The overlooked greatwall: a new perspective on mitotic control
about
MASTL(Greatwall) regulates DNA damage responses by coordinating mitotic entry after checkpoint recovery and APC/C activationBudding yeast greatwall and endosulfines control activity and spatial regulation of PP2A(Cdc55) for timely mitotic progression.Mastl is required for timely activation of APC/C in meiosis I and Cdk1 reactivation in meiosis IICdc25A activity is required for the metaphase II arrest in mouse oocytes.Cell cycle regulation of Greatwall kinase nuclear localization facilitates mitotic progressionGreatwall is essential to prevent mitotic collapse after nuclear envelope breakdown in mammals.α-endosulfine (ENSA) regulates exit from prophase I arrest in mouse oocytesCentrosomes as signalling centres.EphrinB1: novel microtubule associated protein whose expression affects taxane sensitivityDual targeting of microtubule and topoisomerase II by α-carboline derivative YCH337 for tumor proliferation and growth inhibition.Inhibitory Role of Greatwall-Like Protein Kinase Rim15p in Alcoholic Fermentation via Upregulating the UDP-Glucose Synthesis Pathway in Saccharomyces cerevisiae.Binding of Drosophila Polo kinase to its regulator Matrimony is noncanonical and involves two separate functional domains.Working hard for recovery: mitotic kinases in the DNA damage checkpointThe phosphorylation of ARPP19 by Greatwall renders the auto-amplification of MPF independently of PKA in Xenopus oocytes.Greatwall-phosphorylated Endosulfine is both an inhibitor and a substrate of PP2A-B55 heterotrimers.Reciprocal regulation of ARPP-16 by PKA and MAST3 kinases provides a cAMP-regulated switch in protein phosphatase 2A inhibition.Measuring time during early embryonic development.Timing the Drosophila Mid-Blastula Transition: A Cell Cycle-Centered View.Profiling DNA damage response following mitotic perturbations.A PP2A-B55 recognition signal controls substrate dephosphorylation kinetics during mitotic exit.The BEG (PP2A-B55/ENSA/Greatwall) pathway ensures cytokinesis follows chromosome separationThe cell cycle switch computes approximate majority.Therapeutic relevance of the PP2A-B55 inhibitory kinase MASTL/Greatwall in breast cancer.A Role for the Twins Protein Phosphatase (PP2A-B55) in the Maintenance of Drosophila Genome Integrity.Cell cycle-dependent regulation of Greatwall kinase by protein phosphatase 1 and regulatory subunit 3B.Preparing a cell for nuclear envelope breakdown: Spatio-temporal control of phosphorylation during mitotic entry.
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P2860
The overlooked greatwall: a new perspective on mitotic control
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2012 թուականի Մարտին հրատարակուած գիտական յօդուած
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2012 թվականի մարտին հրատարակված գիտական հոդված
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2012年の論文
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2012年論文
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The overlooked greatwall: a new perspective on mitotic control
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The overlooked greatwall: a new perspective on mitotic control
@en
The overlooked greatwall: a new perspective on mitotic control
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label
The overlooked greatwall: a new perspective on mitotic control
@ast
The overlooked greatwall: a new perspective on mitotic control
@en
The overlooked greatwall: a new perspective on mitotic control
@nl
prefLabel
The overlooked greatwall: a new perspective on mitotic control
@ast
The overlooked greatwall: a new perspective on mitotic control
@en
The overlooked greatwall: a new perspective on mitotic control
@nl
P2860
P921
P356
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P1476
The overlooked greatwall: a new perspective on mitotic control
@en
P2093
D. M. Glover
P2860
P304
P356
10.1098/RSOB.120023
P407
P577
2012-03-01T00:00:00Z