Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice
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Environmental toxicants, epigenetics, and cancerThe roles of co-chaperone CCRP/DNAJC7 in Cyp2b10 gene activation and steatosis development in mouse liversNon-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylomeDioxin induces Ahr-dependent robust DNA demethylation of the Cyp1a1 promoter via Tdg in the mouse liverThe innovative medicines initiative: a European response to the innovation challenge.Gene and genome parameters of mammalian liver circadian genes (LCGs).Association of childhood chronic physical aggression with a DNA methylation signature in adult human T cells.RNA-Seq reveals common and unique PXR- and CAR-target gene signatures in the mouse liver transcriptome.Neonatal activation of the nuclear receptor CAR results in epigenetic memory and permanent change of drug metabolism in mouse liverEmphasising the European Union's Commitment to Cancer Research: a helicopter view of the Seventh Framework Programme for Research and Technological Development.The signature of maternal rearing in the methylome in rhesus macaque prefrontal cortex and T cellsEvidence that the capacity of nongenotoxic carcinogens to induce oxidative stress is subject to marked variability.Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver.Mechanisms of induction of cytosolic and microsomal glutathione transferase (GST) genes by xenobiotics and pro-inflammatory agents.Investigative safety science as a competitive advantage for Pharma.Impact of physiological, pathological and environmental factors on the expression and activity of human cytochrome P450 2D6 and implications in precision medicine.Feed-drug interaction of orally applied butyrate and phenobarbital on hepatic cytochrome P450 activity in chickens.Methylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus-Associated Hepatocellular Carcinoma.Loss of Tet1-Associated 5-Hydroxymethylcytosine Is Concomitant with Aberrant Promoter Hypermethylation in Liver Cancer.Balance of DNA methylation and demethylation in cancer development.Genome-wide screening identifies Plasmodium chabaudi-induced modifications of DNA methylation status of Tlr1 and Tlr6 gene promoters in liver, but not spleen, of female C57BL/6 mice.A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogens.Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.Ha-ras and β-catenin oncoproteins orchestrate metabolic programs in mouse liver tumors.Defining baseline epigenetic landscapes in the rat liver.Effects of Phenobarbital on Expression of UDP-Glucuronosyltransferase 1a6 and 1a7 in Rat Brain.Investigation into the role of the germline epigenome in the transmission of glucocorticoid-programmed effects across generations.Epigenomics - Impact for Drug Safety Sciences
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P2860
Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
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2011 թվականին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
Phenobarbital mediates an epig ...... 10 in the liver of B6C3F1 mice
@ast
Phenobarbital mediates an epig ...... 10 in the liver of B6C3F1 mice
@en
Phenobarbital mediates an epig ...... 10 in the liver of B6C3F1 mice
@nl
type
label
Phenobarbital mediates an epig ...... 10 in the liver of B6C3F1 mice
@ast
Phenobarbital mediates an epig ...... 10 in the liver of B6C3F1 mice
@en
Phenobarbital mediates an epig ...... 10 in the liver of B6C3F1 mice
@nl
prefLabel
Phenobarbital mediates an epig ...... 10 in the liver of B6C3F1 mice
@ast
Phenobarbital mediates an epig ...... 10 in the liver of B6C3F1 mice
@en
Phenobarbital mediates an epig ...... 10 in the liver of B6C3F1 mice
@nl
P2093
P2860
P3181
P1433
P1476
Phenobarbital mediates an epig ...... 10 in the liver of B6C3F1 mice
@en
P2093
Arne Müller
Axel Vicart
Dirk Schübeler
Enrico Funhoff
Jennifer Marlowe
Jonathan Moggs
Laurent Morawiec
Natasa Zamurovic
Olivier Grenet
Philippe Couttet
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0018216
P407
P577
2011-01-01T00:00:00Z