about
Biological characterization of AT7519, a small-molecule inhibitor of cyclin-dependent kinases, in human tumor cell lines.Biased and unbiased strategies to identify biologically active small molecules.Cyclin-Dependent Kinase Inhibitor AT7519 as a Potential Drug for MYCN-Dependent NeuroblastomaA phase I pharmacokinetic and pharmacodynamic study of AT7519, a cyclin-dependent kinase inhibitor in patients with refractory solid tumors.AT7519, A novel small molecule multi-cyclin-dependent kinase inhibitor, induces apoptosis in multiple myeloma via GSK-3beta activation and RNA polymerase II inhibition.Anticancer and radiosensitizing effects of the cyclin-dependent kinase inhibitors, AT7519 and SNS‑032, on cervical cancer
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
at-7519
@en
type
label
at-7519
@en
altLabel
4-{[(2,6-dichlorophenyl)carbonyl]amino}-N-piperidin-4-yl-1H-pyrazole-3-carboxamide
@en
AT 7519
@en
AT7519
@en
prefLabel
at-7519
@en
P592
P638
P661
P662
P683
P2067
P231
844442-38-2
P233
C1CNCCC1NC(=O)C2=C(C=NN2)NC(=O)C3=C(C=CC=C3Cl)Cl
P234
1S/C16H17Cl2N5O2/c17-10-2-1-3- ...... H2,(H,20,23)(H,21,25)(H,22,24)
P235
OVPNQJVDAFNBDN-UHFFFAOYSA-N
P274
C₁₆H₁₇Cl₂N₅O₂
P3117
DTXSID30233420
P592
CHEMBL445813
P652
X1BF92PW9T