Evolution and dynamics of pancreatic cancer progression - Wikidata - awgldk - TriplyDB

Evolution and dynamics of pancreatic cancer progression

Evolution and dynamics of pancreatic cancer progression

http://www.wikidata.org/entity/Q26849671

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Pancreatic Cancer Metabolism: Breaking It Down to Build It Back Up Pancreatic adenocarcinoma pathology: changing "landscape"Nonequilibrium population dynamics of phenotype conversion of cancer cells Single-cell genome sequencing: current state of the science.CDK4/6 inhibitors have potent activity in combination with pathway selective therapeutic agents in models of pancreatic cancer.Disease pathways at the Rat Genome Database Pathway Portal: genes in context-a network approach to understanding the molecular mechanisms of disease.Pancreatic cancer genomics: where can the science take us?Targeting the mRNA-binding protein HuR impairs malignant characteristics of pancreatic ductal adenocarcinoma cells Novel approaches in the management of pancreatic ductal adenocarcinoma: potential promises for the future.Process of hepatic metastasis from pancreatic cancer: biology with clinical significance.Subclonal diversification of primary breast cancer revealed by multiregion sequencing.An angiopoietin-like protein 2 autocrine signaling promotes EMT during pancreatic ductal carcinogenesis.Animal Models of Gastrointestinal and Liver Diseases. The difficulty of animal modeling of pancreatic cancer for preclinical evaluation of therapeutics.A MEK/PI3K/HDAC inhibitor combination therapy for KRAS mutant pancreatic cancer cells.The evolution of tumor metastasis during clonal expansion with alterations in metastasis driver genes CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma Genetic Diversity of Pancreatic Ductal Adenocarcinoma and Opportunities for Precision Medicine Identifying the clonal origin of synchronous multifocal tumors in the hepatobiliary and pancreatic system using multi-omic platforms.Gene expression profiling of patient-derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ1: implications for individualized medicine efforts Emerging role of the KRAS-PDK1 axis in pancreatic cancer.Gemcitabine resistant pancreatic cancer cell lines acquire an invasive phenotype with collateral hypersensitivity to histone deacetylase inhibitors.Catalog of genetic progression of human cancers: breast cancer.Diagnostic value of selected markers and apoptotic pathways for pancreatic cancer.Leveraging Mechanisms Governing Pancreatic Tumorigenesis To Reduce Pancreatic Cancer Mortality.Pancreatic Ductal Adenocarcinoma: Current and Evolving Therapies.Neuroendocrine carcinoma of the pancreas with similar genetic alterations to invasive ductal adenocarcinoma.Acinar-to-Ductal Metaplasia Induced by Transforming Growth Factor Beta Facilitates KRASG12D-driven Pancreatic Tumorigenesis.Germline factor DDX4 functions in blood-derived cancer cell phenotypes.PCMdb: pancreatic cancer methylation database.Phenotypic changes of acid-adapted cancer cells push them toward aggressiveness in their evolution in the tumor microenvironment.Disconnect between EMT and metastasis in pancreas cancer Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer - Early Results from the COMPASS Trial.EVI1 modulates oncogenic role of GPC1 in pancreatic carcinogenesis.Long-term patterns of fasting blood glucose levels and pancreatic cancer incidence.Safety signal detection and evaluation in clinical development programs: A case study of tofacitinib.Proteomic Analysis of Combined Gemcitabine and Birinapant in Pancreatic Cancer Cells.Mutant p53 Together with TGFβ Signaling Influence Organ-Specific Hematogenous Colonization Patterns of Pancreatic Cancer.Association between CLPTM1L-TERT rs401681 polymorphism and risk of pancreatic cancer: a meta-analysis.Evolution of features of chronic pancreatitis during endoscopic ultrasound-based surveillance of individuals at high risk for pancreatic cancer.Impact of p53 and PDGFR-β Expression on Metastasis and Prognosis of Patients with Pancreatic Cancer.

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Evolution and dynamics of pancreatic cancer progression

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C A Iacobuzio-Donahue

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P2860

Hallmarks of Cancer: The Next Generation

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis.

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer

The epithelial-mesenchymal transition generates cells with properties of stem cells

Cancer-stromal cell interactions mediated by hypoxia-inducible factors promote angiogenesis, lymphangiogenesis, and metastasis

The SMAD4 protein and prognosis of pancreatic ductal adenocarcinoma.

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10.1038/ONC.2013.29

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