Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions - Wikidata - awgldk - TriplyDB

Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions

Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions

http://www.wikidata.org/entity/Q27025786

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ATR-mediated regulation of nuclear and cellular plasticity ATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to Adaptor Oxidative stress, bone marrow failure, and genome instability in hematopoietic stem cells Nucleotide salvage deficiencies, DNA damage and neurodegeneration Molecular and Functional Characterization of a Cohort of Spanish Patients with Ataxia-Telangiectasia Deficient expression of aldehyde dehydrogenase 1A1 is consistent with increased sensitivity of Gorlin syndrome patients to radiation carcinogenesis Melanocytes and their diseases Ataxia Telangiectasia-Mutated (ATM)Polymorphisms and Risk of Lung Cancer in a Chinese Population Induction of ATM/ATR pathway combined with Vγ2Vδ2 T cells enhances cytotoxicity of ovarian cancer cells The ataxia telangiectasia mutated and cyclin D3 proteins cooperate to help enforce TCRβ and IgH allelic exclusion ATM gene mutations in sporadic breast cancer patients from Brazil.Receptor tyrosine kinase EphA5 is a functional molecular target in human lung cancer Body composition, muscle strength and hormonal status in patients with ataxia telangiectasia: a cohort study.Oxidative Stress in Cancer-Prone Genetic Diseases in Pediatric Age: The Role of Mitochondrial Dysfunction Proinflammatory genotype is associated with the frailty phenotype in the English Longitudinal Study of Ageing.Ataxia-Pancytopenia Syndrome Is Caused by Missense Mutations in SAMD9L.DNA repair pathways underlie a common genetic mechanism modulating onset in polyglutamine diseases Overproduction of reactive oxygen species - obligatory or not for induction of apoptosis by anticancer drugs ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia.The Aspergillus nidulans ATM kinase regulates mitochondrial function, glucose uptake and the carbon starvation response.Functional overlaps between XLF and the ATM-dependent DNA double strand break response.Functional interplay between ATM/ATR-mediated DNA damage response and DNA repair pathways in oxidative stress.miR-214: a potential biomarker and therapeutic for different cancers.ATM protein kinase signaling, type 2 diabetes and cardiovascular disease.Live longer on MARS: a yeast paradigm of mitochondrial adaptive ROS signaling in aging.Dexamethasone improves redox state in ataxia telangiectasia cells by promoting an NRF2-mediated antioxidant response.Clinicopathological significance of ATM-Chk2 expression in sporadic breast cancers: a comprehensive analysis in large cohorts.Mutation of ataxia-telangiectasia mutated is associated with dysfunctional glutathione homeostasis in cerebellar astroglia.Modulation of inflammation and disease tolerance by DNA damage response pathways.Oxidative stress, mitochondrial abnormalities and antioxidant defense in Ataxia-telangiectasia, Bloom syndrome and Nijmegen breakage syndrome.Neurodegeneration in ataxia-telangiectasia: Multiple roles of ATM kinase in cellular homeostasis.Recent advances in the study of immunodeficiency and DNA damage response.The clinical significance of complete class switching defect in Ataxia telangiectasia patients.Noninfectious Granulomas: A Sign of an Underlying Immunodeficiency?Targeting the Ataxia Telangiectasia Mutated-null phenotype in chronic lymphocytic leukemia with pro-oxidants.Is age a risk factor for liver disease and metabolic alterations in ataxia Telangiectasia patients?Polymorphism rs189037C > T in the promoter region of the ATM gene may associate with reduced risk of T2DM in older adults in China: a case control study.Manganese superoxide dismutase from human pathogen Clostridium difficile.Modulation of proteostasis counteracts oxidative stress and affects DNA base excision repair capacity in ATM-deficient cells.Oxidative stress as a therapeutic perspective for ATM-deficient chronic lymphocytic leukemia patients.

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Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions

http://www.wikidata.org/entity/Q27025786

description

2013 nî lūn-bûn

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2013 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2013 թվականի մայիսին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions

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Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions

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Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions

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type

label

Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions

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Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions

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Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions

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Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions

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Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions

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Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions

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Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions

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M. Ambrose

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R. A. Gatti

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P2860

Role of AMP-activated protein kinase in mechanism of metformin action

SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

Direct regulation of CREB transcriptional activity by ATM in response to genotoxic stress

Hypoxia-inducible factors and the response to hypoxic stress

Mitochondrial dysfunction in ataxia-telangiectasia

Mutations in PNKP cause microcephaly, seizures and defects in DNA repair

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

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