Autophagy modulation as a potential therapeutic target for diverse diseases - Wikidata - awgldk - TriplyDB

Autophagy modulation as a potential therapeutic target for diverse diseases

Autophagy modulation as a potential therapeutic target for diverse diseases

http://www.wikidata.org/entity/Q27010076

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Architecture and dynamics of the autophagic phosphatidylinositol 3-kinase complex Modulation of deregulated chaperone-mediated autophagy by a phosphopeptide Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity Intracellular targeting with engineered proteins Metabolic, autophagic, and mitophagic activities in cancer initiation and progression The autophagy-lysosomal system in subarachnoid haemorrhage New Potential Pharmacological Functions of Chinese Herbal Medicines via Regulation of Autophagy Modulation of Host Autophagy during Bacterial Infection: Sabotaging Host Munitions for Pathogen Nutrition The Autophagic Machinery in Enterovirus Infection Autophagy in colorectal cancer: An important switch from physiology to pathology Mitochondria-Associated Endoplasmic Reticulum Membranes Microenvironment: Targeting Autophagic and Apoptotic Pathways in Cancer Therapy The role of perlecan and endorepellin in the control of tumor angiogenesis and endothelial cell autophagy Interactions between Autophagy and Bacterial Toxins: Targets for Therapy?Development of autophagy inducers in clinical medicine Chloroquine and hydroxychloroquine for cancer therapy Autophagy paradox and ceramide Transgenic animal models for study of the pathogenesis of Huntington's disease and therapy The interplay of reovirus with autophagy Wip1 phosphatase: between p53 and MAPK kinases pathways Autophagy and apoptosis in liver injury Autophagy and regulation of cilia function and assembly Autophagy and neurodegeneration Mechanisms and models of endoplasmic reticulum stress in chondrodysplasia Autophagy in malignant transformation and cancer progression Therapeutic targeting of autophagy in neurodegenerative and infectious diseases Nonprofessional phagocytic cell receptors involved in Staphylococcus aureus internalization Autophagy modulation as a target for anticancer drug discovery Disruption in connexin-based communication is associated with intracellular Ca²⁺ signal alterations in astrocytes from Niemann-Pick type C mice Aberrant autolysosomal regulation is linked to the induction of embryonic senescence: differential roles of Beclin 1 and p53 in vertebrate Spns1 deficiency Human A53T α-synuclein causes reversible deficits in mitochondrial function and dynamics in primary mouse cortical neurons Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy Therapeutic Targeting of Autophagy Cellular proteostasis: degradation of misfolded proteins by lysosomes The role of STAT3 in autophagy Autophagy regulates sphingolipid levels in the liver Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway New insights into TB physiology suggest untapped therapeutic opportunities

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Autophagy modulation as a potential therapeutic target for diverse diseases

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2012 nî lūn-bûn

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2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Autophagy modulation as a potential therapeutic target for diverse diseases

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Autophagy modulation as a potential therapeutic target for diverse diseases

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Autophagy modulation as a potential therapeutic target for diverse diseases

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type

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Autophagy modulation as a potential therapeutic target for diverse diseases

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Autophagy modulation as a potential therapeutic target for diverse diseases

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Autophagy modulation as a potential therapeutic target for diverse diseases

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prefLabel

Autophagy modulation as a potential therapeutic target for diverse diseases

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Autophagy modulation as a potential therapeutic target for diverse diseases

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Autophagy modulation as a potential therapeutic target for diverse diseases

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Nature Reviews Drug Discovery

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Autophagy modulation as a potential therapeutic target for diverse diseases

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David C. Rubinsztein

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P2860

Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains

Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein

Image-based genome-wide siRNA screen identifies selective autophagy factors

ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1

Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription

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