-quadruplex induced by 2'-O-methyl nucleotide in K+ and Ca2+ environments.Sugar-modified G-quadruplexes: effects of LNA-, 2'F-RNA- and 2'F-ANA-guanosine chemistries on G-quadruplex structure and stability.5'-O-Methylphosphonate nucleic acids--new modified DNAs that increase the Escherichia coli RNase H cleavage rate of hybrid duplexes.Antisense 2'-Deoxy, 2'-Fluroarabino Nucleic Acids (2'F-ANAs) Oligonucleotides: In Vitro Gymnotic Silencers of Gene Expression Whose Potency Is Enhanced by Fatty Acids.Gapmer Antisense Oligonucleotides Suppress the Mutant Allele of COL6A3 and Restore Functional Protein in Ullrich Muscular Dystrophy.Evidence for a dual functional role of a conserved histidine in RNA·DNA heteroduplex cleavage by human RNase H1.Recombinant purine nucleoside phosphorylases from thermophiles: preparation, properties and activity towards purine and pyrimidine nucleosides.Stereoselective synthesis of 2-deoxy-2-fluoroarabinofuranosyl-alpha-1-phosphate and its application to the synthesis of 2'-deoxy-2'-fluoroarabinofuranosyl purine nucleosides by a chemo-enzymatic method.2'β-Fluoro-Tricyclo Nucleic Acids (2'F-tc-ANA): Thermal Duplex Stability, Structural Studies, and RNase H Activation.Activation of Frataxin Protein Expression by Antisense Oligonucleotides Targeting the Mutant Expanded Repeat.Synthesis and biological applications of fluoro-modified nucleic acids.
P2860
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P2860
2'-deoxy-2'-fluoro-beta-D-arabinonucleic acid (2'F-ANA) modified oligonucleotides (ON) effect highly efficient, and persistent, gene silencing
description
2006 nî lūn-bûn
@nan
2006 թուականին հրատարակուած գիտական յօդուած
@hyw
2006 թվականին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
2'-deoxy-2'-fluoro-beta-D-arab ...... and persistent, gene silencing
@ast
2'-deoxy-2'-fluoro-beta-D-arab ...... and persistent, gene silencing
@en
2'-deoxy-2'-fluoro-beta-D-arab ...... and persistent, gene silencing
@nl
type
label
2'-deoxy-2'-fluoro-beta-D-arab ...... and persistent, gene silencing
@ast
2'-deoxy-2'-fluoro-beta-D-arab ...... and persistent, gene silencing
@en
2'-deoxy-2'-fluoro-beta-D-arab ...... and persistent, gene silencing
@nl
prefLabel
2'-deoxy-2'-fluoro-beta-D-arab ...... and persistent, gene silencing
@ast
2'-deoxy-2'-fluoro-beta-D-arab ...... and persistent, gene silencing
@en
2'-deoxy-2'-fluoro-beta-D-arab ...... and persistent, gene silencing
@nl
P2093
P2860
P3181
P356
P1476
2'-deoxy-2'-fluoro-beta-D-arab ...... and persistent, gene silencing
@en
P2093
A M Gewirtz
C R Swider
E Viazovkina
M Elzagheid
P2860
P304
P3181
P356
10.1093/NAR/GKJ455
P407
P577
2006-01-01T00:00:00Z