Effective gene therapy in a mouse model of prion diseases

Effective gene therapy in a mouse model of prion diseases

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http://www.wikidata.org/entity/Q27300832
The glial response to intracerebrally delivered therapies for neurodegenerative disorders: is this a critical issue?Treatment of Prion Disease with Heterologous Prion ProteinsFeline immunodeficiency virus as a gene transfer vector in the rat nucleus tractus solitariiDominant prion mutants induce curing through pathways that promote chaperone-mediated disaggregation.Systemic delivery of siRNA down regulates brain prion protein and ameliorates neuropathology in prion disorder.Insights into prion biology: integrating a protein misfolding pathway with its cellular environment.A naturally occurring C-terminal fragment of the prion protein (PrP) delays disease and acts as a dominant-negative inhibitor of PrPSc formation.A Fluorescent Oligothiophene-Bis-Triazine ligand interacts with PrP fibrils and detects SDS-resistant oligomers in human prion diseases.Heterozygous inhibition in prion infection: the stone fence modelTherapeutic interventions ameliorating prion disease.Prion diseases and adult neurogenesis: how do prions counteract the brain's endogenous repair machinery?Potential approaches for heterologous prion protein treatment of prion diseases.Manganese chelation therapy extends survival in a mouse model of M1000 prion disease.A dominant-negative mutant inhibits multiple prion variants through a common mechanism.Low doses of bioherbicide favour prion aggregation and propagation in vivo.
P2860

Effective gene therapy in a mouse model of prion diseases

Item
http://www.wikidata.org/entity/Q27300832
description
2008 nî lūn-bûn
@nan
2008 թուականին հրատարակուած գիտական յօդուած
@hyw
2008 թվականին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Effective gene therapy in a mouse model of prion diseases
@ast
Effective gene therapy in a mouse model of prion diseases
@en
Effective gene therapy in a mouse model of prion diseases
@nl
type
label
Effective gene therapy in a mouse model of prion diseases
@ast
Effective gene therapy in a mouse model of prion diseases
@en
Effective gene therapy in a mouse model of prion diseases
@nl
prefLabel
Effective gene therapy in a mouse model of prion diseases
@ast
Effective gene therapy in a mouse model of prion diseases
@en
Effective gene therapy in a mouse model of prion diseases
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
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P433
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P5875
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P1476
Effective gene therapy in a mouse model of prion diseases
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0002773
P407
P433
P478
P50
P577
P5875
P698
P921
P932