Structure-Based Mutational Analysis of the NS3 Helicase from Dengue Virus - Wikidata - awgldk - TriplyDB

Structure-Based Mutational Analysis of the NS3 Helicase from Dengue Virus

Structure-Based Mutational Analysis of the NS3 Helicase from Dengue Virus

http://www.wikidata.org/entity/Q27473280

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Molecular targets for flavivirus drug discovery Structure and functionality in flavivirus NS-proteins: perspectives for drug design Synergistic interactions between the NS3(hel) and E proteins contribute to the virulence of dengue virus type 1 Crystal Structure of the Dengue Virus RNA-Dependent RNA Polymerase Catalytic Domain at 1.85-Angstrom Resolution Crystal Structure of the NS3 Protease-Helicase from Dengue Virus The Two-component NS2B-NS3 Proteinase Represses DNA Unwinding Activity of the West Nile Virus NS3 Helicase Focus on flaviviruses: current and future drug targets Flexibility between the protease and helicase domains of the dengue virus NS3 protein conferred by the linker region and its functional implications Steady-state NTPase activity of Dengue virus NS3: number of catalytic sites, nucleotide specificity and activation by ssRNA.Induction of a protective response in mice by the dengue virus NS3 protein using DNA vaccines.Comparative analysis of full-length genomic sequences of 10 dengue serotype 1 viruses associated with different genotypes, epidemics, and disease severity isolated in Thailand over 22 years The C-terminal 50 amino acid residues of dengue NS3 protein are important for NS3-NS5 interaction and viral replication Design, synthesis and characterization of novel 1,2-benzisothiazol-3(2H)-one and 1,3,4-oxadiazole hybrid derivatives: potent inhibitors of Dengue and West Nile virus NS2B/NS3 proteases Molecular mechanism of divalent-metal-induced activation of NS3 helicase and insights into Zika virus inhibitor design.NS3 protease from flavivirus as a target for designing antiviral inhibitors against dengue virus Organization of the Flavivirus RNA replicase complex.Exploring dengue genome to construct a multi-epitope based subunit vaccine by utilizing immunoinformatics approach to battle against dengue infection.Structural and functional parameters of the flaviviral protease: a promising antiviral drug target.Analysis of the nucleoside triphosphatase, RNA triphosphatase, and unwinding activities of the helicase domain of dengue virus NS3 protein.The role of surface basic amino acids of dengue virus NS3 helicase in viral RNA replication and enzyme activities.NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication.Allostery in the dengue virus NS3 helicase: Insights into the NTPase cycle from molecular simulations.Targeting intramolecular proteinase NS2B/3 cleavages for -dominant inhibition of dengue virus

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P2860

Structure-Based Mutational Analysis of the NS3 Helicase from Dengue Virus

http://www.wikidata.org/entity/Q27473280

description

2006 nî lūn-bûn

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2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի հուլիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Structure-Based Mutational Analysis of the NS3 Helicase from Dengue Virus

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Structure-Based Mutational Analysis of the NS3 Helicase from Dengue Virus

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Structure-Based Mutational Analysis of the NS3 Helicase from Dengue Virus

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type

label

Structure-Based Mutational Analysis of the NS3 Helicase from Dengue Virus

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Structure-Based Mutational Analysis of the NS3 Helicase from Dengue Virus

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Structure-Based Mutational Analysis of the NS3 Helicase from Dengue Virus

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prefLabel

Structure-Based Mutational Analysis of the NS3 Helicase from Dengue Virus

@ast

Structure-Based Mutational Analysis of the NS3 Helicase from Dengue Virus

@en

Structure-Based Mutational Analysis of the NS3 Helicase from Dengue Virus

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Journal of Virology

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Structure-Based Mutational Analysis of the NS3 Helicase from Dengue Virus

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P2093

Alex Chao

http://www.w3.org/2001/XMLSchema#string

Aruna Sampath

http://www.w3.org/2001/XMLSchema#string

Subhash G Vasudevan

http://www.w3.org/2001/XMLSchema#string

Ting Xu

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P2860

Two related superfamilies of putative helicases involved in replication, recombination, repair and expression of DNA and RNA genomes

The serine protease and RNA-stimulated nucleoside triphosphatase and RNA helicase functional domains of dengue virus type 2 NS3 converge within a region of 20 amino acids

Structure-based mutagenesis study of hepatitis C virus NS3 helicase

Assignment of the multifunctional NS3 protein of bovine viral diarrhea virus during RNA replication: an in vivo and in vitro study

Purification and Characterization of West Nile Virus Nucleoside Triphosphatase (NTPase)/Helicase: Evidence for Dissociation of the NTPase and Helicase Activities of the Enzyme

Mutagenesis of the Dengue virus type 2 NS3 protein within and outside helicase motifs: effects on enzyme activity and virus replication.

Structure of the Flavivirus helicase: implications for catalytic activity, protein interactions, and proteolytic processing.

Structure of the Dengue Virus Helicase/Nucleoside Triphosphatase Catalytic Domain at a Resolution of 2.4 A

RNA translocation and unwinding mechanism of HCV NS3 helicase and its coordination by ATP

Mutational analysis of the hepatitis C virus RNA helicase

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6686-90

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10.1128/JVI.02215-05

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13

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80

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16775356

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virus structure

P932

1488930

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