High-throughput assays using a luciferase-expressing replicon, virus-like particles, and full-length virus for West Nile virus drug discovery.
about
In vitro resistance selection and in vivo efficacy of morpholino oligomers against West Nile virusTriaryl pyrazoline compound inhibits flavivirus RNA replication.Structure and Function of Flavivirus NS5 MethyltransferaseEssential Role of Dengue Virus Envelope Protein N Glycosylation at Asparagine-67 during Viral PropagationA mouse cell-adapted NS4B mutation attenuates West Nile virus RNA synthesisIdentification of Novel Small-Molecule Inhibitors of West Nile Virus InfectionSelection and Analysis of Mutations in an Encephalomyocarditis Virus Internal Ribosome Entry Site That Improve the Efficiency of a Bicistronic Flavivirus ConstructWest Nile Virus Methyltransferase Catalyzes Two Methylations of the Viral RNA Cap through a Substrate-Repositioning MechanismGenetic Interactions among the West Nile Virus Methyltransferase, the RNA-Dependent RNA Polymerase, and the 5' Stem-Loop of Genomic RNAIdentification and Biochemical Characterization of Small-Molecule Inhibitors of West Nile Virus Serine Protease by a High-Throughput ScreenAntiviral effect of interferon lambda against West Nile virusCyclosporine Inhibits Flavivirus Replication through Blocking the Interaction between Host Cyclophilins and Viral NS5 ProteinAssay development and high-throughput antiviral drug screening against Bluetongue virusIdentification of Inhibitors of Yellow Fever Virus Replication Using a Replicon-Based High-Throughput AssayExclusion of West Nile Virus Superinfection through RNA ReplicationThe development, optimization and validation of an assay for high throughput antiviral drug screening against Dengue virusA Rapid Zika Diagnostic Assay to Measure Neutralizing Antibodies in PatientsPlasmodium falciparum: development of a transgenic line for screening antimalarials using firefly luciferase as the reporter.Identification and characterization of inhibitors of West Nile virus.The use of RNAi-based screens to identify host proteins involved in viral replicationHTS-driven discovery of new chemotypes with West Nile Virus inhibitory activity.A single-amino acid substitution in West Nile virus 2K peptide between NS4A and NS4B confers resistance to lycorine, a flavivirus inhibitor.Generation of West Nile virus infectious clones containing amino acid insertions between capsid and capsid anchor.Virtual ligand screening of the National Cancer Institute (NCI) compound library leads to the allosteric inhibitory scaffolds of the West Nile Virus NS3 proteinase.West Nile virus infectious replicon particles generated using a packaging-restricted cell line is a safe reporter system.Identification of luteolin as enterovirus 71 and coxsackievirus A16 inhibitors through reporter viruses and cell viability-based screeningInhibition of dengue virus by an ester prodrug of an adenosine analog.Identification of five interferon-induced cellular proteins that inhibit west nile virus and dengue virus infections.High-throughput screening for broad-spectrum chemical inhibitors of RNA viruses.Highly conserved residues in the helical domain of dengue virus type 1 precursor membrane protein are involved in assembly, precursor membrane (prM) protein cleavage, and entry.The C-terminal helical domain of dengue virus precursor membrane protein is involved in virus assembly and entry.Assays for the identification of novel antivirals against bluetongue virus.Keratinocytes are cell targets of West Nile virus in vivo.The helical domains of the stem region of dengue virus envelope protein are involved in both virus assembly and entryThe combined use of alphavirus replicons and pseudoinfectious particles for the discovery of antivirals derived from natural products.Mosquito cell-derived West Nile virus replicon particles mimic arbovirus inoculum and have reduced spread in mice.Rab8b Regulates Transport of West Nile Virus Particles from Recycling EndosomesFlavivirus methyltransferase: a novel antiviral targetConstruction and characterisation of a complete reverse genetics system of dengue virus type 3.West Nile virus infection and immunity.
P2860
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P2860
High-throughput assays using a luciferase-expressing replicon, virus-like particles, and full-length virus for West Nile virus drug discovery.
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
High-Throughput Assays Using a ...... West Nile Virus Drug Discovery
@nl
High-throughput assays using a ...... est Nile virus drug discovery.
@ast
High-throughput assays using a ...... est Nile virus drug discovery.
@en
type
label
High-Throughput Assays Using a ...... West Nile Virus Drug Discovery
@nl
High-throughput assays using a ...... est Nile virus drug discovery.
@ast
High-throughput assays using a ...... est Nile virus drug discovery.
@en
prefLabel
High-Throughput Assays Using a ...... West Nile Virus Drug Discovery
@nl
High-throughput assays using a ...... est Nile virus drug discovery.
@ast
High-throughput assays using a ...... est Nile virus drug discovery.
@en
P2093
P2860
P1476
High-throughput assays using a ...... est Nile virus drug discovery.
@en
P2093
David M Ferguson
Francesc Puig-Basagoiti
Mark Tilgner
Tia S Deas
P2860
P304
P356
10.1128/AAC.49.12.4980-4988.2005
P407
P50
P577
2005-12-01T00:00:00Z