CCL2 accelerates microglia-mediated Abeta oligomer formation and progression of neurocognitive dysfunction
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Impact of Increased Astrocyte Expression of IL-6, CCL2 or CXCL10 in Transgenic Mice on Hippocampal Synaptic FunctionNeuroinflammation in Alzheimer's disease: chemokines produced by astrocytes and chemokine receptorsA deficiency in CCR2+ monocytes: the hidden side of Alzheimer's diseaseDepletion of microglia and inhibition of exosome synthesis halt tau propagation.Presenilin-1 familial Alzheimer's disease mutation alters hippocampal neurogenesis and memory function in CCL2 null mice.Neuroinflammation in Alzheimer's diseaseIntegrated expression profiles of mRNA and miRNA in polarized primary murine microglia.CCL2 affects β-amyloidosis and progressive neurocognitive dysfunction in a mouse model of Alzheimer's disease.Phagocytosis of microglia in the central nervous system diseasesCX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models.Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammationIsoglutaminyl cyclase contributes to CCL2-driven neuroinflammation in Alzheimer's disease.CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer's disease model.The effect of HIV protease inhibitors on amyloid-β peptide degradation and synthesis in human cells and Alzheimer's disease animal modelIntravenous infusion of monocytes isolated from 2-week-old mice enhances clearance of Beta-amyloid plaques in an Alzheimer mouse modelThe classification of microglial activation phenotypes on neurodegeneration and regeneration in Alzheimer's disease brain.FGF2 gene transfer restores hippocampal functions in mouse models of Alzheimer's disease and has therapeutic implications for neurocognitive disordersCCL2 is associated with a faster rate of cognitive decline during early stages of Alzheimer's diseaseAltered hippocampal synaptic transmission in transgenic mice with astrocyte-targeted enhanced CCL2 expression.A Comprehensive Behavioral Test Battery to Assess Learning and Memory in 129S6/Tg2576 MiceChemokines Referee Inflammation within the Central Nervous System during Infection and DiseaseThe anti-inflammatory glycoprotein, CD200, restores neurogenesis and enhances amyloid phagocytosis in a mouse model of Alzheimer's disease.Synaptic plasticity in the hippocampus shows resistance to acute ethanol exposure in transgenic mice with astrocyte-targeted enhanced CCL2 expression.Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer's diseaseGlia maturation factor induces interleukin-33 release from astrocytes: implications for neurodegenerative diseases.CCR5 deficiency accelerates lipopolysaccharide-induced astrogliosis, amyloid-beta deposit and impaired memory function.Diverse activation of microglia by chemokine (C-C motif) ligand 2 overexpression in brain.The mixed-lineage kinase 3 inhibitor URMC-099 facilitates microglial amyloid-β degradationMCP-1 and eotaxin-1 selectively and negatively associate with memory in MCI and Alzheimer's disease dementia phenotypes.Microglia convert aggregated amyloid-β into neurotoxic forms through the shedding of microvesicles.Microglia and inflammation in Alzheimer's disease.Macrophages in Alzheimer's disease: the blood-borne identity.Microglia and neurodegeneration: the role of systemic inflammation.Clearance of amyloid-β peptides by microglia and macrophages: the issue of what, when and where.Role of chemokine CCL2 and its receptor CCR2 in neurodegenerative diseases.The interplay between iron accumulation, mitochondrial dysfunction, and inflammation during the execution step of neurodegenerative disorders.Migration of blood cells to β-amyloid plaques in Alzheimer's disease.High-protein diet promotes sensitivity to cholecystokinin and shifts the cecal microbiome without altering brain inflammation in diet-induced obesity in rats.Methyl donor supplementation alters cognitive performance and motivation in female offspring from high-fat diet-fed dams.Impact of Cytokines and Chemokines on Alzheimer's Disease Neuropathological Hallmarks.
P2860
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P2860
CCL2 accelerates microglia-mediated Abeta oligomer formation and progression of neurocognitive dysfunction
description
2009 nî lūn-bûn
@nan
2009 թուականին հրատարակուած գիտական յօդուած
@hyw
2009 թվականին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
CCL2 accelerates microglia-med ...... of neurocognitive dysfunction
@ast
CCL2 accelerates microglia-med ...... of neurocognitive dysfunction
@en
CCL2 accelerates microglia-med ...... of neurocognitive dysfunction
@nl
type
label
CCL2 accelerates microglia-med ...... of neurocognitive dysfunction
@ast
CCL2 accelerates microglia-med ...... of neurocognitive dysfunction
@en
CCL2 accelerates microglia-med ...... of neurocognitive dysfunction
@nl
prefLabel
CCL2 accelerates microglia-med ...... of neurocognitive dysfunction
@ast
CCL2 accelerates microglia-med ...... of neurocognitive dysfunction
@en
CCL2 accelerates microglia-med ...... of neurocognitive dysfunction
@nl
P2093
P2860
P3181
P1433
P1476
CCL2 accelerates microglia-med ...... of neurocognitive dysfunction
@en
P2093
Howard E Gendelman
Huangui Xiong
Mary P Lambert
Masaru Yamamoto
Richard M Ransohoff
Tomomi Kiyota
William L Klein
P2860
P3181
P356
10.1371/JOURNAL.PONE.0006197
P407
P577
2009-01-01T00:00:00Z