Merging molecular mechanism and evolution: theory and computation at the interface of biophysics and evolutionary population genetics
about
Decoding mechanisms by which silent codon changes influence protein biogenesis and functionWhat can we learn from fitness landscapes?Potts Hamiltonian models of protein co-variation, free energy landscapes, and evolutionary fitness.Biophysical Models of Protein Evolution: Understanding the Patterns of Evolutionary Sequence Divergence.The Role of Evolutionary Selection in the Dynamics of Protein Structure Evolution.Reconstructed Ancestral Enzymes Impose a Fitness Cost upon Modern Bacteria Despite Exhibiting Favourable Biochemical Properties.Coevolutionary Landscape Inference and the Context-Dependence of Mutations in Beta-Lactamase TEM-1.Thermal stabilization of dihydrofolate reductase using monte carlo unfolding simulations and its functional consequences.Protein Homeostasis Imposes a Barrier on Functional Integration of Horizontally Transferred Genes in BacteriaProteome Evolution of Deep-Sea Hydrothermal Vent Alvinellid Polychaetes Supports the Ancestry of Thermophily and Subsequent Adaptation to Cold in Some Lineages.Monod-Wyman-Changeux Analysis of Ligand-Gated Ion Channel Mutants.Bridging the physical scales in evolutionary biology: from protein sequence space to fitness of organisms and populations.Evolutionary dynamics of viral escape under antibodies stress: A biophysical model.A "fuzzy"-logic language for encoding multiple physical traits in biomolecules.Stability of the Influenza Virus Hemagglutinin Protein Correlates with Evolutionary Dynamics.Substitution rates predicted by stability-constrained models of protein evolution are not consistent with empirical data.Selecting among three basic fitness landscape models: Additive, multiplicative and stickbreaking.Multisequence algorithm for coarse-grained biomolecular simulations: Exploring the sequence-structure relationship of proteins.Beyond Thermodynamic Constraints: Evolutionary Sampling Generates Realistic Protein Sequence Variation.Hsp90 shapes protein and RNA evolution to balance trade-offs between protein stability and aggregation.Optimization of lag phase shapes the evolution of a bacterial enzyme.Predicting evolution.Hidden long evolutionary memory in a model biochemical network.Influence of mutation bias and hydrophobicity on the substitution rates and sequence entropies of protein evolutionSelection for Protein Stability Enriches for Epistatic Interactions
P2860
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P2860
Merging molecular mechanism and evolution: theory and computation at the interface of biophysics and evolutionary population genetics
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Merging molecular mechanism an ...... olutionary population genetics
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Merging molecular mechanism an ...... olutionary population genetics
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Merging molecular mechanism an ...... olutionary population genetics
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type
label
Merging molecular mechanism an ...... olutionary population genetics
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Merging molecular mechanism an ...... olutionary population genetics
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Merging molecular mechanism an ...... olutionary population genetics
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prefLabel
Merging molecular mechanism an ...... olutionary population genetics
@ast
Merging molecular mechanism an ...... olutionary population genetics
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Merging molecular mechanism an ...... olutionary population genetics
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P2860
P1476
Merging molecular mechanism an ...... olutionary population genetics
@en
P2093
Adrian WR Serohijos
P2860
P356
10.1016/J.SBI.2014.05.005
P407
P577
2014-06-01T00:00:00Z