Expanding P450 catalytic reaction space through evolution and engineering
about
Versatile biocatalysis of fungal cytochrome P450 monooxygenasesAccessing Nature's diversity through metabolic engineering and synthetic biologyAdvances in the directed evolution of proteins.Dynamically achieved active site precision in enzyme catalysisUnraveling the Transcriptional Basis of Temperature-Dependent Pinoxaden Resistance in Brachypodium hybridum.Characterization of non-heme iron aliphatic halogenase WelO5* fromHapalosiphon welwitschiiIC-52-3: Identification of a minimal protein sequence motif that confers enzymatic chlorination specificity in the biosynthesis of welwitindolelinones.Enantioselective imidation of sulfides via enzyme-catalyzed intermolecular nitrogen-atom transferP450-catalyzed asymmetric cyclopropanation of electron-deficient olefins under aerobic conditions.Enzyme-controlled nitrogen-atom transfer enables regiodivergent C-H amination.Expanding the enzyme universe: accessing non-natural reactions by mechanism-guided directed evolution.Directed Evolution of Enzymes for Industrial Biocatalysis.Enantioselective Enzyme-Catalyzed Aziridination Enabled by Active-Site Evolution of a Cytochrome P450Engineered P450 biocatalysts show improved activity and regio-promiscuity in aromatic nitration.Keeping the spotlight on cytochrome P450.Methane-Oxidizing Enzymes: An Upstream Problem in Biological Gas-to-Liquids Conversion.Guidelines for development and implementation of biocatalytic P450 processes.Current advances in the novel functions of hypoxia-inducible factor and prolyl hydroxylase in invertebrates.The nature of chemical innovation: new enzymes by evolution.Genetic Optimization of Metalloenzymes: Enhancing Enzymes for Non-Natural Reactions.Improving artificial metalloenzymes' activity by optimizing electron transfer.Spectroscopic studies of the cytochrome P450 reaction mechanisms.Aliphatic Halogenase Enables Late-Stage C-H Functionalization: Selective Synthesis of a Brominated Fischerindole Alkaloid with Enhanced Antibacterial Activity.The Oxidation of Hydrophobic Aromatic Substrates by Using a Variant of the P450 Monooxygenase CYP101B1.Identification of the Biosynthetic Pathway for the Antibiotic Bicyclomycin.Selective oxidation of aliphatic C-H bonds in alkylphenols by a chemomimetic biocatalytic system.P450 BM3-Catalyzed Regio- and Stereoselective Hydroxylation Aiming at the Synthesis of Phthalides and Isocoumarins.Biocatalysis in the Pharmaceutical Industry: The Need for Speed.An artificial self-sufficient cytochrome P450 directly nitrates fluorinated tryptophan analogs with a different regio-selectivity.One-Pot Biocatalytic Double Oxidation of α-Isophorone for the Synthesis of KetoisophoroneA hydroquinone-specific screening system for directed P450 evolution
P2860
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P2860
Expanding P450 catalytic reaction space through evolution and engineering
description
2014 nî lūn-bûn
@nan
2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Expanding P450 catalytic reaction space through evolution and engineering
@ast
Expanding P450 catalytic reaction space through evolution and engineering
@en
Expanding P450 catalytic reaction space through evolution and engineering
@nl
type
label
Expanding P450 catalytic reaction space through evolution and engineering
@ast
Expanding P450 catalytic reaction space through evolution and engineering
@en
Expanding P450 catalytic reaction space through evolution and engineering
@nl
prefLabel
Expanding P450 catalytic reaction space through evolution and engineering
@ast
Expanding P450 catalytic reaction space through evolution and engineering
@en
Expanding P450 catalytic reaction space through evolution and engineering
@nl
P2860
P3181
P1476
Expanding P450 catalytic reaction space through evolution and engineering
@en
P2093
Christopher C Farwell
John A McIntosh
P2860
P304
P3181
P356
10.1016/J.CBPA.2014.02.001
P407
P577
2014-04-01T00:00:00Z