Transient receptor potential channels as drug targets: from the science of basic research to the art of medicine
about
TRPV1: A Target for Rational Drug DesignTRP channels in schistosomesTRP Channels as Therapeutic Targets in Diabetes and ObesityEffect of capsaicin on thermoregulation: an update with new aspectsEvidence for Novel Pharmacological Sensitivities of Transient Receptor Potential (TRP) Channels in Schistosoma mansoniUpregulation of the transient receptor potential ankyrin 1 ion channel in the inflamed human and mouse colon and its protective rolesComparative genomics explains the evolutionary success of reef-forming coralsPurinergic and calcium signaling in macrophage function and plasticity.The Transient Receptor Potential (TRP) Channel Family in Colletotrichum graminicola: A Molecular and Physiological AnalysisDistinct modes of perimembrane TRP channel turnover revealed by TIR-FRAP.First-in-human phase I study of SOR-C13, a TRPV6 calcium channel inhibitor, in patients with advanced solid tumors.Classical Transient Receptor Potential 1 (TRPC1): Channel or Channel Regulator?Role of TRP channels in the cardiovascular system.Temperature oscillations drive cycles in the activity of MMP-2,9 secreted by a human trabecular meshwork cell line.Screening of Transient Receptor Potential Canonical Channel Activators Identifies Novel Neurotrophic Piperazine Compounds.Complementary roles of KCa3.1 channels and β1-integrin during alveolar epithelial repairGenetic deficit of KCa 3.1 channels protects against pulmonary circulatory collapse induced by TRPV4 channel activation.Meningeal transient receptor potential channel M8 activation causes cutaneous facial and hindpaw allodynia in a preclinical rodent model of headacheCapsaicin reduces Alzheimer-associated tau changes in the hippocampus of type 2 diabetes ratsVanilloids selectively sensitize thermal glutamate release from TRPV1 expressing solitary tract afferentsSelective Activation of Nociceptor TRPV1 Channel and Reversal of Inflammatory Pain in Mice by a Novel Coumarin Derivative Muralatin L from Murraya alataUnderstanding TRPV1 activation by ligands: Insights from the binding modes of capsaicin and resiniferatoxin.Proton-gated Ca(2+)-permeable TRP channels damage myelin in conditions mimicking ischaemia.Endothelial Dysfunction and Amyloid-β-Induced Neurovascular Alterations.Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis.Potential therapeutic value of TRPV1 and TRPA1 in diabetes mellitus and obesity.Natural killer cells and single nucleotide polymorphisms of specific ion channels and receptor genes in myalgic encephalomyelitis/chronic fatigue syndrome.Novel identification and characterisation of Transient receptor potential melastatin 3 ion channels on Natural Killer cells and B lymphocytes: effects on cell signalling in Chronic fatigue syndrome/Myalgic encephalomyelitis patients.Transient Receptor Potential Canonical (TRPC)/Orai1-dependent Store-operated Ca2+ Channels: NEW TARGETS OF ALDOSTERONE IN CARDIOMYOCYTES.Targeting TRP channels for chronic cough: from bench to bedside.Transient receptor potential ankyrin 1 (TRPA1) antagonists.Capsaicin may have important potential for promoting vascular and metabolic health.Transient Receptor Potential (TRP) channels in T cells.Genetic variants affecting human TRPA1 or TRPM8 structure can be classified in vitro as 'well expressed', 'poorly expressed' or 'salvageable'.Feeling hot, feeling cold: TRP channels-a great story unfoldsFunctional expression of TRPV channels in T cells and their implications in immune regulation.Marine Cyclic Guanidine Alkaloids Monanchomycalin B and Urupocidin A Act as Inhibitors of TRPV1, TRPV2 and TRPV3, but not TRPA1 Receptors.Challenges to develop novel anti-inflammatory and analgesic drugs.Medicinal Chemistry, Pharmacology, and Clinical Implications of TRPV1 Receptor Antagonists.Crosstalk between calcium and reactive oxygen species signaling in cancer.
P2860
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P2860
Transient receptor potential channels as drug targets: from the science of basic research to the art of medicine
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Transient receptor potential c ...... esearch to the art of medicine
@ast
Transient receptor potential c ...... esearch to the art of medicine
@en
Transient receptor potential c ...... esearch to the art of medicine
@nl
type
label
Transient receptor potential c ...... esearch to the art of medicine
@ast
Transient receptor potential c ...... esearch to the art of medicine
@en
Transient receptor potential c ...... esearch to the art of medicine
@nl
prefLabel
Transient receptor potential c ...... esearch to the art of medicine
@ast
Transient receptor potential c ...... esearch to the art of medicine
@en
Transient receptor potential c ...... esearch to the art of medicine
@nl
P3181
P356
P1476
Transient receptor potential c ...... esearch to the art of medicine
@en
P2093
A. Szallasi
P304
P3181
P356
10.1124/PR.113.008268
P407
P577
2014-07-01T00:00:00Z