High throughput screening technologies for ion channels - Wikidata - awgldk - TriplyDB

High throughput screening technologies for ion channels

High throughput screening technologies for ion channels

http://www.wikidata.org/entity/Q26776486

about

Epigenetic assays for chemical biology and drug discovery.Optical electrophysiology for probing function and pharmacology of voltage-gated ion channels A new electro-optical approach for conductance measurement: an assay for the study of drugs acting on ligand-gated ion channels.High-Throughput Phenotyping of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Neurons Using Electric Field Stimulation and High-Speed Fluorescence Imaging.Bringing new dimensions to drug discovery screening: impact of cellular stimulation technologies.High-Content Assessment of Cardiac Function Using Heart-on-a-Chip Devices as Drug Screening Model.Development of Safe Drugs: The hERG Challenge.Ion channels research in the post-genomic era.Discovery and in Vitro Optimization of 3-Sulfamoylbenzamides as ROMK Inhibitors.Full-Spectral Multiplexing of Bioluminescence Resonance Energy Transfer in Three TRPV Channels.Enhancing inactivation rather than reducing activation of Nav1.7 channels by a clinically effective analgesic CNV1014802.Blocking mechanosensitive ion channels eliminates the effects of applied mechanical loading on chick joint morphogenesis

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High throughput screening technologies for ion channels

http://www.wikidata.org/entity/Q26776486

description

2016 nî lūn-bûn

@nan

2016 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2016 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

name

High throughput screening technologies for ion channels

@ast

High throughput screening technologies for ion channels

@en

High throughput screening technologies for ion channels

@nl

type

label

High throughput screening technologies for ion channels

@ast

High throughput screening technologies for ion channels

@en

High throughput screening technologies for ion channels

@nl

prefLabel

High throughput screening technologies for ion channels

@ast

High throughput screening technologies for ion channels

@en

High throughput screening technologies for ion channels

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High throughput screening technologies for ion channels

@en

P2093

Hai-bo Yu

http://www.w3.org/2001/XMLSchema#string

Min Li

http://www.w3.org/2001/XMLSchema#string

Wei-ping Wang

http://www.w3.org/2001/XMLSchema#string

Xiao-liang Wang

http://www.w3.org/2001/XMLSchema#string

P2860

Discovery of a series of 2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)acetamides as novel molecular switches that modulate modes of K(v)7.2 (KCNQ2) channel pharmacology: identification of (S)-2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)butanamide (ML252) as a po

Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator

Discovery, Synthesis, and Structure–Activity Relationship of a Series of N -Aryl-bicyclo[2.2.1]heptane-2-carboxamides: Characterization of ML213 as a Novel KCNQ2 and KCNQ4 Potassium Channel Opener

A new generation of Ca2+ indicators with greatly improved fluorescence properties

Yellow fluorescent protein-based assay to measure GABA(A) channel activation and allosteric modulation in CHO-K1 cells

Potent and selective inhibitors of the TASK-1 potassium channel through chemical optimization of a bis-amide scaffold.

Development and validation of fluorescence-based and automated patch clamp-based functional assays for the inward rectifier potassium channel Kir4.1.

Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds.

Mechanism and cellular applications of a green fluorescent protein-based halide sensor.

State-dependent compound inhibition of Nav1.2 sodium channels using the FLIPR Vm dye: on-target and off-target effects of diverse pharmacological agents.

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34-43

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1408852

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10.1038/APS.2015.108

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High-throughput screening

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