Loss of maternal ATRX results in centromere instability and aneuploidy in the mammalian oocyte and pre-implantation embryo
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Endogenous mammalian histone H3.3 exhibits chromatin-related functions during developmentEvery amino acid matters: essential contributions of histone variants to mammalian development and diseaseHistone H3.3 maintains genome integrity during mammalian developmentHistone variant H3.3 maintains a decondensed chromatin state essential for mouse preimplantation developmentHistone variants in metazoan developmentThe presence of the Y-chromosome, not the absence of the second X-chromosome, alters the mRNA levels stored in the fully grown XY mouse oocyte.Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.Viral reprogramming of the Daxx histone H3.3 chaperone during early Epstein-Barr virus infection.ATRX is required for maintenance of the neuroprogenitor cell pool in the embryonic mouse brain.Mouse BRWD1 is critical for spermatid postmeiotic transcription and female meiotic chromosome stability.Regulating the chromatin landscape: structural and mechanistic perspectives.Transplantation of nucleoli into human zygotes: not as simple as expected?ATRX contributes to epigenetic asymmetry and silencing of major satellite transcripts in the maternal genome of the mouse embryoRole of ATRX in chromatin structure and function: implications for chromosome instability and human diseasePostovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes.ATRX induction by mutant huntingtin via Cdx2 modulates heterochromatin condensation and pathology in Huntington's disease.The Daxx/Atrx Complex Protects Tandem Repetitive Elements during DNA Hypomethylation by Promoting H3K9 Trimethylation.Compromised genomic integrity impedes muscle growth after Atrx inactivation.Alpha thalassemia/mental retardation syndrome X-linked gene product ATRX is required for proper replication restart and cellular resistance to replication stress.Epigenetic mechanisms in neurological diseaseAtrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span.Histone H3.3 mutations: a variant path to cancer.Unravelling the proteome of adult rhesus monkey ovaries.Point mutations in an epigenetic factor lead to multiple types of bone tumors: role of H3.3 histone variant in bone development and disease.Chromosomal instability in mammalian pre-implantation embryos: potential causes, detection methods, and clinical consequences.Emerging roles of ATRX in cancer.Identification of protein complexes that bind to histone H3 combinatorial modifications using super-SILAC and weighted correlation network analysis.Daxx regulates mitotic progression and prostate cancer predisposition.XNP/dATRX interacts with DREF in the chromatin to regulate gene expression.The genomic landscape of phaeochromocytoma.CENP-B protects centromere chromatin integrity by facilitating histone deposition via the H3.3-specific chaperone Daxx.Lack of protein kinase C-delta (PKCδ) disrupts fertilization and embryonic development.ATRX in Diffuse Gliomas With its Mosaic/Heterogeneous Expression in a Subset.ATRX in chromatin assembly and genome architecture during development and disease.Mutant ATRX: uncovering a new therapeutic target for glioma.New Epigenetic Drivers of Cancers
P2860
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P2860
Loss of maternal ATRX results in centromere instability and aneuploidy in the mammalian oocyte and pre-implantation embryo
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Loss of maternal ATRX results ...... te and pre-implantation embryo
@ast
Loss of maternal ATRX results ...... te and pre-implantation embryo
@en
Loss of maternal ATRX results ...... te and pre-implantation embryo
@nl
type
label
Loss of maternal ATRX results ...... te and pre-implantation embryo
@ast
Loss of maternal ATRX results ...... te and pre-implantation embryo
@en
Loss of maternal ATRX results ...... te and pre-implantation embryo
@nl
prefLabel
Loss of maternal ATRX results ...... te and pre-implantation embryo
@ast
Loss of maternal ATRX results ...... te and pre-implantation embryo
@en
Loss of maternal ATRX results ...... te and pre-implantation embryo
@nl
P2860
P1433
P1476
Loss of maternal ATRX results ...... te and pre-implantation embryo
@en
P2093
Maria M Viveiros
Rabindranath De La Fuente
P2860
P304
P356
10.1371/JOURNAL.PGEN.1001137
P407
P577
2010-09-23T00:00:00Z