Ensemble force changes that result from human cardiac myosin mutations and a small-molecule effector
about
Biophysical properties of human β-cardiac myosin with converter mutations that cause hypertrophic cardiomyopathy.Extraction Protocols for Individual Zebrafish's Ventricle Myosin and Skeletal Muscle Actin for In vitro Motility AssaysSize and speed of the working stroke of cardiac myosin in situ.The myosin activator omecamtiv mecarbil: a promising new inotropic agent.A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice.Actomyosin based contraction: one mechanokinetic model from single molecules to muscle?Heart failure drug changes the mechanoenzymology of the cardiac myosin powerstroke.Contractility parameters of human β-cardiac myosin with the hypertrophic cardiomyopathy mutation R403Q show loss of motor function.Allosteric modulation of cardiac myosin dynamics by omecamtiv mecarbil.A mixed-kinetic model describes unloaded velocities of smooth, skeletal, and cardiac muscle myosin filaments in vitro.Robust mechanobiological behavior emerges in heterogeneous myosin systems.Omecamtiv Mecarbil Enhances the Duty Ratio of Human β-Cardiac Myosin Resulting in Increased Calcium Sensitivity and Slowed Force Development in Cardiac Muscle.Dilated cardiomyopathy myosin mutants have reduced force-generating capacity.Do Actomyosin Single-Molecule Mechanics Data Predict Mechanics of Contracting Muscle?Positive cardiac inotrope omecamtiv mecarbil activates muscle despite suppressing the myosin working strokeControlling load-dependent kinetics of β-cardiac myosin at the single-molecule level
P2860
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P2860
Ensemble force changes that result from human cardiac myosin mutations and a small-molecule effector
description
2015 nî lūn-bûn
@nan
2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Ensemble force changes that re ...... and a small-molecule effector
@ast
Ensemble force changes that re ...... and a small-molecule effector
@en
Ensemble force changes that re ...... and a small-molecule effector
@nl
type
label
Ensemble force changes that re ...... and a small-molecule effector
@ast
Ensemble force changes that re ...... and a small-molecule effector
@en
Ensemble force changes that re ...... and a small-molecule effector
@nl
prefLabel
Ensemble force changes that re ...... and a small-molecule effector
@ast
Ensemble force changes that re ...... and a small-molecule effector
@en
Ensemble force changes that re ...... and a small-molecule effector
@nl
P2093
P2860
P1433
P1476
Ensemble force changes that re ...... and a small-molecule effector
@en
P2093
Elizabeth Choe Yu
James A Spudich
Kathleen M Ruppel
Shirley Sutton
P2860
P304
P356
10.1016/J.CELREP.2015.04.006
P407
P50
P577
2015-04-30T00:00:00Z