Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function
about
Pathogenic mechanism of an autism-associated neuroligin mutation involves altered AMPA-receptor traffickingAutism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors.Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutationThe neurexin ligands, neuroligins and leucine-rich repeat transmembrane proteins, perform convergent and divergent synaptic functions in vivoClinical and Neurobiological Relevance of Current Animal Models of Autism Spectrum Disorders.Astrocytes and Microglia and Their Potential Link with Autism Spectrum DisordersStriatal Circuits as a Common Node for Autism PathophysiologyAutism Spectrum Disorders and Drug Addiction: Common Pathways, Common Molecules, Distinct Disorders?On the Role of Glutamate in Presynaptic Development: Possible Contributions of Presynaptic NMDA ReceptorsBehavioral phenotypes of genetic mouse models of autism.Assessing and Stabilizing Aberrant Neuroplasticity in Autism Spectrum Disorder: The Potential Role of Transcranial Magnetic StimulationFollowing the genes: a framework for animal modeling of psychiatric disordersDeep molecular diversity of mammalian synapses: why it matters and how to measure itGABAergic signaling as therapeutic target for autism spectrum disordersNeuroligins provide molecular links between syndromic and nonsyndromic autismBehavioral and Neuroanatomical Phenotypes in Mouse Models of AutismHippocampal neuroligin-2 overexpression leads to reduced aggression and inhibited novelty reactivity in ratsPersistent inhibitory circuit defects and disrupted social behaviour following in utero exogenous cannabinoid exposureA neuroligin-3 mutation implicated in autism causes abnormal aggression and increases repetitive behavior in miceAdvancing the understanding of autism disease mechanisms through geneticsThe interplay between synaptic activity and neuroligin function in the CNSCommon mechanisms of excitatory and inhibitory imbalance in schizophrenia and autism spectrum disordersInteraction between autism-linked MDGAs and neuroligins suppresses inhibitory synapse developmentGenetic targeting of NRXN2 in mice unveils role in excitatory cortical synapse function and social behaviorsFOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum DisordersSynaptic proteins and receptors defects in autism spectrum disordersAutism-related neuroligin-3 mutation alters social behavior and spatial learning.Lack of parvalbumin in mice leads to behavioral deficits relevant to all human autism core symptoms and related neural morphofunctional abnormalities.Mice with reduced NMDA receptor expression: more consistent with autism than schizophrenia?Neurexin and neuroligin mediate retrograde synaptic inhibition in C. elegans.Studying autism in rodent models: reconciling endophenotypes with comorbiditiesTowards identification of individual etiologies by resolving genomic and biological conundrums in patients with autism spectrum disorders.Translational animal models of autism and neurodevelopmental disorders.Genetic background modulates phenotypes of serotonin transporter Ala56 knock-in miceShank3-mutant mice lacking exon 9 show altered excitation/inhibition balance, enhanced rearing, and spatial memory deficit.Neurexins.Neuroimaging endophenotypes in animal models of autism spectrum disorders: lost or found in translation?Co-expression profiling of autism genes in the mouse brain.Open questions: what has genetics told us about autism spectrum disorders?Novel interactive partners of neuroligin 3: new aspects for pathogenesis of autism.
P2860
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P2860
Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Autism-linked neuroligin-3 R45 ...... and cortical synaptic function
@ast
Autism-linked neuroligin-3 R45 ...... and cortical synaptic function
@en
Autism-linked neuroligin-3 R45 ...... and cortical synaptic function
@nl
type
label
Autism-linked neuroligin-3 R45 ...... and cortical synaptic function
@ast
Autism-linked neuroligin-3 R45 ...... and cortical synaptic function
@en
Autism-linked neuroligin-3 R45 ...... and cortical synaptic function
@nl
prefLabel
Autism-linked neuroligin-3 R45 ...... and cortical synaptic function
@ast
Autism-linked neuroligin-3 R45 ...... and cortical synaptic function
@en
Autism-linked neuroligin-3 R45 ...... and cortical synaptic function
@nl
P2093
P2860
P3181
P356
P1476
Autism-linked neuroligin-3 R45 ...... and cortical synaptic function
@en
P2093
Csaba Földy
Katsuhiko Tabuchi
Manu Sharma
Mark Etherton
Mehrdad Shamloo
Xinran Liu
P2860
P304
P3181
P356
10.1073/PNAS.1111093108
P407
P577
2011-08-16T00:00:00Z