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Molecular characterization of acquired tolerance of tumor cells to picropodophyllin (PPP)Expression and effects of inhibition of type I insulin-like growth factor receptor tyrosine kinase in mantle cell lymphoma.The association of TP53 mutations with the resistance of colorectal carcinoma to the insulin-like growth factor-1 receptor inhibitor picropodophyllin.Potent inhibitory effect of the cyclolignan picropodophyllin (PPP) on human adrenocortical carcinoma cells proliferation.Multiple antitumor effects of picropodophyllin in colon carcinoma cell lines: clinical implications.Picropodophyllin inhibits the growth of Ewing's sarcoma cells through the insulin‑like growth factor‑1 receptor/Akt signaling pathway.Picropodophyllin inhibits proliferation and survival of diffuse large B-cell lymphoma cells.Targeting the insulin-like growth factor-1 receptor by picropodophyllin for lung cancer chemoprevention.The insulin-like growth factor-I receptor inhibitor picropodophyllin-induced selective apoptosis of hepatocellular carcinoma cell through a caspase-dependent mitochondrial pathway.Abnormal expression of insulin-like growth factor-I receptor in hepatoma tissue and its inhibition to promote apoptosis of tumor cells.Heterogeneity of neuroblastoma cell lines in insulin-like growth factor 1 receptor/Akt pathway-mediated cell proliferative responses.Alternative cytotoxic effects of the postulated IGF-IR inhibitor picropodophyllin in vitro.Picropodophyllin inhibits epithelial ovarian cancer cells in vitro and in vivo.Investigating new therapeutic strategies targeting hyperinsulinemia's mitogenic effects in a female mouse breast cancer model.Effects of epidermal growth factor receptor and insulin-like growth factor 1 receptor inhibition on proliferation and intracellular signaling in cutaneous SCCHN: potential for dual inhibition as a therapeutic modality.The HDAC inhibitor LBH589 enhances the antimyeloma effects of the IGF-1RTK inhibitor picropodophyllin.The insulin receptor/insulin-like growth factor receptor family as a therapeutic target in oncology.Targeting the insulin-like growth factor-1 receptor by picropodophyllin as a treatment option for glioblastoma.Novel biotransformation process of podophyllotoxin to produce podophyllic acid and picropodophyllotoxin by Pseudomonas aeruginosa CCTCC AB93066. Part I: process development.Novel biotransformation process of podophyllotoxin to produce podophyllic acid and picropodophyllotoxin by Pseudomonas aeruginosa CCTCC AB93066, part II: process optimization.Epigenetic modification after inhibition of IGF-1R signaling in human central nervous system atypical teratoid rhabdoid tumor (AT/RT).Determination of picropodophyllin and its isomer podophyllotoxin in human serum samples with electrospray ionization of hexylamine adducts by liquid chromatography-tandem mass spectrometry
P921
Q28741971-13F9E92E-6E9D-4BEE-BC93-4CE8466E119AQ35018535-B3A5D059-EAB1-40FD-8B5C-CEF743F26BD7Q35030616-3E322B3E-8FC7-42EA-B654-17C0AA61FAA8Q35232280-81CA93F1-751D-4BE3-9497-12544F7632C2Q36645661-1B3267F1-FF10-4000-B513-D68E63CDF2DEQ38839345-4BD794E5-243B-4B79-85AD-3CBE1A9486D9Q38869967-9CA1E038-7756-478B-94E5-9500188A47E0Q38962349-D158DDCE-C74E-4240-909B-5EE9A17001DCQ39036005-A1CAD962-26A5-46F0-B296-61F71E1E0E35Q39135542-42E16701-64D5-46A1-9A64-4BCA9E40A25BQ39147077-383ABC3F-DC32-453A-90A0-DF5DCCD993AEQ39148452-7DD4D28F-8571-400D-B0A7-739144AE1829Q39153421-610609C1-0327-4060-90FF-AEFC6D2656BCQ39177951-47447C81-8B79-47BD-ADC9-6BF6B9CC6B0EQ39365739-FCA08471-77CF-4372-888F-4EBB6932A62FQ39384823-E2EE148D-4652-4169-B9C5-CF1668F9B236Q39668060-AB30A2A6-3504-4537-A27F-B67097677749Q39740608-5C0A3861-8B43-4438-AE54-7DB1BB18FBCFQ46179906-AE03FCBE-8347-42AF-B4CA-ED451F960DCEQ46205871-CF11D0A3-8ED8-4327-BE5D-4E41C933809AQ46523458-EBE4E088-9D3B-447C-B6E7-208F72BAECBEQ83252682-D8B30E56-F981-4AE2-AB74-BFC27089BBBE
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
picropodophyllin
@en
type
label
picropodophyllin
@en
altLabel
(5R,5aS,8aR,9R)-5,8,8a,9-Tetra ...... o[2,3-d]-1,3-dioxol-6(5aH)-one
@en
AXL1717
@en
Picropodophyllin
@en
Picropodophyllotoxin
@en
podofilox
@en
prefLabel
picropodophyllin
@en
P592
P661
P662
P665
P683
P1579
P2017
COC1=CC(=CC(=C1OC)OC)[C@H]2[C@H]3[C@H](COC3=O)[C@H](C4=CC5=C(C=C24)OCO5)O
P2057
HMDB0031452
P2064
P2067
P231
P232
P233
COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O
P234
1S/C22H22O8/c1-25-16-4-10(5-17 ...... 2,1-3H3/t13-,18+,19+,20-/m0/s1
P235
YJGVMLPVUAXIQN-HAEOHBJNSA-N
P2566
100.164.896
P274
P2840
P3117
DTXSID80197245