Mutant huntingtin downregulates myelin regulatory factor-mediated myelin gene expression and affects mature oligodendrocytes
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Microglial Activation in the Pathogenesis of Huntington's Disease.Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease.Compartment-Dependent Degradation of Mutant Huntingtin Accounts for Its Preferential Accumulation in Neuronal ProcessesFrequency of nuclear mutant huntingtin inclusion formation in neurons and glia is cell-type-specific.Structural and molecular myelination deficits occur prior to neuronal loss in the YAC128 and BACHD models of Huntington disease.Insights into mechanisms of central nervous system myelination using zebrafish.Inherited and acquired disorders of myelin: The underlying myelin pathology.Drug discovery for remyelination and treatment of MS.Impaired Levels of Gangliosides in the Corpus Callosum of Huntington Disease Animal ModelsCell and Context-Dependent Effects of the Heat Shock Protein DNAJB6 on Neuronal Survival.Postnatal and adult consequences of loss of huntingtin during development: Implications for Huntington's disease.Mutant Huntingtin Inhibits αB-Crystallin Expression and Impairs Exosome Secretion from Astrocytes.Phagocytic Roles of Glial Cells in Healthy and Diseased Brains.Comparison of spinocerebellar ataxia type 3 mouse models identifies early gain-of-function, cell-autonomous transcriptional changes in oligodendrocytes.Synergistic Toxicity of Polyglutamine-Expanded TATA-Binding Protein in Glia and Neuronal Cells: Therapeutic Implications for Spinocerebellar Ataxia 17.Natural variation in sensory-motor white matter organization influences manifestations of Huntington's disease.The Leukocentric Theory of Neurological Disorder: A Manifesto.Molecular insights into cortico-striatal miscommunications in Huntington's disease.Reactive Neuroblastosis in Huntington's Disease: A Putative Therapeutic Target for Striatal Regeneration in the Adult Brain.Imaging Myelination In Vivo Using Transparent Animal Models.Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease.An automated high-resolution in vivo screen in zebrafish to identify chemical regulators of myelinationThe Role of Adenosine Tone and Adenosine Receptors in Huntington's Disease
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P2860
Mutant huntingtin downregulates myelin regulatory factor-mediated myelin gene expression and affects mature oligodendrocytes
description
2015 nî lūn-bûn
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2015 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մարտին հրատարակված գիտական հոդված
@hy
2015年の論文
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2015年論文
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2015年論文
@zh-hant
2015年論文
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2015年論文
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2015年論文
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2015年论文
@wuu
name
Mutant huntingtin downregulate ...... ffects mature oligodendrocytes
@ast
Mutant huntingtin downregulate ...... ffects mature oligodendrocytes
@en
Mutant huntingtin downregulate ...... ffects mature oligodendrocytes
@nl
type
label
Mutant huntingtin downregulate ...... ffects mature oligodendrocytes
@ast
Mutant huntingtin downregulate ...... ffects mature oligodendrocytes
@en
Mutant huntingtin downregulate ...... ffects mature oligodendrocytes
@nl
prefLabel
Mutant huntingtin downregulate ...... ffects mature oligodendrocytes
@ast
Mutant huntingtin downregulate ...... ffects mature oligodendrocytes
@en
Mutant huntingtin downregulate ...... ffects mature oligodendrocytes
@nl
P2093
P2860
P3181
P1433
P1476
Mutant huntingtin downregulate ...... ffects mature oligodendrocytes
@en
P2093
Brenda Huang
Guohao Wang
Marta A Gaertig
WenJie Wei
Xiao-Jiang Li
P2860
P304
P3181
P356
10.1016/J.NEURON.2015.02.026
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P50
P577
2015-03-01T00:00:00Z