Structure-based methods for predicting target mutation-induced drug resistance and rational drug design to overcome the problem
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Reverse Chemical Genetics: Comprehensive Fitness Profiling Reveals the Spectrum of Drug Target InteractionsFast assessment of structural models of ion channels based on their predicted current-voltage characteristics.Protein design algorithms predict viable resistance to an experimental antifolateMechanistic insights into the substrate recognition of PPO: toward the rational design of effective inhibitorsEGFR Mutant Structural Database: computationally predicted 3D structures and the corresponding binding free energies with gefitinib and erlotinib.Identifying EGFR mutation-induced drug resistance based on alpha shape model analysis of the dynamicsPersonalized prediction of EGFR mutation-induced drug resistance in lung cancer.Progress in antiandrogen design targeting hormone binding pocket to circumvent mutation based resistanceEthyl 4-(4-methylphenyl)-4-pentenoate from Vetiveria zizanioides Inhibits Dengue NS2B-NS3 Protease and Prevents Viral Assembly: A Computational Molecular Dynamics and Docking Study.Quantum mechanics implementation in drug-design workflows: does it really help?Possible paths and potential barriers to successfully modeling drug resistance.Molecular Dynamics Validation of Crizotinib Resistance to ALK Mutations (L1196M and G1269A) and Identification of Specific Inhibitors.Computational design of novel inhibitors to overcome weed resistance associated with acetohydroxyacid synthase (AHAS) P197L mutant.
P2860
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P2860
Structure-based methods for predicting target mutation-induced drug resistance and rational drug design to overcome the problem
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Structure-based methods for pr ...... design to overcome the problem
@ast
Structure-based methods for pr ...... design to overcome the problem
@en
Structure-based methods for pr ...... design to overcome the problem
@nl
type
label
Structure-based methods for pr ...... design to overcome the problem
@ast
Structure-based methods for pr ...... design to overcome the problem
@en
Structure-based methods for pr ...... design to overcome the problem
@nl
prefLabel
Structure-based methods for pr ...... design to overcome the problem
@ast
Structure-based methods for pr ...... design to overcome the problem
@en
Structure-based methods for pr ...... design to overcome the problem
@nl
P2093
P2860
P3181
P1433
P1476
Structure-based methods for pr ...... design to overcome the problem
@en
P2093
Chang-Guo Zhan
Ge-Fei Hao
Guang-Fu Yang
P2860
P304
P3181
P356
10.1016/J.DRUDIS.2012.06.018
P407
P577
2012-10-01T00:00:00Z