Siglec-1 is a novel dendritic cell receptor that mediates HIV-1 trans-infection through recognition of viral membrane gangliosides
about
Blocking HIV-1 transmission in the female reproductive tract: from microbicide development to exploring local antiviral responsesExosomes: Implications in HIV-1 PathogenesisIntravital microscopy in BLT-humanized mice to study cellular dynamics in HIV infectionCD169-dependent cell-associated HIV-1 transmission: a driver of virus disseminationDressing up Nanoparticles: A Membrane Wrap to Induce Formation of the Virological Synapse.CD169-mediated trafficking of HIV to plasma membrane invaginations in dendritic cells attenuates efficacy of anti-gp120 broadly neutralizing antibodiesPolyICLC Exerts Pro- and Anti-HIV Effects on the DC-T Cell Milieu In Vitro and In VivoRetroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection.Deciphering the glycolipid code of Alzheimer's and Parkinson's amyloid proteins allowed the creation of a universal ganglioside-binding peptideGlycosphingolipid-functionalized nanoparticles recapitulate CD169-dependent HIV-1 uptake and trafficking in dendritic cellsVirus particle release from glycosphingolipid-enriched microdomains is essential for dendritic cell-mediated capture and transfer of HIV-1 and henipavirus.The interplay between Siglecs and sialylated pathogensSiglec-mediated regulation of immune cell function in disease.Lassa and Marburg viruses elicit distinct host transcriptional responses early after infection.Development of a recombinant antibody to target peptides and proteins to sialoadhesin-expressing macrophages.HIV-1 immune activation induces Siglec-1 expression and enhances viral trans-infection in blood and tissue myeloid cells.Interferon-inducible mechanism of dendritic cell-mediated HIV-1 dissemination is dependent on Siglec-1/CD169.HIV-1 capture and transmission by dendritic cells: the role of viral glycolipids and the cellular receptor Siglec-1Biological properties of extracellular vesicles and their physiological functions.Vpx-Independent Lentiviral Transduction and shRNA-Mediated Protein Knock-Down in Monocyte-Derived Dendritic Cells.Human Blood-Circulating Basophils Capture HIV-1 and Mediate Viral trans-Infection of CD4+ T Cells.Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1.Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells.Antiviral mechanism of polyanionic carbosilane dendrimers against HIV-1.Lipid-Mediated Targeting with Membrane-Wrapped Nanoparticles in the Presence of Corona FormationImmortalized MH-S cells lack defining features of primary alveolar macrophages and do not support mouse pneumovirus replication.Extracellular Vesicles Exploit Viral Entry Routes for Cargo Delivery.Human DC-SIGN binds specific human milk glycans.Human Immunodeficiency Virus Immune Cell Receptors, Coreceptors, and Cofactors: Implications for Prevention and Treatment.Effect of cytokines on Siglec-1 and HIV-1 entry in monocyte-derived macrophages: the importance of HIV-1 envelope V1V2 regionIdentification of Siglec-1 null individuals infected with HIV-1.Cell-Free versus Cell-to-Cell Infection by Human Immunodeficiency Virus Type 1 and Human T-Lymphotropic Virus Type 1: Exploring the Link among Viral Source, Viral Trafficking, and Viral Replication.Neutralizing IgG at the portal of infection mediates protection against vaginal simian/human immunodeficiency virus challengeNonhuman TRIM5 Variants Enhance Recognition of HIV-1-Infected Cells by CD8+ T Cells.HIV-1 Trans Infection of CD4(+) T Cells by Professional Antigen Presenting CellsDendritic cells: a spot on sialic Acid.Sialic acid-binding Ig-like lectin-7 interacts with HIV-1 gp120 and facilitates infection of CD4pos T cells and macrophages.Proteoliposomal formulations of an HIV-1 gp41-based miniprotein elicit a lipid-dependent immunodominant response overlapping the 2F5 binding motif.Host Immune Responses in HIV-1 Infection: The Emerging Pathogenic Role of Siglecs and Their Clinical Correlates.Contributions of HIV-1 Nef to immune dysregulation in HIV-infected patients: a therapeutic target?
P2860
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P2860
Siglec-1 is a novel dendritic cell receptor that mediates HIV-1 trans-infection through recognition of viral membrane gangliosides
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Siglec-1 is a novel dendritic ...... of viral membrane gangliosides
@ast
Siglec-1 is a novel dendritic ...... of viral membrane gangliosides
@en
Siglec-1 is a novel dendritic ...... of viral membrane gangliosides
@nl
type
label
Siglec-1 is a novel dendritic ...... of viral membrane gangliosides
@ast
Siglec-1 is a novel dendritic ...... of viral membrane gangliosides
@en
Siglec-1 is a novel dendritic ...... of viral membrane gangliosides
@nl
prefLabel
Siglec-1 is a novel dendritic ...... of viral membrane gangliosides
@ast
Siglec-1 is a novel dendritic ...... of viral membrane gangliosides
@en
Siglec-1 is a novel dendritic ...... of viral membrane gangliosides
@nl
P2093
P2860
P50
P3181
P1433
P1476
Siglec-1 is a novel dendritic ...... of viral membrane gangliosides
@en
P2093
Bärbel Glass
Elina Erikson
Itziar Erkizia
Maier Lorizate
Maria Pino
Maria T Rodriguez-Plata
Nadine Zangger
Oliver T Keppler
P2860
P304
P3181
P356
10.1371/JOURNAL.PBIO.1001448
P407
P50
P577
2012-01-01T00:00:00Z