PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.
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The Philadelphia chromosome in leukemogenesisCancer cells exploit adaptive mitochondrial dynamics to increase tumor cell invasionRecent development of ATP-competitive small molecule phosphatidylinostitol-3-kinase inhibitors as anticancer agentsMitochondrial Akt Regulation of Hypoxic Tumor ReprogrammingThe Interplay between Oncogenic Signaling Networks and Mitochondrial Dynamics.Autophagy Promotes Focal Adhesion Disassembly and Cell Motility of Metastatic Tumor Cells through the Direct Interaction of Paxillin with LC3AMPK activity regulates trafficking of mitochondria to the leading edge during cell migration and matrix invasion.A neuronal network of mitochondrial dynamics regulates metastasis.The Concerted Action of Mitochondrial Dynamics and Positioning: New Characters in Cancer Onset and Progression.Regulators of mitochondrial dynamics in cancer.The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis.Disabling mitochondrial reprogramming in cancerMolecular Pathways: Mitochondrial Reprogramming in Tumor Progression and Therapy.Fatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer.Overexpression of GAB2 in ovarian cancer cells promotes tumor growth and angiogenesis by upregulating chemokine expression.Overexpression of JARID1B promotes differentiation via SHIP1/AKT signaling in human hypopharyngeal squamous cell carcinoma.Poly(adenosine diphosphate-ribose) polymerase as therapeutic target: lessons learned from its inhibitors.Miro1-mediated mitochondrial positioning shapes intracellular energy gradients required for cell migration.The role of phenotypic plasticity in the escape of cancer cells from targeted therapy.Modeling the Genetic Regulation of Cancer Metabolism: Interplay between Glycolysis and Oxidative Phosphorylation.Adaptive Stress Responses During Tumor Metastasis and Dormancy.Autophagy and epithelial-mesenchymal transition: an intricate interplay in cancer.Mitochondrial dynamics as regulators of cancer biology.The Close Interconnection between Mitochondrial Dynamics and Mitophagy in Cancer.The regulation of tumor cell physiology by mitochondrial dynamics.Mitochondria on the move: emerging paradigms of organelle trafficking in tumour plasticity and metastasis.Pluripotent Stem Cell Metabolism and Mitochondria: Beyond ATP.Different metabolic responses to PI3K inhibition in NSCLC cells harboring wild-type and G12C mutant KRAS.Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer.TGF-β2 initiates autophagy via Smad and non-Smad pathway to promote glioma cells' invasion.Stage-dependent therapeutic efficacy in PI3K/mTOR-driven squamous cell carcinoma of the skin.Mitochondrial Dynamics in Basal and Stressful Conditions.PGC1α promotes cholangiocarcinoma metastasis by upregulating PDHA1 and MPC1 expression to reverse the Warburg effect.CaMKII (Ca2+/Calmodulin-Dependent Kinase II) in Mitochondria of Smooth Muscle Cells Controls Mitochondrial Mobility, Migration, and Neointima Formation.Mitochondrial Delivery of Phenol Substructure Triggers Mitochondrial Depolarization and Apoptosis of Cancer Cells.Arf6-driven cell invasion is intrinsically linked to TRAK1-mediated mitochondrial anterograde trafficking to avoid oxidative catastrophe.Mitochondrial metabolism and cancer
P2860
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P2860
PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.
description
2015 nî lūn-bûn
@nan
2015 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion
@nl
PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.
@ast
PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.
@en
type
label
PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion
@nl
PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.
@ast
PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.
@en
prefLabel
PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion
@nl
PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.
@ast
PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.
@en
P2093
P2860
P50
P3181
P356
P1476
PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.
@en
P2093
Andrew V Kossenkov
Ashani T Weeraratna
Dario C Altieri
Dayana B Rivadeneira
Jagadish C Ghosh
Katherine M Aird
Paolo Rampini
Rugang Zhang
Young Chan Chae
P2860
P304
P3181
P356
10.1073/PNAS.1500722112
P407
P577
2015-06-29T00:00:00Z