about
Oxidized phospholipids in minimally modified low density lipoprotein induce apoptotic signaling via activation of acid sphingomyelinase in arterial smooth muscle cellsOxidized phospholipid species promote in vivo differential cx43 phosphorylation and vascular smooth muscle cell proliferationImport and fate of fluorescent analogs of oxidized phospholipids in vascular smooth muscle cells.Structurally similar oxidized phospholipids differentially regulate endothelial binding of monocytes and neutrophils.Short-term stimulation of calcium-permeable transient receptor potential canonical 5-containing channels by oxidized phospholipids.The oxidized phospholipids POVPC and PGPC inhibit growth and induce apoptosis in vascular smooth muscle cells.Oxidation changes physical properties of phospholipid bilayers: fluorescence spectroscopy and molecular simulations.Temporary membrane distortion of vascular smooth muscle cells is responsible for their apoptosis induced by platelet-activating factor-like oxidized phospholipids and their degradation product, lysophosphatidylcholine.Determinants of bioactivity of oxidized phospholipids. Specific oxidized fatty acyl groups at the sn-2 position.
P921
Q28565237-5835D118-33FF-4B51-97A6-9A384477BD29Q30435253-26FFD395-733F-4CA5-A0BD-76AA9E3F29F2Q33265039-D5D5E069-86CC-480F-B323-6F3A73368246Q35730371-E3448EB8-180F-4C8F-B16B-E6712605BCA3Q39716991-97EF4E5E-6597-424D-AB99-41B36217F4C0Q40244459-4BD35CFB-F48C-4C31-BB48-D8E3FB8C272BQ43101520-4653D772-81AB-47F4-9725-559EF88D4F58Q44633314-45100C72-E103-470A-B6CB-55D3D8ACF9F7Q46706472-7BFF9CE2-7C13-42E0-9A3D-4C80723BF5B2
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
2-O-glutaroyl-1-O-palmitoyl-sn-glycero-3-phosphocholine
@en
type
label
2-O-glutaroyl-1-O-palmitoyl-sn-glycero-3-phosphocholine
@en
altLabel
1-O-palmitoyl-2-O-glutaroyl-sn-glycero-3-phosphocholine
@en
1-O-palmitoyl-2-O-glutaryl-sn-glycero-3-phosphocholine
@en
1-palmitoyl-2-glutaroyl-sn-glycero-3-phosphocholine
@en
1-palmitoyl-2-glutaryl-glycerophosphocholine
@en
1-palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine
@en
2-O-glutaryl-1-O-palmitoyl-sn-glycero-3-phosphocholine
@en
PGPC
@en
prefLabel
2-O-glutaroyl-1-O-palmitoyl-sn-glycero-3-phosphocholine
@en
P661
P662
P683
P1579
P2017
CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCC(=O)O
P2063
LMGP20010006
P2067
609.364184
P231
89947-79-5
P233
CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCC(=O)O
P234
1S/C29H56NO10P/c1-5-6-7-8-9-10 ...... H3,(H-,31,32,35,36)/t26-/m1/s1
P235
CDZVJFRXJAUXPP-AREMUKBSSA-N
P274
C₂₉H₅₆NO₁₀P
P3117
DTXSID50677185