about
Functional coupling of TRPV4 cationic channel and large conductance, calcium-dependent potassium channel in human bronchial epithelial cell linesIP3 receptor binds to and sensitizes TRPV4 channel to osmotic stimuli via a calmodulin-binding site.An environmental sensor, TRPV4 is a novel regulator of intracellular Ca2+ in human synoviocytes.The progesterone receptor regulates the expression of TRPV4 channel.Tyrosine phosphorylation modulates the activity of TRPV4 in response to defined stimuli.Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice.TRPV channels and modulation by hepatocyte growth factor/scatter factor in human hepatoblastoma (HepG2) cells.Evidence for a functional role of endothelial transient receptor potential V4 in shear stress-induced vasodilatation.Calcium-dependent signalling is essential during collateral growth in the pig hind limb-ischemia model.Involvement of TRPV4-NO-cGMP-PKG pathways in the development of thermal hyperalgesia following chronic compression of the dorsal root ganglion in rats.Cardiac fibroblasts have functional TRPV4 activated by 4alpha-phorbol 12,13-didecanoate.Activity of protein kinase C modulates the apoptosis induced by polychlorinated biphenyls in human leukemic HL-60 cells.Modulation of Ca2+-activated K+ channels of human erythrocytes by endogenous protein kinase C.Trpv4 induces collateral vessel growth during regeneration of the arterial circulation.ATP-sensitive K+ channels in pig urethral smooth muscle cells are heteromultimers of Kir6.1 and Kir6.2.TRPV4-like non-selective cation currents in cultured aortic myocytes.A transient receptor potential vanilloid 4 contributes to mechanical allodynia following chronic compression of dorsal root ganglion in rats.High D-glucose reduces SLC29A1 promoter activity and adenosine transport involving specific protein 1 in human umbilical vein endothelium.Antidipsogenic effects of a TRPV4 agonist, 4alpha-phorbol 12,13-didecanoate, injected into the cerebroventricle.Activation of urothelial transient receptor potential vanilloid 4 by 4alpha-phorbol 12,13-didecanoate contributes to altered bladder reflexes in the rat.PLA2 and TRPV4 channels regulate endothelial calcium in cerebral arteries.A novel function of capsaicin-sensitive TRPV1 channels: involvement in cell migrationTRPV4 as a flow sensor in flow-dependent K+ secretion from the cortical collecting duct
P921
Q24310055-5CAEF670-62AE-4D71-BB3C-4606867E16E9Q34841332-107958AA-7ECE-463F-A2C7-A0FF5F837104Q39798688-20D2F16B-96A7-4615-8317-AA9052EA4977Q39809253-292669E0-7CB6-42DD-A0AD-B0784E399B19Q39912354-81300587-ADAD-462C-B7A7-24A29A6E0F56Q40204850-B7126FB8-B0FC-4E68-AF93-333CFED212C9Q40559355-D7FC5798-2991-4BD7-B5B6-89DF10D46EE6Q42494772-726DDFDB-1233-4C1B-8972-14B4267FD302Q43110513-65302FB1-1A81-4027-8C5A-615760C7C248Q43233574-16A4A257-9FA0-4A2A-A616-06315B1B94D3Q43251247-B49C38FE-E4EF-4EBD-B894-3BED95D02CDCQ44146863-12F5D4A2-B8BA-44CE-9D90-3F83C17B64BDQ44428952-32F406CF-2B7A-44D6-8537-6D4F7FEB43CEQ46239842-DDCA87B1-FE0A-4267-88EB-FBA8D19ACE50Q46302072-8FADE51A-8243-443F-B287-A3D7042CB8E5Q46322735-59259869-0460-40B9-8FF5-72E932CB91EAQ46800297-37CC5423-53B8-4CDB-A3AD-D6D09A23CDB5Q46862162-F32D6D47-11C0-4593-AC90-DAF29C52BCDDQ46913743-4DE2A302-4E9E-4E18-A8CA-5212F1775926Q48582426-A04117E9-FB44-42A2-A6CD-C28B21D67B0EQ50716747-4B5A7A17-120F-432F-9151-9EE52F3D67CFQ79447400-78FFADC2-8762-4D2B-B2A1-BE8C5AE169D0Q80216378-A22A6ADE-F168-4671-94D6-02A5A2144C61
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
4α-PDD
@en
type
label
4α-PDD
@en
altLabel
4alpha-phorbol-didecanoate
@en
4α-phorbol 12,13-didecanoate
@en
prefLabel
4α-PDD
@en
P592
P661
P662
P683
P2017
CCCCCCCCCC(=O)O[C@@H]1[C@H]([C ...... @]1(C4(C)C)OC(=O)CCCCCCCCC)O)C
P2067
672.460119
P233
CCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)CCCCCCCCC)O)C
P234
1S/C40H64O8/c1-7-9-11-13-15-17 ...... ,31-,34-,36-,38+,39-,40-/m1/s1
P235
DGOSGFYDFDYMCW-OEFRVDPMSA-N
P274
P592
CHEMBL118987