sameAs
An LC/MS method for the quantitative determination of 7alpha-OH DHEA and 7beta-OH DHEA: an application for the study of the metabolism of DHEA in rat brain.CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation by proinflammatory cytokines.Dehydroepiandrosterone and its metabolites: differential effects on androgen receptor trafficking and transcriptional activity.Dehydroepiandrosterone 7alpha-hydroxylation in human tissues: possible interference with type 1 11beta-hydroxysteroid dehydrogenase-mediated processes.The native anti-glucocorticoid paradigm.Inter-conversion of 7alpha- and 7beta-hydroxy-dehydroepiandrosterone by the human 11beta-hydroxysteroid dehydrogenase type 1.Selective conversion by microglia of dehydroepiandrosterone to 5-androstenediol-A steroid with inherent estrogenic properties.DHEA metabolism in arthritis: a role for the p450 enzyme Cyp7b at the immune-endocrine crossroad.Effects of CYP7B1-mediated catalysis on estrogen receptor activation.The 7-hydroxylation of dehydroepiandrosterone in rat brain.In vitro metabolism of dehydroepiandrosterone (DHEA) to 7alpha-hydroxy-DHEA and Delta5-androstene-3beta,17beta-diol in specific regions of the aging brain from Alzheimer's and non-demented patients.Stereo- and regioselectivity account for the diversity of dehydroepiandrosterone (DHEA) metabolites produced by liver microsomal cytochromes P450.Antioxidant effects of dehydroepiandrosterone and 7alpha-hydroxy-dehydroepiandrosterone in the rat colon, intestine and liver.Severity of murine collagen-induced arthritis correlates with increased CYP7B activity: enhancement of dehydroepiandrosterone metabolism by interleukin-1beta.Simultaneous determination of dehydroepiandrosterone and its 7-oxygenated metabolites in human serum by high-resolution gas chromatography--mass spectrometry.Dehydroepiandrosterone and its 7-hydroxylated metabolites do not interfere with the transactivation and cellular trafficking of the glucocorticoid receptor.Neurosteroids: metabolism in human intestine microsomes.7beta-Hydroxy-epiandrosterone-mediated regulation of the prostaglandin synthesis pathway in human peripheral blood monocytes.Protection against dextran sodium sulfate-induced colitis by dehydroepiandrosterone and 7alpha-hydroxy-dehydroepiandrosterone in the rat.Changes to fetal steroidogenesis caused by maternal smoking.Dehydroepiandrosterone metabolites and their interactions in humans.Steroid hormones and homocysteine in the outcome of patients with normal pressure hydrocephalus.Steroid hormones related to 11beta-hydroxysteroid dehydrogenase type 1 in treated obesity.
P921
Q33520025-5E1358F1-0F04-41E7-BDCD-090E27503053Q34400590-EB6E5503-5124-454B-B8E0-15C58A3793C2Q34500451-F57F5588-0357-4BD1-83F1-81CFCE4205B1Q34623841-0E491DDD-F242-4611-8449-CE3F30E214CCQ36483410-FB7EE825-FEA6-4A94-B306-359F271540E7Q39751173-36B1E0FD-36BC-43B3-8C20-D53E2D655B20Q40097373-B271987E-CEEB-4E3F-932A-FE5A96DA4C57Q40253436-1C14D867-B2CA-40D8-8AC7-4C3F169A4422Q43017806-85461A3E-B053-41E7-8D03-88047CD9FD5BQ43163215-1A94D47B-EBA5-4221-8564-65661EC8BCB2Q44390926-D9592FB8-41AE-45B5-BDE3-967D5770529FQ44772645-3285649E-E096-40E4-92B0-BEFC2817CCB4Q44795096-2683EDC1-D810-4CBC-99B0-732EF429D5D8Q45099958-9585A245-7C33-48EC-885E-0D7494728B1AQ45176161-A7D1DE51-30C4-468F-BCC3-4DA98FE314DBQ45255560-201DEB34-2128-411E-A7E8-8C32C5AF8FEAQ46397972-C3264E9F-9F09-4882-B3EC-D37B8B36EDEDQ46538955-549E6233-F4F0-45A4-B970-7D98E11AC39DQ46863196-E344766E-E2A7-483B-A0E7-5D3CD10B912BQ47628194-B6D179C6-FDCA-466E-ACCB-7B1EA88E66CBQ48345016-01EEADE5-8A87-4A97-A3B1-50FA259F7ED7Q48707254-2AA2B98C-47C5-4754-9B5D-0166A36963B8Q53648843-26852D8D-93DE-411C-8A70-CE2267167BC8
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
7α-hydroxydehydroepiandrosterone
@en
type
label
7α-hydroxydehydroepiandrosterone
@en
altLabel
3beta,7alpha-Dihydroxy-5-androstene-17-one
@en
3β,7α-dihydroxyandrost-4-ene-17-one
@en
7alpha-OH-DHEA
@en
7α-hydroxy-DHEA
@en
prefLabel
7α-hydroxydehydroepiandrosterone
@en
P592
P661
P662
P665
P683
P2017
C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)[C@@H](C=C4[C@@]3(CC[C@@H](C4)O)C)O
P2063
LMST02020101
P2067
P231
P233
CC12CCC3C(C1CCC2=O)C(C=C4C3(CCC(C4)O)C)O
P234
1S/C19H28O3/c1-18-7-5-12(20)9- ...... ,13-,14-,15+,17-,18-,19-/m0/s1
P235
OLPSAOWBSPXZEA-JIEICEMKSA-N
P274
P592
CHEMBL1079392
P652
CL15H93XTM