Combinatorial regulation of meiotic holliday junction resolution in C. elegans by HIM-6 (BLM) helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 nucleases - Wikidata - awgldk - TriplyDB

Combinatorial regulation of meiotic holliday junction resolution in C. elegans by HIM-6 (BLM) helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 nucleases

Combinatorial regulation of meiotic holliday junction resolution in C. elegans by HIM-6 (BLM) helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 nucleases

http://www.wikidata.org/entity/Q27321712

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The SMC-5/6 Complex and the HIM-6 (BLM) Helicase Synergistically Promote Meiotic Recombination Intermediate Processing and Chromosome Maturation during Caenorhabditis elegans Meiosis Joint molecule resolution requires the redundant activities of MUS-81 and XPF-1 during Caenorhabditis elegans meiosis Interplay between structure-specific endonucleases for crossover control during Caenorhabditis elegans meiosis Characterization of the Caenorhabditis elegans HIM-6/BLM helicase: unwinding recombination intermediates The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis Substrate preference of Gen endonucleases highlights the importance of branched structures as DNA damage repair intermediates.Pseudosynapsis and decreased stringency of meiotic repair pathway choice on the hemizygous sex chromosome of Caenorhabditis elegans males Crossover recombination mediated by HIM-18/SLX4-associated nucleases.DNA helicase HIM-6/BLM both promotes MutSγ-dependent crossovers and antagonizes MutSγ-independent interhomolog associations during caenorhabditis elegans meiosis.Drosophila FANCM helicase prevents spontaneous mitotic crossovers generated by the MUS81 and SLX1 nucleases.Msh4 and Msh5 function in SC-independent chiasma formation during the streamlined meiosis of Tetrahymena Trinucleotide expansion in disease: why is there a length threshold?Increased meiotic crossovers and reduced genome stability in absence of Schizosaccharomyces pombe Rad16 (XPF).Rad51/Dmc1 paralogs and mediators oppose DNA helicases to limit hybrid DNA formation and promote crossovers during meiotic recombination An elegans Solution for Crossover Formation.Separable Crossover-Promoting and Crossover-Constraining Aspects of Zip1 Activity during Budding Yeast Meiosis Separable Roles for a Caenorhabditis elegans RMI1 Homolog in Promoting and Antagonizing Meiotic Crossovers Ensure Faithful Chromosome Inheritance.Roles for mismatch repair family proteins in promoting meiotic crossing over.Crossover heterogeneity in the absence of hotspots in Caenorhabditis elegans.E4 ligase-specific ubiquitination hubs coordinate DNA double-strand-break repair and apoptosis A Zip3-like protein plays a role in crossover formation in the SC-less meiosis of the protist Tetrahymena.Holliday junction resolvases.Resolving complex chromosome structures during meiosis: versatile deployment of Smc5/6.Meiotic Recombination: The Essence of Heredity.Bloom syndrome helicase in meiosis: Pro-crossover functions of an anti-crossover protein.Non-SMC Element 2 (NSMCE2) of the SMC5/6 Complex Helps to Resolve Topological Stress.Holliday junction-resolving enzymes-structures and mechanisms.Mutagenic consequences of a single G-quadruplex demonstrate mitotic inheritance of DNA replication fork barriers.Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA.GEN1 from a thermophilic fungus is functionally closely similar to non-eukaryotic junction-resolving enzymes.BRCA2 and RAD51 promote double-strand break formation and cell death in response to gemcitabine.Cooperative control of holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases.LEM-3 is a midbody-tethered DNA nuclease that resolves chromatin bridges during late mitosis.The Caenorhabditis elegans WRN helicase promotes double-strand DNA break repair by mediating end resection and checkpoint activation.Short Inverted Repeats Are Hotspots for Genetic Instability: Relevance to Cancer Genomes.The conserved LEM-3/Ankle1 nuclease is involved in the combinatorial regulation of meiotic recombination repair and chromosome segregation in Caenorhabditis elegans.A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1

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Combinatorial regulation of meiotic holliday junction resolution in C. elegans by HIM-6 (BLM) helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 nucleases

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2013 nî lūn-bûn

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Combinatorial regulation of me ...... -1, MUS-81 and XPF-1 nucleases

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Combinatorial regulation of me ...... -1, MUS-81 and XPF-1 nucleases

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Combinatorial regulation of me ...... -1, MUS-81 and XPF-1 nucleases

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Combinatorial regulation of me ...... -1, MUS-81 and XPF-1 nucleases

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Combinatorial regulation of me ...... -1, MUS-81 and XPF-1 nucleases

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Combinatorial regulation of me ...... -1, MUS-81 and XPF-1 nucleases

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Combinatorial regulation of me ...... -1, MUS-81 and XPF-1 nucleases

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Combinatorial regulation of me ...... -1, MUS-81 and XPF-1 nucleases

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Combinatorial regulation of me ...... -1, MUS-81 and XPF-1 nucleases

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JOURNAL.PGEN.1003591

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Combinatorial regulation of me ...... -1, MUS-81 and XPF-1 nucleases

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Alexander Woglar

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Bettina Meier

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Marlène Jagut

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Remi Sonneville

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P2860

RTEL1 maintains genomic stability by suppressing homologous recombination

Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair

Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair

Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases

The genetics of Caenorhabditis elegans

The Caenorhabditis elegans Aurora B kinase AIR-2 phosphorylates and is required for the localization of a BimC kinesin to meiotic and mitotic spindles

Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy

Meiotic development in Caenorhabditis elegans

ZHP-3 acts at crossovers to couple meiotic recombination with synaptonemal complex disassembly and bivalent formation in C. elegans

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10.1371/JOURNAL.PGEN.1003591

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23901331

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Caenorhabditis elegans

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