Mutations abrogating the RNase activity in glycoprotein E(rns) of the pestivirus classical swine fever virus lead to virus attenuation
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Immune Responses Against Classical Swine Fever Virus: Between Ignorance and LunacyStructures and Functions of Pestivirus Glycoproteins: Not Simply Surface MattersThe E2 glycoprotein of classical swine fever virus is a virulence determinant in swine.Passage of classical swine fever virus in cultured swine kidney cells selects virus variants that bind to heparan sulfate due to a single amino acid change in envelope protein E(rns)Interaction of classical swine fever virus with membrane-associated heparan sulfate: role for virus replication in vivo and virulence.The carboxy-terminal sequence of the pestivirus glycoprotein E(rns) represents an unusual type of membrane anchor.A structural model of pestivirus E(rns) based on disulfide bond connectivity and homology modeling reveals an extremely rare vicinal disulfideRecovery of Virulent and RNase-Negative Attenuated Type 2 Bovine Viral Diarrhea Viruses from Infectious cDNA ClonesN-Linked Glycosylation Status of Classical Swine Fever Virus Strain Brescia E2 Glycoprotein Influences Virulence in SwineBovine Viral Diarrhea Virus: Prevention of Persistent Fetal Infection by a Combination of Two Mutations Affecting Erns RNase and Npro ProteaseCytopathogenicity of Classical Swine Fever Virus Correlates with Attenuation in the Natural HostMutation of Cysteine 171 of Pestivirus Erns RNase Prevents Homodimer Formation and Leads to Attenuation of Classical Swine Fever VirusA New Type of Signal Peptidase Cleavage Site Identified in an RNA Virus PolyproteinStructure-function analysis of Rny1 in tRNA cleavage and growth inhibitionClassical Swine Fever-An Updated ReviewAntibody responses of pigs to defined Erns fragments after infection with classical swine fever virus.The nsp2 replicase proteins of murine hepatitis virus and severe acute respiratory syndrome coronavirus are dispensable for viral replication.T2 Family ribonucleases: ancient enzymes with diverse roles.The core protein of classical Swine Fever virus is dispensable for virus propagation in vitroEfficient sensing of infected cells in absence of virus particles by plasmacytoid dendritic cells is blocked by the viral ribonuclease E(rns.).Structure of the membrane anchor of pestivirus glycoprotein E(rns), a long tilted amphipathic helix.Lipid Binding of the Amphipathic Helix Serving as Membrane Anchor of Pestivirus Glycoprotein ErnsSelection of classical swine fever virus with enhanced pathogenicity reveals synergistic virulence determinants in E2 and NS4BPathology and molecular diagnosis of classical swine fever in Mizoram.Substitution of specific cysteine residues in the E1 glycoprotein of classical swine fever virus strain Brescia affects formation of E1-E2 heterodimers and alters virulence in swine.Role for bovine viral diarrhea virus Erns glycoprotein in the control of activation of beta interferon by double-stranded RNACharacterization of helper virus-independent cytopathogenic classical swine fever virus generated by an in vivo RNA recombination system.Determinants of virulence of classical swine fever virus strain Brescia.Classical swine fever virus glycoprotein E rns is an endoribonuclease with an unusual base specificity.
P2860
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P2860
Mutations abrogating the RNase activity in glycoprotein E(rns) of the pestivirus classical swine fever virus lead to virus attenuation
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Mutations abrogating the RNase ...... irus lead to virus attenuation
@ast
Mutations abrogating the RNase ...... irus lead to virus attenuation
@en
Mutations abrogating the RNase ...... irus lead to virus attenuation
@nl
type
label
Mutations abrogating the RNase ...... irus lead to virus attenuation
@ast
Mutations abrogating the RNase ...... irus lead to virus attenuation
@en
Mutations abrogating the RNase ...... irus lead to virus attenuation
@nl
prefLabel
Mutations abrogating the RNase ...... irus lead to virus attenuation
@ast
Mutations abrogating the RNase ...... irus lead to virus attenuation
@en
Mutations abrogating the RNase ...... irus lead to virus attenuation
@nl
P2860
P1433
P1476
Mutations abrogating the RNase ...... irus lead to virus attenuation
@en
P2093
P2860
P304
10224-10235
P577
1999-12-01T00:00:00Z