Kif14 mutation causes severe brain malformation and hypomyelination
about
Promises, pitfalls and practicalities of prenatal whole exome sequencing.The Genetic Basis of Baculum Size and Shape Variation in Mice.Exome sequencing for gene discovery in lethal fetal disorders--harnessing the value of extreme phenotypes.Genome-Wide Sequencing for Prenatal Detection of Fetal Single-Gene Disorders.The kinesin KIF14 is overexpressed in medulloblastoma and downregulation of KIF14 suppressed tumor proliferation and induced apoptosis.Kif14 overexpression accelerates murine retinoblastoma development.Mutations of KIF14 Cause Primary Microcephaly by Impairing Cytokinesis.Mutations in CIT, encoding citron rho-interacting serine/threonine kinase, cause severe primary microcephaly in humans.Exome sequencing identifies mutations in KIF14 as a novel cause of an autosomal recessive lethal fetal ciliopathy phenotype.Of rings and spines: The multiple facets of Citron proteins in neural development.Biallelic variants in KIF14 cause intellectual disability with microcephaly.A New Way to Treat Brain Tumors: Targeting Proteins Coded by Microcephaly Genes?: Brain tumors and microcephaly arise from opposing derangements regulating progenitor growth. Drivers of microcephaly could be attractive brain tumor targets.Observations on spontaneous tumor formation in mice overexpressing mitotic kinesin Kif14
P2860
Q34558273-A5CECD90-0B57-4646-A240-58F37BE20B95Q36867845-3B7EBF69-E2DB-4AA8-825D-4F87B5870BE3Q38232194-C1398FF9-2E37-4539-94CA-2A60D8ABDE41Q38562550-D835CAD9-A569-417D-976E-09A628F556A4Q38703533-ABA52BE4-1CA4-4EB5-A1B8-AB5837F110EFQ39704584-7FD1CF97-A437-4ECE-BF2B-3FA1CD34A46DQ41918448-9C0EC625-9548-44EF-9E63-FF5EAA3D64F7Q41923165-7D5BC10D-3AFA-42AD-AF7C-571B38C8A591Q41931303-6BBDE848-F1AE-4A5A-9387-B930946B6966Q47352869-093270AD-FF2E-4DE5-9C57-EC35E0EB3033Q47855383-A2FEF3BE-95EA-4C39-B3B1-D343A3E96F51Q52690166-E56A5AE2-4E45-4AAF-9EC1-5940878D6431Q58370838-ECD50B2A-165C-4816-81E8-6297F6738EC1
P2860
Kif14 mutation causes severe brain malformation and hypomyelination
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Kif14 mutation causes severe brain malformation and hypomyelination
@ast
Kif14 mutation causes severe brain malformation and hypomyelination
@en
Kif14 mutation causes severe brain malformation and hypomyelination
@nl
type
label
Kif14 mutation causes severe brain malformation and hypomyelination
@ast
Kif14 mutation causes severe brain malformation and hypomyelination
@en
Kif14 mutation causes severe brain malformation and hypomyelination
@nl
prefLabel
Kif14 mutation causes severe brain malformation and hypomyelination
@ast
Kif14 mutation causes severe brain malformation and hypomyelination
@en
Kif14 mutation causes severe brain malformation and hypomyelination
@nl
P2093
P2860
P1433
P1476
Kif14 mutation causes severe brain malformation and hypomyelination
@en
P2093
Hiroshi Kiyonari
Kenji Tanigaki
Kohei Fujikura
Takaya Abe
Tomiyoshi Setsu
Toshiaki Sakisaka
Toshio Terashima
P2860
P304
P356
10.1371/JOURNAL.PONE.0053490
P407
P577
2013-01-01T00:00:00Z