Expanded GAA repeats impair FXN gene expression and reposition the FXN locus to the nuclear lamina in single cells - Wikidata - awgldk - TriplyDB

Expanded GAA repeats impair FXN gene expression and reposition the FXN locus to the nuclear lamina in single cells

Expanded GAA repeats impair FXN gene expression and reposition the FXN locus to the nuclear lamina in single cells

http://www.wikidata.org/entity/Q27301037

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Reversal of epigenetic promoter silencing in Friedreich ataxia by a class I histone deacetylase inhibitor.Stalled DNA Replication Forks at the Endogenous GAA Repeats Drive Repeat Expansion in Friedreich's Ataxia Cells.RNA activation of haploinsufficient Foxg1 gene in murine neocortex.Emerging therapies in Friedreich's ataxia.Friedreich Ataxia: current status and future prospects.The Replication of Frataxin Gene Is Assured by Activation of Dormant Origins in the Presence of a GAA-Repeat Expansion.Enhancing Neuronogenesis and Counteracting Neuropathogenic Gene Haploinsufficiencies by RNA Gene Activation.Increased Frataxin Expression Induced in Friedreich Ataxia Cells by Platinum TALE-VP64s or Platinum TALE-SunTag.

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Expanded GAA repeats impair FXN gene expression and reposition the FXN locus to the nuclear lamina in single cells

http://www.wikidata.org/entity/Q27301037

description

2015 nî lūn-bûn

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2015 թուականի Մարտին հրատարակուած գիտական յօդուած

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2015 թվականի մարտին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

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2015年論文

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2015年论文

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name

Expanded GAA repeats impair FX ...... nuclear lamina in single cells

@ast

Expanded GAA repeats impair FX ...... nuclear lamina in single cells

@en

Expanded GAA repeats impair FX ...... nuclear lamina in single cells

@nl

type

label

Expanded GAA repeats impair FX ...... nuclear lamina in single cells

@ast

Expanded GAA repeats impair FX ...... nuclear lamina in single cells

@en

Expanded GAA repeats impair FX ...... nuclear lamina in single cells

@nl

prefLabel

Expanded GAA repeats impair FX ...... nuclear lamina in single cells

@ast

Expanded GAA repeats impair FX ...... nuclear lamina in single cells

@en

Expanded GAA repeats impair FX ...... nuclear lamina in single cells

@nl

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Human Molecular Genetics

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Expanded GAA repeats impair FX ...... nuclear lamina in single cells

@en

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Ana M Silva

http://www.w3.org/2001/XMLSchema#string

Jill M Brown

http://www.w3.org/2001/XMLSchema#string

Michele M P Lufino

http://www.w3.org/2001/XMLSchema#string

Veronica J Buckle

http://www.w3.org/2001/XMLSchema#string

P2860

The GAA triplet-repeat expansion in Friedreich ataxia interferes with transcription and may be associated with an unusual DNA structure

Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription

Hyperexpansion of GAA repeats affects post-initiation steps of FXN transcription in Friedreich's ataxia

Nuclear neighborhoods and gene expression

Clustering of multiple specific genes and gene-rich R-bands around SC-35 domains: evidence for local euchromatic neighborhoods

Building a nuclear envelope at the end of mitosis: coordinating membrane reorganization, nuclear pore complex assembly, and chromatin de-condensation

Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brain

Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation

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3457-3471

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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4443713

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10.1093/HMG/DDV096

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12

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24

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2015-03-26T00:00:00Z

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25814655

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4498154

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