In silico analysis of conformational changes induced by mutation of aromatic binding residues: consequences for drug binding in the hERG K+ channel
about
Translational toxicology and rescue strategies of the hERG channel dysfunction: biochemical and molecular mechanistic aspectsProbing the energy landscape of activation gating of the bacterial potassium channel KcsAExploring the structure of the voltage-gated Na+ channel by an engineered drug access pathway to the receptor site for local anesthetics.Modeling and simulation of ion channels.ICA-105574 interacts with a common binding site to elicit opposite effects on inactivation gating of EAG and ERG potassium channels.Drug trapping in hERG K+ channels: (not) a matter of drug size?Assessing hERG pore models as templates for drug docking using published experimental constraints: the inactivated state in the context of drug block.Molecular Mechanisms of Crude Oil Developmental Toxicity in Fish.Structure-activity relationships of pentamidine-affected ion channel trafficking and dofetilide mediated rescue.Probing the molecular basis of hERG drug block with unnatural amino acids.In silico design of novel hERG-neutral sildenafil-like PDE5 inhibitors.
P2860
Q27008208-160096B6-97A1-4E54-A9A5-37F81F2B4EAFQ28487458-ECD49440-1BE6-43E5-A4FF-C3905902AA25Q30363787-D2D9AB6C-66AF-49CF-AD68-CD3EA161093FQ30443341-CE2EB747-BB0D-4F5A-A492-CFA2B3B1C4ACQ36717056-19A65C82-C880-4246-A1AE-0F4AF73B6894Q37626136-5EC286DF-67F6-43CE-BC9B-5D12D76A6911Q38632776-6BD63591-E0B7-4F9B-8C3E-C459C947BFDDQ39427481-E65C9207-77B1-4B9C-8B51-2016D7D91DDCQ39435268-51213169-B6F4-4A29-B096-5A80D95FB7B7Q48267422-2277A966-1926-444D-8FBF-CF33CCB99E92Q50627316-5105F5CB-9446-4947-836E-6167A8E29E7B
P2860
In silico analysis of conformational changes induced by mutation of aromatic binding residues: consequences for drug binding in the hERG K+ channel
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
@hyw
2011 թվականին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
In silico analysis of conforma ...... binding in the hERG K+ channel
@ast
In silico analysis of conforma ...... binding in the hERG K+ channel
@en
In silico analysis of conforma ...... binding in the hERG K+ channel
@nl
type
label
In silico analysis of conforma ...... binding in the hERG K+ channel
@ast
In silico analysis of conforma ...... binding in the hERG K+ channel
@en
In silico analysis of conforma ...... binding in the hERG K+ channel
@nl
prefLabel
In silico analysis of conforma ...... binding in the hERG K+ channel
@ast
In silico analysis of conforma ...... binding in the hERG K+ channel
@en
In silico analysis of conforma ...... binding in the hERG K+ channel
@nl
P2093
P2860
P1433
P1476
In silico analysis of conforma ...... binding in the hERG K+ channel
@en
P2093
Anna Stary-Weinzinger
Anton Beyer
Kirsten Knape
Peter Wolschann
P2860
P304
P356
10.1371/JOURNAL.PONE.0028778
P407
P577
2011-01-01T00:00:00Z