Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase - Wikidata - awgldk - TriplyDB

Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase

Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase

http://www.wikidata.org/entity/Q27469958

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Structural and functional characterizations reveal the importance of a zinc binding domain in Bloom's syndrome helicase Hepatitis C virus subgenomic replicon requires an active NS3 RNA helicase.Structurally conserved amino Acid w501 is required for RNA helicase activity but is not essential for DNA helicase activity of hepatitis C virus NS3 protein.Hepatitis C Virus NS3 ATPases/Helicases from Different Genotypes Exhibit Variations in Enzymatic Properties Inhibition of Hepatitis C Virus Nonstructural Protein, Helicase Activity, and Viral Replication by a Recombinant Human Antibody Clone Cleavage preference distinguishes the two-component NS2B–NS3 serine proteinases of Dengue and West Nile viruses Role of Divalent Metal Cations in ATP Hydrolysis Catalyzed by the Hepatitis C Virus NS3 Helicase: Magnesium Provides a Bridge for ATP to Fuel Unwinding Coordinate Replication of Alfalfa Mosaic Virus RNAs 1 and 2 Involves cis- and trans-Acting Functions of the Encoded Helicase-Like and Polymerase-Like Domains NS3 Helicase Domains Involved in Infectious Intracellular Hepatitis C Virus Particle Assembly Bluetongue virus: dissection of the polymerase complex Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism.Visualizing ATP-Dependent RNA Translocation by the NS3 Helicase from HCV Hepatitis C virus RNA replication depends on specific cis- and trans-acting activities of viral nonstructural proteins Double-stranded DNA-induced localized unfolding of HCV NS3 helicase subdomain 2.ATP requirement for Prp5p function is determined by Cus2p and the structure of U2 small nuclear RNA.Induction of cell-mediated immune responses in mice by DNA vaccines that express hepatitis C virus NS3 mutants lacking serine protease and NTPase/RNA helicase activities.Intracytoplasmic stable expression of IgG1 antibody targeting NS3 helicase inhibits replication of highly efficient hepatitis C Virus 2a clone.Brome mosaic virus 1a nucleoside triphosphatase/helicase domain plays crucial roles in recruiting RNA replication templates.The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target Agrobacterium rhizogenes GALLS protein contains domains for ATP binding, nuclear localization, and type IV secretion.Analysis of the Enzymatic Activity of an NS3 Helicase Genotype 3a Variant Sequence Obtained from a Relapse Patient.Understanding helicases as a means of virus control.Snf2 family ATPases and DExx box helicases: differences and unifying concepts from high-resolution crystal structures Two novel conserved motifs in the hepatitis C virus NS3 protein critical for helicase action.Molecular mechanism of divalent-metal-induced activation of NS3 helicase and insights into Zika virus inhibitor design.Electrostatic analysis of the hepatitis C virus NS3 helicase reveals both active and allosteric site locations.Comparison of structural architecture of HCV NS3 genotype 1 versus Pakistani genotype 3a.Defining the structure-function relationships of bluetongue virus helicase protein VP6.Limited suppression of the interferon-beta production by hepatitis C virus serine protease in cultured human hepatocytes.Mechanism of flexibility control for ATP access of hepatitis C virus NS3 helicase.The serine protease domain of hepatitis C viral NS3 activates RNA helicase activity by promoting the binding of RNA substrate.ATPase/helicase motif mutants of Escherichia coli PriA protein essential for recombination-dependent DNA replication.RecA-like domain 2 of DNA-dependent ATPase A domain, a SWI2/SNF2 protein, mediates conformational integrity and ATP hydrolysis.

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Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase

http://www.wikidata.org/entity/Q27469958

description

2001 nî lūn-bûn

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2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase

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Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase

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Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase

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Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase

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Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase

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Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase

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Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase

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Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase

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Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase

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JVI.75.17.8289-8297.2001

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Journal of Virology

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Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase

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C L Tai

http://www.w3.org/2001/XMLSchema#string

L H Hwang

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S H Liaw

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U C Yang

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P2860

Evolution and taxonomy of positive-strand RNA viruses: implications of comparative analysis of amino acid sequences

Mutational analysis of a DEAD box RNA helicase: the mammalian translation initiation factor eIF-4A

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold

Two related superfamilies of putative helicases involved in replication, recombination, repair and expression of DNA and RNA genomes

Multiple enzymatic activities associated with recombinant NS3 protein of hepatitis C virus

Structure-based mutagenesis study of hepatitis C virus NS3 helicase

The helicase activity associated with hepatitis C virus nonstructural protein 3 (NS3)

Virus-encoded RNA helicases

Comparisons between the structures of HCV and Rep helicases reveal structural similarities between SF1 and SF2 super-families of helicases

Mutational analysis of the hepatitis C virus RNA helicase

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