about
Growth inhibition with reversible cell cycle arrest of carcinoma cells by flavone L86-8275Flavopiridol (L86 8275; NSC 649890), a new kinase inhibitor for tumor therapy.Antitumoral activity of flavone L-86-8275.Flavopiridol (L86-8275): selective antitumor activity in vitro and activity in vivo for prostate carcinoma cells.Potent inhibition of CDC2 kinase activity by the flavonoid L86-8275.Alteration of the phosphorylation state of p34cdc2 kinase by the flavone L86-8275 in breast carcinoma cells. Correlation with decreased H1 kinase activity.Cytotoxic synergy between flavopiridol (NSC 649890, L86-8275) and various antineoplastic agents: the importance of sequence of administration
P921
Q28342649-A3352E84-A4F9-48E5-B415-DAF1861110F1Q33889556-3B1FBAA7-49E4-4748-97E8-E9FE9CC31C79Q33893972-02D01ADC-A393-4879-8348-759BB7D9C5D4Q41128761-1D76A58D-8311-4E26-B5E8-AE6A3DBB7592Q42283108-FCD9FD9D-4807-443E-A223-C41E4E632262Q42286823-97E53DE4-AE50-473D-86AC-9AB668B4FF34Q58290188-7B1ED690-B69D-4E29-A579-D06A1AA2A1C0
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
alvocidib hydrochloride
@en
type
label
alvocidib hydrochloride
@en
altLabel
(3S,4R)-4-[2-(2-chlorophenyl)- ...... -1-methylpiperidinium chloride
@en
HL 275
@en
HL-275
@en
HMR 1275
@en
HMR-1275
@en
L 86 8275
@en
L86-8275
@en
alvocidib HCl
@en
prefLabel
alvocidib hydrochloride
@en
P592
P661
P662
P665
P683
P2017
CN1CC[C@@H]([C@@H](C1)O)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O.Cl
P2067
P231
131740-09-5
P232
P233
CN1CCC(C(C1)O)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O.Cl
P234
1S/C21H20ClNO5.ClH/c1-23-7-6-1 ...... 7,10H2,1H3;1H/t12-,17+;/m0./s1
P235
LGMSNQNWOCSPIK-LWHGMNCYSA-N
P2566
100.162.335
P274
C₂₁H₂₁Cl₂NO₅
P2840
P3117
DTXSID6048961
P592
CHEMBL2105698
P652
D48MS3A6N9