Translation regulation as a therapeutic target in cancer
about
Functional Integration of mRNA Translational Control ProgramsTargeting translation initiation in breast cancerTwo complementary approaches for intracellular delivery of exogenous enzymes.Identification of phenotype-relevant differentially expressed genes in breast cancer demonstrates enhanced quantile discretization protocol's utility in multi-platform microarray data integration.The translation elongation factor eEF2 is a novel tumor‑associated antigen overexpressed in various types of cancers.Systematic genomic and translational efficiency studies of uveal melanoma.Somatic cells regulate maternal mRNA translation and developmental competence of mouse oocytesHeterocyclic aminoparthenolide derivatives modulate G(2)-M cell cycle progression during Xenopus oocyte maturation.Flavaglines target primitive leukemia cells and enhance anti-leukemia drug activity.A hypusine-eIF5A-PEAK1 switch regulates the pathogenesis of pancreatic cancerTranslation initiation complex eIF4F is a therapeutic target for dual mTOR kinase inhibitors in non-Hodgkin lymphoma.Biological Relevance and Therapeutic Potential of the Hypusine Modification System.The eIF3 complex of Leishmania-subunit composition and mode of recruitment to different cap-binding complexes.Computational discovery of pathway-level genetic vulnerabilities in non-small-cell lung cancer.Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1Dual modulation of Ras-Mnk and PI3K-AKT-mTOR pathways: A Novel c-FLIP inhibitory mechanism of 3-AWA mediated translational attenuation through dephosphorylation of eIF4E.Translating mRNAs strongly correlate to proteins in a multivariate manner and their translation ratios are phenotype specific.A combination of temsirolimus, an allosteric mTOR inhibitor, with clofarabine as a new therapeutic option for patients with acute myeloid leukemiaProtein phosphatase PPM1G regulates protein translation and cell growth by dephosphorylating 4E binding protein 1 (4E-BP1)Altered splicing leads to reduced activation of CPEB3 in high-grade gliomas.MNK1 pathway activity maintains protein synthesis in rapalog-treated gliomas.Elevated eukaryotic elongation factor 2 expression is involved in proliferation and invasion of lung squamous cell carcinomaTranslational control of the fibroblast-extracellular matrix association: An application to pulmonary fibrosis.Transcriptome and long noncoding RNA sequencing of three extracellular vesicle subtypes released from the human colon cancer LIM1863 cell line.Translational compensation of genomic instability in neuroblastomaMolecular mechanisms of mTOR regulation by stressRepression of microRNA-768-3p by MEK/ERK signalling contributes to enhanced mRNA translation in human melanoma.Evasion of regulatory phosphorylation by an alternatively spliced isoform of Musashi2.Prediction of mycoplasma hominis proteins targeting in mitochondria and cytoplasm of host cells and their implication in prostate cancer etiology.Clinicopathological sex- related relevance of musashi1 mRNA expression in esophageal squamous cell carcinoma patients.Identification of cellular genes and pathways important for tumorigenicity of hepatocellular carcinoma cell lines by proteomic profiling.Pre-45s rRNA promotes colon cancer and is associated with poor survival of CRC patients.Eukaryotic Elongation Factor 2 (eEF2) is a Potential Biomarker of Prostate Cancer.Computational resources for ribosome profiling: from database to Web server and software.AMP Kinase Activation Alters Oxidant-Induced Stress Granule Assembly by Modulating Cell Signaling and Microtubule OrganizationA census of human RNA-binding proteinsTranslation acrobatics: how cancer cells exploit alternate modes of translational initiation
P2860
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P2860
Translation regulation as a therapeutic target in cancer
description
2012 nî lūn-bûn
@nan
2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Translation regulation as a therapeutic target in cancer
@ast
Translation regulation as a therapeutic target in cancer
@en
Translation regulation as a therapeutic target in cancer
@nl
type
label
Translation regulation as a therapeutic target in cancer
@ast
Translation regulation as a therapeutic target in cancer
@en
Translation regulation as a therapeutic target in cancer
@nl
prefLabel
Translation regulation as a therapeutic target in cancer
@ast
Translation regulation as a therapeutic target in cancer
@en
Translation regulation as a therapeutic target in cancer
@nl
P3181
P1433
P1476
Translation regulation as a therapeutic target in cancer
@en
P2093
B. A. Hemmings
P304
P3181
P356
10.1158/0008-5472.CAN-12-0026
P407
P577
2012-08-15T00:00:00Z