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Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cellsInfluence of the 5-HT(2C) receptor antagonist SB242,084 on behaviour produced by the 5-HT(2) agonist Ro60-0175 and the indirect 5-HT agonist dexfenfluramineThe serotonin 2C receptor agonist Ro-60-0175 attenuates effects of nicotine in the five-choice serial reaction time task and in drug discriminationNeuroendocrine evidence that (S)-2-(chloro-5-fluoro-indol- l-yl)-1-methylethylamine fumarate (Ro 60-0175) is not a selective 5-hydroxytryptamine(2C) receptor agonist.The 5-HT2C receptor agonist Ro60-0175 reduces cocaine self-administration and reinstatement induced by the stressor yohimbine, and contextual cues.5-HT2C receptor agonists: pharmacological characteristics and therapeutic potential.Comparative effects of continuous infusion of mCPP, Ro 60-0175 and d-fenfluramine on food intake, water intake, body weight and locomotor activity in rats.The enhanced oral response to the 5-HT2 agonist Ro 60-0175 in parkinsonian rats involves the entopeduncular nucleus: electrophysiological correlates.Biochemical and electrophysiological evidence that RO 60-0175 inhibits mesolimbic dopaminergic function through serotonin(2C) receptors.Antagonizing 5-HT₂A receptors with M100907 and stimulating 5-HT₂C receptors with Ro60-0175 blocks cocaine-induced locomotion and zif268 mRNA expression in Sprague-Dawley rats.Injection of the 5-HT2C receptor agonist Ro60-0175 into the ventral tegmental area reduces cocaine-induced locomotor activity and cocaine self-administration.Effects of the 5-HT2C receptor agonist Ro60-0175 and the 5-HT2A receptor antagonist M100907 on nicotine self-administration and reinstatement.Increased temporal discounting after chronic stress in CHL1-deficient mice is reversed by 5-HT2C agonist Ro 60-0175.Discriminative stimulus properties of the novel serotonin (5-HT)2C receptor agonist, RO 60-0175: a pharmacological analysis.Similarities in the action of Ro 60-0175, a 5-HT2C receptor agonist, and d-fenfluramine on feeding patterns in the rat8-OH-DPAT-induced spontaneous tail-flicks in the rat are facilitated by the selective serotonin (5-HT)2C agonist, RO 60-0175: blockade of its actions by the novel 5-HT2C receptor antagonist SB 206,553
P921
Q24675490-22879CC9-4CEF-462A-B1F0-B1DBBD19066DQ28366550-4597F921-5E02-4DB3-A80E-0723E57BF999Q28576908-EB24D0AC-D26F-408F-9A70-720D16B11921Q34179708-BB570DB0-7F11-4EAB-B587-9D4CCB543CC7Q34655896-95BD321B-116A-4CD9-8F6D-364402749415Q34750267-3C74BF28-ECAE-430A-83D7-A40C5A94054EQ41835936-D0FB802A-CFD1-432C-8DAA-14CA3EB466F2Q42436356-9892835C-C7B2-4431-A511-E588450B8B1CQ42488122-1DCDE057-FE8A-47EB-BF16-44D6936B2DF2Q44443195-998048B2-8712-4384-9C64-D5A534DA006DQ44686785-F9B84477-7094-497B-BFDC-74BD0402E152Q48655865-0ADA6DAC-3D4E-4444-9FB4-3317D3A2B21BQ50580794-2F2158A0-F36F-4F4B-89DA-0CC81EF7EC3AQ52177592-AD38F796-9164-45B9-9F41-A8EB3360305EQ60054744-084197D4-9071-4BE7-9EDA-87A1C0CF71D8Q73514603-43B1F293-B36D-4EF5-B2FC-05E018B12112
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
Ro 60-0175
@en
type
label
Ro 60-0175
@en
altLabel
Ro-600175
@en
Ro600175
@en
prefLabel
Ro 60-0175
@en
P592
P661
P662
P683
P2017
C[C@@H](CN1C=CC2=CC(=C(C=C21)Cl)F)N
P2067
226.067304
P233
CC(CN1C=CC2=CC(=C(C=C21)Cl)F)N
P234
1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3/t7-/m0/s1
P235
XJJZQXUGLLXTHO-ZETCQYMHSA-N
P274
C₁₁H₁₂ClFN₂
P592
CHEMBL76781