Down-regulation of the retinoblastoma tumor suppressor by the hepatitis C virus NS5B RNA-dependent RNA polymerase - Wikidata - awgldk - TriplyDB

Down-regulation of the retinoblastoma tumor suppressor by the hepatitis C virus NS5B RNA-dependent RNA polymerase

Down-regulation of the retinoblastoma tumor suppressor by the hepatitis C virus NS5B RNA-dependent RNA polymerase

http://www.wikidata.org/entity/Q27472746

about

Hepatitis C virus proteins Viruses associated with human cancer Significance of hepatitis virus infection in the oncogenic initiation of hepatocellular carcinoma Immune and non-immune responses to hepatitis C virus infection Autophagy in hepatitis C virus-host interactions: potential roles and therapeutic targets for liver-associated diseases Lymphotoxin signaling is initiated by the viral polymerase in HCV-linked tumorigenesis Hepatitis C Virus Induces E6AP-Dependent Degradation of the Retinoblastoma Protein A Locking Mechanism Regulates RNA Synthesis and Host Protein Interaction by the Hepatitis C Virus Polymerase 1,5-Benzodiazepines, a Novel Class of Hepatitis C Virus Polymerase Nonnucleoside Inhibitors Impaired Replication of Hepatitis C Virus Containing Mutations in a Conserved NS5B Retinoblastoma Protein-Binding Motif A cell-based assay for RNA synthesis by the HCV polymerase reveals new insights on mechanism of polymerase inhibitors and modulation by NS5A TGFbeta induces apoptosis and EMT in primary mouse hepatocytes independently of p53, p21Cip1 or Rb status.Unique impact of RB loss on hepatic proliferation: tumorigenic stresses uncover distinct pathways of cell cycle control.Virus associated malignancies: the role of viral hepatitis in hepatocellular carcinoma.Regulation of de novo-initiated RNA synthesis in hepatitis C virus RNA-dependent RNA polymerase by intermolecular interactions.Hepatocarcinogenesis associated with hepatitis B, delta and C viruses.Hepatitis C virus NS5B protein delays s phase progression in human hepatocyte-derived cells by relocalizing cyclin-dependent kinase 2-interacting protein (CINP).Viral double-strand RNA-binding proteins can enhance innate immune signaling by toll-like Receptor 3.Phosphorylation of hepatitis C virus RNA polymerases ser29 and ser42 by protein kinase C-related kinase 2 regulates viral RNA replication.RB has a critical role in mediating the in vivo checkpoint response, mitigating secondary DNA damage and suppressing liver tumorigenesis initiated by aflatoxin B1 Mechanisms of HCV-induced liver cancer: what did we learn from in vitro and animal studies?A subclone of HuH-7 with enhanced intracellular hepatitis C virus production and evasion of virus related-cell cycle arrest.Oncogenic potential of hepatitis C virus proteins Is hepatitis C virus carcinogenic?Tumor suppressors, chromosomal instability, and hepatitis C virus-associated liver cancer.Pathogenesis and prevention of hepatitis C virus-induced hepatocellular carcinoma.Hepatitis C virus infection: establishment of chronicity and liver disease progression Quantification of Hepatitis C Virus Cell-to-Cell Spread Using a Stochastic Modeling Approach.Hepatitis C virus-induced hepatocellular carcinoma Changing the ubiquitin landscape during viral manipulation of the DNA damage response.How do persistent infections with hepatitis C virus cause liver cancer?Hepatitis C virus and cellular stress response: implications to molecular pathogenesis of liver diseases.Hepatitis C virus-related hepatocellular carcinoma: An insight into molecular mechanisms and therapeutic strategies Virus-specific mechanisms of carcinogenesis in hepatitis C virus associated liver cancer How Hepatitis C Virus Leads to Hepatocellular Carcinoma: A Network-Based Study.ANALYSIS OF HEPATITIS C VIRUS INFECTION MODELS WITH HEPATOCYTE HOMEOSTASIS White spot syndrome virus IE1 and WSV056 modulate the G1/S transition by binding to the host retinoblastoma protein.Destabilization of Rb by human papillomavirus E7 is cell cycle dependent: E2-25K is involved in the proteolysis.Cellular and molecular biology of HCV infection and hepatitis.Roles of the two distinct proteasome pathways in hepatitis C virus infection.

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P2860

Down-regulation of the retinoblastoma tumor suppressor by the hepatitis C virus NS5B RNA-dependent RNA polymerase

http://www.wikidata.org/entity/Q27472746

description

2005 nî lūn-bûn

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2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Down-regulation of the retinob ...... B RNA-dependent RNA polymerase

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Down-regulation of the retinob ...... B RNA-dependent RNA polymerase

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Down-regulation of the retinob ...... B RNA-dependent RNA polymerase

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type

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Down-regulation of the retinob ...... B RNA-dependent RNA polymerase

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Down-regulation of the retinob ...... B RNA-dependent RNA polymerase

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Down-regulation of the retinob ...... B RNA-dependent RNA polymerase

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Down-regulation of the retinob ...... B RNA-dependent RNA polymerase

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Down-regulation of the retinob ...... B RNA-dependent RNA polymerase

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Down-regulation of the retinob ...... B RNA-dependent RNA polymerase

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Proceedings of the National Academy of Sciences of the United States of America

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Down-regulation of the retinob ...... B RNA-dependent RNA polymerase

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P2093

Kui Li

http://www.w3.org/2001/XMLSchema#string

Mitsuyasu Nakamura

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Stanley M Lemon

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Tsubasa Munakata

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Yuqiong Liang

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P2860

Involvement of p21(WAF1/Cip1), p27(Kip1), and p18(INK4c) in troglitazone-induced cell-cycle arrest in human hepatoma cell lines

Differential roles of two tandem E2F sites in repression of the human p107 promoter by retinoblastoma and p107 proteins

BRCA1-associated growth arrest is RB-dependent

Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3' nontranslated region are essential for virus replication in vivo

Selectable subgenomic and genome-length dicistronic RNAs derived from an infectious molecular clone of the HCV-N strain of hepatitis C virus replicate efficiently in cultured Huh7 cells.

The hepatitis C virus RNA-dependent RNA polymerase membrane insertion sequence is a transmembrane segment.

Identification of the Hepatitis C Virus RNA Replication Complex in Huh-7 Cells Harboring Subgenomic Replicons

Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site

Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7

Hepatitis C virus infection is associated with the development of hepatocellular carcinoma

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16332962

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