Translational challenges of animal models in Chagas disease drug development: a review

Translational challenges of animal models in Chagas disease drug development: a review

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http://www.wikidata.org/entity/Q26796451
Neglected tropical diseases in the genomics era: re-evaluating the impact of new drugs and mass drug administrationErgosterol isolated from the basidiomycete Pleurotus salmoneostramineus affects Trypanosoma cruzi plasma membrane and mitochondria.Cynomolgus macaques naturally infected with Trypanosoma cruzi-I exhibit an overall mixed pro-inflammatory/modulated cytokine signature characteristic of human Chagas diseaseClinical Candidate VT-1161's Antiparasitic Effect In Vitro, Activity in a Murine Model of Chagas Disease, and Structural Characterization in Complex with the Target Enzyme CYP51 from Trypanosoma cruzi.Nitroheterocyclic drugs cure experimental Trypanosoma cruzi infections more effectively in the chronic stage than in the acute stage.Chagas disease research and development: Is there light at the end of the tunnel?Putting Infection Dynamics at the Heart of Chagas Disease.A multi-parametric analysis of Trypanosoma cruzi infection: common pathophysiologic patterns beyond extreme heterogeneity of host responses.Use of Noninvasive Parameters to Evaluate Swiss Webster Mice During Trypanosoma cruzi Experimental Acute Infection.The Trypanocidal Effect of Novel Quinolines: In vitro And In vivo Studies.A novel nanoluciferase-based system to monitor Trypanosoma cruzi infection in mice by bioluminescence imaging.Repurposing Strategy of Atorvastatin against Trypanosoma cruzi: Monotherapy and Combined Therapy with Benznidazole Exhibit Synergistic Trypanocidal Activity
P2860

Translational challenges of animal models in Chagas disease drug development: a review

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http://www.wikidata.org/entity/Q26796451
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2015 թվականի օգոստոսին հրատարակված գիտական հոդված
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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Translational challenges of animal models in Chagas disease drug development: a review
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Translational challenges of animal models in Chagas disease drug development: a review
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Translational challenges of animal models in Chagas disease drug development: a review
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Translational challenges of animal models in Chagas disease drug development: a review
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Translational challenges of animal models in Chagas disease drug development: a review
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Translational challenges of animal models in Chagas disease drug development: a review
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Translational challenges of animal models in Chagas disease drug development: a review
@ast
Translational challenges of animal models in Chagas disease drug development: a review
@en
Translational challenges of animal models in Chagas disease drug development: a review
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Translational challenges of animal models in Chagas disease drug development: a review
@en
P2093
P275
P2860
P304
P31
P3181
P356
P407
P478
P5008
P577
P5875
P698
P921
P932